The Microbial Protein Interaction Database

physical association

MXAN_4072 (31%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 5.41e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1708 (37%) - slr1805 (12%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 2.34e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

fruA (29%) - MXAN_1350 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 2.27e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (27%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 1.99e-13

Method

DB Source

Type

Publication

physical association

slr1584 (26%) - sll1475 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 20% Positives: 30% E-Value: 8.95e-10

Method

DB Source

Type

Publication

physical association

slr1584 (26%) - CcaS (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 20% Positives: 30% E-Value: 8.95e-10

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation reaction	Hirose Y et al. (2008)

MXAN_5995 (23%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 32% E-Value: 1.69e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (23%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 2.28e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

bvgA (23%) - bvgS (15%) (Bordetella pertussis)

Geometric mean of BLAST Identity: 19% Positives: 35% E-Value: 1.38e-14

Method	DB Source	Type	Publication
genetic interference		physical association	Merkel TJ et al. (2003)

slr1909 (25%) - slr0210 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 9.56e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

fruA (29%) - MXAN_4165 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 33% E-Value: 1.09e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (27%) - pilS (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 1.86e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (27%) - phoR1 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 33% E-Value: 2.97e-13

Method

DB Source

Type

Publication

physical association

MXAN_1349 (21%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 30% E-Value: 3.29e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (23%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 1.74e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (23%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 34% E-Value: 2.35e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (31%) - MXAN_0459 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 32% E-Value: 3.63e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0789 (24%) - sll0790 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 18% Positives: 31% E-Value: 2.78e-11

Method

DB Source

Type

Publication

physical association

prrA (24%) - prrB (13%) (Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 18% Positives: 31% E-Value: 2.60e-09

Method	DB Source	Type	Publication
enzymatic study		direct interaction	Nowak E et al. (2006)

creB (27%) - creC (12%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 18% Positives: 29% E-Value: 6.00e-10

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

MXAN_6149 (31%) - MXAN_7398 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 29% E-Value: 8.64e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP3 (24%) - phoR1 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 33% E-Value: 1.09e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (31%) - MXAN_6688 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 31% E-Value: 1.02e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (31%) - MXAN_7398 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 1.99e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cpxR (26%) - cpxA (11%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 17% Positives: 29% E-Value: 1.06e-06

Method	DB Source	Type	Publication
unspecified method		physical association	Nakayama S et al. (2003)

slr1909 (25%) - sll1003 (12%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 32% E-Value: 3.08e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_3450 (16%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 26% E-Value: 8.37e-12

Method

DB Source

Type

Publication

physical association

phoP2 (27%) - MXAN_7398 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 7.58e-09

Method

DB Source

Type

Publication

physical association

MXAN_1349 (21%) - phoR1 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 29% E-Value: 4.91e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (23%) - MXAN_4165 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 33% E-Value: 1.75e-09

Method

DB Source

Type

Publication

physical association

MXAN_5313 (17%) - MXAN_7363 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 3.63e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0649 (15%) - slr0533 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 1.80e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

yycF (21%) - yycG (12%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 16% Positives: 30% E-Value: 1.29e-08

Method	DB Source	Type	Publication
enzymatic study		physical association	Fukuchi K et al. (2000)

evgA (19%) - evgS (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 16% Positives: 32% E-Value: 3.76e-12

Method	DB Source	Type	Publication
surface plasmon resonance		physical association	Perraud AL et al. (2000)
surface plasmon resonance		physical association	Tanabe H et al. (1998)

zraR (20%) - zraS (13%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 4.29e-12

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

fruA (29%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 4.02e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (17%) - MXAN_1350 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 2.87e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (27%) - MXAN_6688 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 28% E-Value: 3.89e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (31%) - MXAN_3451 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 1.13e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (16%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 8.65e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (15%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 28% E-Value: 7.32e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (23%) - MXAN_7398 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 8.66e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (23%) - MXAN_5996 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 9.90e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (23%) - MXAN_0459 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 1.17e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0797 (16%) - slr1147 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 4.02e-10

Method

DB Source

Type

Publication

physical association

slr1305 (15%) - slr2104 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 6.85e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

pleD (16%) - pleC (14%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 2.98e-09

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

MXAN_5995 (23%) - MXAN_6688 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 3.29e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (14%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 3.76e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (31%) - asgD (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 1.25e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (27%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 5.61e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (16%) - MXAN_1350 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 1.21e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (16%) - phoR1 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 1.25e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (17%) - phoR1 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 2.69e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (29%) - MXAN_3451 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 3.08e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (15%) - phoR1 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.09e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (15%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 7.57e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (23%) - MXAN_6688 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 29% E-Value: 4.44e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (17%) - pilS (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 6.20e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (17%) - phoR1 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 9.89e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0797 (16%) - sll0798 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 8.95e-10

Method

DB Source

Type

Publication

physical association

slr1305 (15%) - sll1905 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 1.75e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1760 (15%) - slr1759 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 6.63e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

glnG (14%) - glnL (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 8.38e-08

Method

DB Source

Type

Publication

physical association

Salinas P et al. (2003)

fruA (29%) - asgD (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 7.83e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (16%) - pilS (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 7.83e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (14%) - MXAN_1350 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 5.99e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (17%) - MXAN_7398 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 6.85e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (27%) - asgD (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 1.09e-07

Method

DB Source

Type

Publication

physical association

MXAN_1680 (16%) - pilS (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 7.09e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (27%) - MXAN_3451 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 4.30e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (21%) - MXAN_6688 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 6.42e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (23%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 27% E-Value: 6.42e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (16%) - MXAN_5996 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 3.29e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (17%) - MXAN_0459 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 1.25e-11

Method

DB Source

Type

Publication

physical association

ompR (14%) - envZ (12%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 25% E-Value: 2.06e-06

Method	DB Source	Type	Publication
electrophoretic mobility shift assay		physical association	Harlocker SL et al. (1995)
far western blotting		physical association	Cai SJ et al. (2002)
pull down		physical association	Cai SJ et al. (2002)

pleD (16%) - divJ (11%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 13% Positives: 24% E-Value: 1.34e-09

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

phoP3 (24%) - asgD (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 4.02e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (17%) - MXAN_6688 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 3.52e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (15%) - MXAN_7398 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 2.79e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (14%) - MXAN_6688 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 7.33e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (16%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 2.36e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (14%) - MXAN_7398 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 1.43e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (17%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 5.08e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (16%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 2.13e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (15%) - MXAN_6688 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 23% E-Value: 1.43e-07

Method

DB Source

Type

Publication

physical association