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The Microbial Protein Interaction Database

Interaction Evidences

TP_0519 - TP_0519 ( Treponema pallidum )

Protein A	Protein B
O83532 Response regulatory protein (AtoC) TP_0519	O83532 Response regulatory protein (AtoC) TP_0519
CMR Search...	CMR Search...
GO MF: transcription factor binding GO MF: transcription factor activity GO MF: nucleoside-triphosphatase activity GO MF: ATP binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: transcription factor binding GO MF: transcription factor activity GO MF: nucleoside-triphosphatase activity GO MF: ATP binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (121)

Experiments (1)

Method

DB Source

Type

Publication

two hybrid array

physical association

Titz B et al. (2008)

Interologs (116)

glnG (38%) - glnG (38%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 38% Positives: 60% E-Value: 3.30e-86

Method	DB Source	Type	Publication
two hybrid		physical association	Salinas P et al. (2003)

fhlA (33%) - fhlA (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 46% E-Value: 5.29e-68

Method	DB Source	Type	Publication
enzymatic study		physical association	Leonhartsberger S et al. (2000)

nifA1 (28%) - nifA1 (28%) (Rhodobacter capsulatus (Rhodopseudomonas capsulata))

Geometric mean of BLAST Identity: 28% Positives: 38% E-Value: 9.66e-62

Method	DB Source	Type	Publication
two hybrid		physical association	Pawlowski A et al. (2003)

hrpS (22%) - hrpR (24%) (Pseudomonas syringae pv tomato)

Geometric mean of BLAST Identity: 23% Positives: 36% E-Value: 9.70e-46

Method	DB Source	Type	Publication
two hybrid		physical association	Hutcheson SW et al. (2001)

hrpR (24%) - hrpS (22%) (Pseudomonas syringae pv tomato)

Geometric mean of BLAST Identity: 23% Positives: 36% E-Value: 9.70e-46

Method	DB Source	Type	Publication
two hybrid		physical association	Hutcheson SW et al. (2001)

pilR (39%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 30% E-Value: 7.94e-48

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (11%) - pilR (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 30% E-Value: 7.94e-48

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (38%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 30% E-Value: 4.50e-47

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (11%) - MXAN_5853 (38%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 30% E-Value: 4.50e-47

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilR (39%) - MXAN_5995 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 8.78e-47

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (39%) - MXAN_3450 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 5.69e-46

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (8%) - pilR (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 8.78e-47

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - pilR (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 5.69e-46

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (8%) - pilR (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 29% E-Value: 8.78e-47

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (39%) - MXAN_1680 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 29% E-Value: 8.78e-47

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (8%) - MXAN_7143 (38%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 7.19e-45

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (38%) - MXAN_4645 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 7.19e-45

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (9%) - pilR (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 1.00e-46

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (39%) - MXAN_5313 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 1.00e-46

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (38%) - MXAN_3450 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 3.23e-45

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (38%) - MXAN_6149 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 1.89e-45

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (7%) - MXAN_5853 (38%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 1.89e-45

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - MXAN_5853 (38%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 3.23e-45

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_7143 (38%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 2.73e-44

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (38%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 2.73e-44

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (38%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 3.69e-45

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (38%) - MXAN_4245 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 9.70e-46

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4245 (7%) - MXAN_5853 (38%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 9.70e-46

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_5853 (38%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 3.69e-45

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (11%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 9.17e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoB (10%) - phoB (10%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 1.41e-12

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_1349 (9%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 3.37e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (11%) - MXAN_1349 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 3.37e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fixJ (9%) - fixJ (9%) (Rhizobium meliloti (Sinorhizobium meliloti))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 1.28e-13

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Gouet P et al. (1999)

sll0797 (9%) - sll0797 (9%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.24e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1905 (9%) - slr1305 (9%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.98e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (9%) - sll1905 (9%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.98e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

phoP (9%) - phoP (9%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 1.41e-12

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

yedW (9%) - yedW (9%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 4.40e-14

