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The Microbial Protein Interaction Database

Interaction Evidences

sasA - sll1291 ( Synechocystis sp (strain PCC 6803) )

Protein A	Protein B
Q55630 Adaptive-response sensory-kinase sasA sasA sll0750	P73176 PatA subfamily sll1291
CMR Search...	CMR Search...
GO MF: two-component sensor activity GO MF: ATP binding GO CC: membrane GO BP: circadian rhythm GO BP: peptidyl-histidine phosphorylation GO BP: two-component signal transduction system (p...	GO MF: two-component response regulator activity GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (143)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

Interologs (141)

sasA (96%) - slr1594 (31%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 55% Positives: 71% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sphS (18%) - slr1594 (31%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 24% Positives: 39% E-Value: 1.63e-42

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (16%) - slr1594 (31%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 22% Positives: 40% E-Value: 4.58e-41

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1147 (19%) - slr1783 (10%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 7.36e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

phoR1 (18%) - MXAN_2785 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 1.75e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (16%) - MXAN_4164 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 3.19e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (17%) - MXAN_4164 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 4.93e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (16%) - MXAN_4164 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 4.03e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1003 (16%) - slr1909 (10%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 2.14e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1228 (18%) - sll1229 (10%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 6.88e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1905 (17%) - slr1305 (10%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 1.10e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1353 (17%) - sll1905 (10%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 2.53e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

slr0210 (17%) - slr1909 (10%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 9.94e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1393 (21%) - slr1037 (7%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 4.77e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr0533 (18%) - sll0649 (9%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 1.75e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2098 (15%) - slr2100 (10%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 1.18e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

yycG (17%) - yycF (9%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 4.03e-17

Method	DB Source	Type	Publication
enzymatic study		physical association	Fukuchi K et al. (2000)

glnL (18%) - glnG (9%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 1.88e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Salinas P et al. (2003)

pleC (19%) - divK (8%) (Brucella abortus - Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 7.11e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Hallez R et al. (2007)

pleC (19%) - divK (8%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 1.58e-17

Method

DB Source

Type

Publication

dephosphorylation

phosphorylation

pleC (19%) - pleD (8%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 8.99e-17

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

phoR2 (17%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 2.53e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 2.07e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (15%) - MXAN_2785 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 2.80e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (15%) - MXAN_2785 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 1.70e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (16%) - MXAN_2785 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 3.91e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (10%) - MXAN_2785 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 5.45e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (16%) - MXAN_2785 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 4.47e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7363 (17%) - MXAN_2785 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 4.77e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (15%) - MXAN_4164 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 2.53e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (16%) - MXAN_4164 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 3.53e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4165 (15%) - MXAN_4164 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 1.34e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5996 (14%) - MXAN_4164 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 4.77e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (16%) - frzZ (8%) (Myxococcus xanthus (strain DK 1622) - Myxococcus xanthus)

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 1.14e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

cpxA (16%) - cpxR (9%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 5.10e-12

Method	DB Source	Type	Publication
unspecified method		physical association	Nakayama S et al. (2003)

sll0474 (19%) - slr1400 (7%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 2.99e-16

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

sll1229 (16%) - sll1228 (9%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 2.14e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2104 (16%) - slr1305 (10%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 2.37e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

creC (16%) - creB (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 3.09e-13

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

kdpD (19%) - kdpE (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 5.45e-18

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Luttmann D et al. (2009)
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)
enzymatic study		physical association	Heermann R et al. (2003)
protein kinase assay		physical association	Luttmann D et al. (2009)

torS (17%) - torR (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 1.26e-10

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

divJ (16%) - divK (8%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 1.43e-14

Method

DB Source

Type

Publication

protein kinase assay

phosphorylation

Paul R et al. (2008)

divJ (16%) - pleD (8%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 8.14e-14

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

MXAN_2606 (16%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 5.10e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (16%) - MXAN_5995 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 4.47e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 1.34e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5211 (16%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 4.47e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (15%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 3.31e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (15%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 2.00e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (16%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 4.62e-13

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (16%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 5.27e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5314 (15%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 9.62e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (16%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 3.78e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilS (16%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 3.91e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1350 (16%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 1.69e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoR2 (17%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 2.45e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (17%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 6.45e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoR3 (16%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 3.78e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (16%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 3.91e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 5.27e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - phoP3 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 2.53e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (16%) - MXAN_4645 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 1.14e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (15%) - MXAN_4645 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 5.45e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5314 (15%) - MXAN_4645 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 2.62e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (16%) - MXAN_4645 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 1.26e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (16%) - MXAN_4645 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 1.43e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1350 (16%) - MXAN_4645 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 1.81e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (17%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 6.23e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (17%) - MXAN_5995 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 5.45e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (17%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 1.64e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (17%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 6.44e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (17%) - MXAN_4645 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 1.75e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (17%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 1.43e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - MXAN_5313 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 6.02e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5996 (14%) - MXAN_2785 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 5.28e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (17%) - MXAN_5995 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 2.00e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pdhS (15%) - divK (8%) (Brucella abortus)

