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The Microbial Protein Interaction Database

Interaction Evidences

phoQ - phoP ( Escherichia coli (strain K12) )

Protein A	Protein B
P23837 Sensor protein phoQ phoQ b1129, JW1115	P23836 Transcriptional regulatory protein phoP phoP b1130, JW1116
CMR Search...	CMR Search...
GO MF: two-component sensor activity GO MF: magnesium ion binding GO MF: ATP binding GO CC: integral to membrane GO CC: plasma membrane GO BP: peptidyl-histidine phosphorylation GO BP: two-component signal transduction system (p...	GO MF: DNA binding GO MF: two-component response regulator activity GO CC: cytoplasm GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (97)

Experiments (2)

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

Interologs (94)

phoQ (80%) - phoP (90%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 85% Positives: 91% E-Value: 0

Method	DB Source	Type	Publication
far western blotting		physical association	Chamnongpol S et al. (2000)
surface plasmon resonance		physical association	Castelli ME et al. (2003)

MXAN_5314 (16%) - MXAN_3450 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 36% E-Value: 1.50e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

creC (15%) - creB (34%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 1.50e-19

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

kdpD (14%) - kdpE (35%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 7.20e-22

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Luttmann D et al. (2009)
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)
enzymatic study		physical association	Heermann R et al. (2003)
protein kinase assay		physical association	Luttmann D et al. (2009)

MXAN_4165 (15%) - MXAN_4164 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 38% E-Value: 3.58e-17

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sll0798 (12%) - sll0797 (36%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 1.27e-18

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

kdpD (12%) - A2VGV6 (36%) (Mycobacterium tuberculosis C - Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 21% Positives: 36% E-Value: 2.56e-23

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Davey CA et al. (2002)

prrB (14%) - prrA (32%) (Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 21% Positives: 38% E-Value: 3.13e-21

Method	DB Source	Type	Publication
enzymatic study		direct interaction	Nowak E et al. (2006)

rstB (14%) - rstA (30%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 21% Positives: 35% E-Value: 3.83e-15

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

MXAN_5211 (13%) - MXAN_3450 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 1.04e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_3450 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 35% E-Value: 2.03e-20

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_4164 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 36% E-Value: 2.93e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cpxA (14%) - cpxR (29%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 20% Positives: 36% E-Value: 3.70e-18

Method	DB Source	Type	Publication
unspecified method		physical association	Nakayama S et al. (2003)

sll0790 (13%) - sll0789 (31%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 7.45e-19

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

slr0533 (13%) - sll0649 (32%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 20% Positives: 34% E-Value: 2.32e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

basS (12%) - basR (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 1.04e-20

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

MXAN_2606 (13%) - MXAN_5995 (29%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 34% E-Value: 4.83e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5314 (16%) - MXAN_7396 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 32% E-Value: 4.38e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (13%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 34% E-Value: 5.16e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 1.01e-19

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5211 (13%) - MXAN_1680 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 33% E-Value: 1.01e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_3450 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 34% E-Value: 8.80e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (13%) - MXAN_4164 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 1.50e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

basS (12%) - basR (31%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 19% Positives: 34% E-Value: 1.15e-19

Method	DB Source	Type	Publication
coimmunoprecipitation		physical association	Kato A et al. (2004)

yycG (12%) - yycF (32%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 19% Positives: 34% E-Value: 1.11e-18

Method	DB Source	Type	Publication
enzymatic study		physical association	Fukuchi K et al. (2000)

envZ (11%) - ompR (35%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 19% Positives: 35% E-Value: 6.74e-20

Method	DB Source	Type	Publication
electrophoretic mobility shift assay		physical association	Harlocker SL et al. (1995)
far western blotting		physical association	Cai SJ et al. (2002)
pull down		physical association	Cai SJ et al. (2002)

phoR1 (12%) - phoP3 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 34% E-Value: 4.83e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 34% E-Value: 4.37e-19