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

qseB (9%) - qseB (9%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 5.03e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (9%) - yedW (9%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 8.86e-15

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (9%) - cusR (9%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 1.79e-15

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

yedW (9%) - cusR (9%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 8.86e-15

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2606 (11%) - MXAN_5995 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.01e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (8%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.01e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (7%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 6.57e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (11%) - cheB1 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 6.57e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 6.57e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (11%) - MXAN_3450 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 6.57e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_6149 (7%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 3.85e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (11%) - MXAN_6149 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 3.85e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (9%) - MXAN_0460 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 5.19e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 7.51e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (11%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 7.51e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4645 (8%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.98e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (11%) - MXAN_4645 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.98e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 4.87e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (11%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 4.87e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4164 (8%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 7.76e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (11%) - MXAN_4164 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 7.76e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr2104 (7%) - slr1305 (9%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 2.42e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (9%) - slr2104 (7%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 2.42e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2024 (8%) - slr2024 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 6.80e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll0649 (8%) - sll1592 (7%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.79e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1592 (7%) - sll0649 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.79e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1760 (9%) - slr1759 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 2.34e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (8%) - slr1760 (9%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 2.34e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

cpxR (8%) - cpxR (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 2.26e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

torR (8%) - torR (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 4.26e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (10%) - ompR (6%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 2.58e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (6%) - phoB (10%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 2.58e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

arcA (8%) - arcA (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 4.55e-11

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

arcB (7%) - hnr (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.05e-07

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

hnr (8%) - arcB (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.05e-07

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

kdpE (9%) - creB (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 2.50e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

creB (7%) - kdpE (9%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 2.50e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_3450 (8%) - MXAN_3450 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 4.71e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (8%) - MXAN_3450 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 7.26e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - MXAN_1680 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 7.26e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (8%) - MXAN_5995 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 2.18e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (8%) - MXAN_4645 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 2.18e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_5995 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 5.38e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_3450 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 3.49e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_4645 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.05e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (8%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 5.38e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (8%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.05e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 3.49e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 2.58e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (6%) - MXAN_2606 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 4.87e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (11%) - MXAN_7363 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 4.87e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4245 (7%) - MXAN_0460 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 4.70e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (9%) - MXAN_4245 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 4.70e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (8%) - MXAN_1680 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 8.58e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (8%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 4.12e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (8%) - MXAN_4164 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 6.57e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_4164 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 4.12e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (8%) - MXAN_4164 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 8.58e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (9%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 9.49e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (9%) - MXAN_4645 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 2.50e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (8%) - MXAN_5313 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 2.50e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_5313 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 9.49e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheY (7%) - HP_0392 (7%) (Helicobacter pylori (Campylobacter pylori))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 2.34e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Rain JC et al. (2001)

HP_0392 (7%) - cheY (7%) (Helicobacter pylori (Campylobacter pylori))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 2.34e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Rain JC et al. (2001)

arcB (7%) - cheY (7%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 1.98e-06

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

cheY (7%) - arcB (7%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 1.98e-06

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

creB (7%) - creB (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 1.37e-07

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoP (7%) - phoP (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 7% Positives: 14% E-Value: 7.26e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)
molecular sieving		physical association	Bachhawat P et al. (2007)
x-ray crystallography		physical association	Bachhawat P et al. (2007)

phoP2 (7%) - MXAN_6149 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 3.15e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (7%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 3.15e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 6.15e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (6%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 2.58e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_7363 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 2.58e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4245 (7%) - MXAN_4245 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 4.26e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (9%) - MXAN_7363 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 6.15e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (6%) - MXAN_5313 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 6.15e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

ompR (6%) - ompR (6%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 13% E-Value: 4.71e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

Domain-Domain Interactions (4)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Sigma54_activat
structural domain contact	3DID,iPfam	predicted interaction	Sigma54_activat	Sigma54_activat
structural domain contact	iPfam	predicted interaction	HTH_8	HTH_8

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