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 4.93e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Hallez R et al. (2007)

phoQ (15%) - phoP (7%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 9.31e-10

Method	DB Source	Type	Publication
far western blotting		physical association	Chamnongpol S et al. (2000)
surface plasmon resonance		physical association	Castelli ME et al. (2003)

prrB (15%) - prrA (9%) (Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 8.42e-11

Method	DB Source	Type	Publication
enzymatic study		direct interaction	Nowak E et al. (2006)

arcB (14%) - cheY (8%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 2.89e-11

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

yedV (15%) - yedW (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 7.37e-11

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

basS (15%) - basR (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 3.00e-08

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

MXAN_7059 (15%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 3.20e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (15%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 8.42e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (15%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 5.10e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (16%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 1.18e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (15%) - phoP3 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 2.45e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5314 (15%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 2.45e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (16%) - frzS (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 1.30e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilS (16%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 9.95e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1350 (16%) - frzS (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 1.64e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (16%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 9.95e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sdeK (14%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 2.89e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sdeK (14%) - MXAN_5995 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 22% E-Value: 2.53e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (14%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 7.62e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sdeK (14%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 2.99e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1166 (15%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.07e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (16%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 5.10e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - MXAN_1349 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 22% E-Value: 3.42e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (16%) - MXAN_1349 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 8.70e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (16%) - MXAN_5889 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 1.34e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (16%) - MXAN_5889 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 1.26e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (15%) - MXAN_5212 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 3.54e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (10%) - MXAN_4164 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 15% E-Value: 1.18e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (17%) - MXAN_5313 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 1.64e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (16%) - MXAN_5313 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 1.14e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (16%) - MXAN_5313 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 1.14e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (14%) - MXAN_5313 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 8.70e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5996 (14%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 6.04e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5996 (14%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 1.59e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5996 (14%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 6.24e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - phoP1 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 22% E-Value: 7.86e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

BruAb1_0598 (13%) - divK (8%) (Brucella abortus)

Geometric mean of BLAST Identity: 10% Positives: 21% E-Value: 6.03e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Hallez R et al. (2007)

slr0210 (17%) - sll1624 (5%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 3.42e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

kdpD (15%) - A2VGV6 (7%) (Mycobacterium tuberculosis C - Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 4.47e-12

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Davey CA et al. (2002)

phoQ (13%) - phoP (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 6.04e-09

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

envZ (14%) - ompR (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 1.18e-08

Method	DB Source	Type	Publication
electrophoretic mobility shift assay		physical association	Harlocker SL et al. (1995)
far western blotting		physical association	Cai SJ et al. (2002)
pull down		physical association	Cai SJ et al. (2002)

MXAN_7206 (10%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 14% E-Value: 1.54e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7206 (10%) - MXAN_4645 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 14% E-Value: 4.18e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (10%) - MXAN_2785 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 1.30e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - MXAN_7363 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 2.53e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (17%) - MXAN_7363 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 7.87e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (9%) - MXAN_4164 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 7.87e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5996 (14%) - MXAN_5212 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 6.67e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

A3ZCK1 (14%) - Cj1227c (7%) (Campylobacter jejuni - Campylobacter jejuni subsp jejuni HB93-13)

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 6.46e-07

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Svensson SL et al. (2009)

MXAN_6688 (9%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 9.96e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (9%) - MXAN_5995 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 8.71e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (9%) - MXAN_7396 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 1.03e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (10%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 3.91e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7206 (10%) - MXAN_5889 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 4.94e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (9%) - MXAN_2785 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 8.71e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3606 (10%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 6.24e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_3606 (10%) - MXAN_5212 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 2.62e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (16%) - MXAN_7363 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 18% E-Value: 5.10e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (16%) - MXAN_7363 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 17% E-Value: 6.45e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (9%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 2.62e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_6688 (9%) - frzS (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 2.54e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (9%) - MXAN_1349 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 16% E-Value: 1.70e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (9%) - MXAN_5889 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 3.31e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (10%) - MXAN_7363 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 1.88e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (9%) - MXAN_7363 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 1.26e-06

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

Domain-Domain Interactions (1)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID	predicted interaction	Response_reg	HisKA

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