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_3451 (10%) - MXAN_3450 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 3.82e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_1349 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 36% E-Value: 9.41e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (11%) - MXAN_3450 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 34% E-Value: 9.73e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (11%) - MXAN_4164 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 34% E-Value: 1.40e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_5313 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 34% E-Value: 3.23e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

yedV (11%) - yedW (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 18% Positives: 35% E-Value: 1.61e-17

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

torS (11%) - torR (30%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 18% Positives: 34% E-Value: 1.50e-15

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

MXAN_5211 (13%) - MXAN_7396 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 31% E-Value: 3.03e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_7396 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 31% E-Value: 5.91e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (10%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 31% E-Value: 1.36e-16

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1350 (11%) - MXAN_1680 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 1.72e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (10%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 31% E-Value: 1.90e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_1349 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 35% E-Value: 4.09e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (11%) - MXAN_5995 (29%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 2.32e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (10%) - MXAN_4164 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 3.95e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (11%) - MXAN_5313 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 35% E-Value: 3.23e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - phoP1 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 34% E-Value: 1.23e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (13%) - pilR (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 7.72e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - pilR (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 29% E-Value: 1.50e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_7396 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 30% E-Value: 2.57e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5314 (16%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 1.27e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_6149 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 5.53e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (11%) - pilR (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 1.32e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (11%) - MXAN_7396 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 30% E-Value: 2.84e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (17%) - MXAN_2606 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.72e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5211 (13%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 8.82e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1166 (13%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 3.03e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (10%) - pilR (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 2.84e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (13%) - MXAN_2785 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 4.38e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_2785 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 8.53e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sll1003 (11%) - slr1909 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 27% E-Value: 2.10e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1393 (12%) - slr1037 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 27% E-Value: 5.53e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_1350 (11%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 1.50e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7398 (10%) - MXAN_6149 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 7.47e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_7143 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 3.71e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 7.47e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5314 (16%) - MXAN_4645 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 6.11e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_2785 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 3.71e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (17%) - MXAN_2785 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 4.10e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (11%) - MXAN_2785 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 3.71e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_7363 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 1.23e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 1.46e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sll0474 (11%) - slr1400 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 26% E-Value: 3.96e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

glnL (12%) - glnG (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 1.78e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Salinas P et al. (2003)

MXAN_5211 (13%) - MXAN_0460 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 2.84e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (10%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 3.24e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (13%) - MXAN_4645 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 24% E-Value: 4.23e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_4645 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 25% E-Value: 8.25e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (11%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 25% E-Value: 8.25e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7363 (11%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 25% E-Value: 7.47e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_7363 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 5.35e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (11%) - MXAN_7363 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 5.92e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (13%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 24% E-Value: 7.47e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

regS (10%) - regR (14%) (Bradyrhizobium japonicum)

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 4.84e-06

Method	DB Source	Type	Publication
affinity chromatography technology		physical association	Emmerich R et al. (1999)

slr2098 (10%) - slr2100 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 23% E-Value: 1.46e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_1350 (11%) - MXAN_0460 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 4.84e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_0460 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 2.40e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (11%) - MXAN_4645 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 23% E-Value: 7.22e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (10%) - MXAN_7363 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 1.67e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (10%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 1.97e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1228 (11%) - sll1229 (12%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 3.03e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sasA (10%) - sll1291 (12%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 22% E-Value: 2.32e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_7398 (10%) - MXAN_0460 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 7.47e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (10%) - MXAN_4645 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 22% E-Value: 1.12e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (11%) - MXAN_4645 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 24% E-Value: 3.96e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

kinA (9%) - spo0F (11%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 10% Positives: 21% E-Value: 1.12e-06

Method	DB Source	Type	Publication
genetic interference		physical association	Stephenson SJ et al. (2002)

Domain-Domain Interactions (1)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID	predicted interaction	Response_reg	HisKA

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