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The Microbial Protein Interaction Database

Interaction Evidences

cheY - cheB ( Salmonella typhimurium )

Protein A	Protein B
P0A2D5 Chemotaxis protein cheY cheY STM1916	P04042 Chemotaxis response regulator protein-glutamate methylesterase cheB STM1917
CMR Search...	CMR Search...
GO MF: magnesium ion binding GO MF: two-component response regulator activity GO CC: cytoplasm GO BP: ciliary or flagellar motility GO BP: chemotaxis GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: two-component response regulator activity GO MF: protein-glutamate methylesterase activity GO CC: cytoplasm GO BP: chemotaxis GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p... GO BP: sensory perception of chemical stimulus

List of evidences (30)

Experiments (1)

Method	DB Source	Type	Publication
unspecified method		physical association	Ninfa EG et al. (1991)

Interologs (27)

MXAN_2606 (24%) - cheB1 (41%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 47% E-Value: 7.72e-37

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheY (42%) - HP_0392 (9%) (Helicobacter pylori (Campylobacter pylori))

Geometric mean of BLAST Identity: 20% Positives: 32% E-Value: 2.58e-16

Method

DB Source

Type

Publication

two hybrid

physical association

Rain JC et al. (2001)

ompR (28%) - phoB (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 20% Positives: 31% E-Value: 4.41e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_0460 (25%) - MXAN_4072 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 34% E-Value: 5.58e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoB (14%) - phoB (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 19% Positives: 33% E-Value: 7.04e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2606 (24%) - MXAN_4072 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 32% E-Value: 3.27e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (24%) - MXAN_4072 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 32% E-Value: 2.86e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (13%) - MXAN_4164 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 29% E-Value: 3.38e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1905 (26%) - slr1305 (12%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 5.21e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

cpxR (11%) - cpxR (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 7.53e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2785 (24%) - MXAN_4164 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 7.28e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (24%) - MXAN_4164 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 8.32e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP (10%) - phoP (27%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 6.59e-08

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

ompR (10%) - ompR (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 4.88e-07

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

pilR (28%) - MXAN_5313 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 1.85e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoB (27%) - ompR (10%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 16% Positives: 28% E-Value: 7.78e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_0460 (10%) - MXAN_0460 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 4.72e-06

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4645 (24%) - MXAN_5313 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 1.62e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

HP_0392 (27%) - cheY (9%) (Helicobacter pylori (Campylobacter pylori))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.12e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Rain JC et al. (2001)

kdpE (26%) - rstA (9%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 4.72e-06

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

slr1305 (21%) - sll1905 (9%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 8.32e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcB (22%) - hnr (9%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 1.24e-06

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

MXAN_2606 (24%) - MXAN_6149 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 7.28e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (28%) - MXAN_5995 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 2.42e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (24%) - MXAN_5995 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 2.12e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (24%) - MXAN_5995 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 24% E-Value: 2.12e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (24%) - MXAN_5995 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 1.85e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (2)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	CheB_methylest

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