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The Microbial Protein Interaction Database

Interaction Evidences

MXAN_7143 - asgD ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1CWG7 Sigma-54 dependent DNA-binding response regulator MXAN_7143	Q1CWW4 Sensor protein asgD MXAN_6996
CMR Search...	CMR Search...
GO MF: transcription factor binding GO MF: transcription factor activity GO MF: nucleoside-triphosphatase activity GO MF: ATP binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: two-component sensor activity GO MF: ATP binding GO MF: two-component response regulator activity GO CC: membrane GO BP: regulation of transcription, DNA-dependent GO BP: peptidyl-histidine phosphorylation GO BP: two-component signal transduction system (p...

List of evidences (119)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (115)

pilR (41%) - asgD (87%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 60% Positives: 69% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

nla28 (39%) - asgD (87%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 59% Positives: 68% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (94%) - sdeK (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 37% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - asgD (87%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 33% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (40%) - MXAN_7398 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 38% E-Value: 1.17e-61

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (94%) - phoR1 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 33% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - asgD (87%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 33% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - asgD (87%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 32% E-Value: 0

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4645 (6%) - asgD (87%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 32% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (94%) - MXAN_4645 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 26% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (94%) - phoP2 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 26% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (40%) - sdeK (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 29% E-Value: 2.98e-57

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (40%) - MXAN_0459 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 25% E-Value: 3.54e-46

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (41%) - MXAN_1350 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 3.78e-44

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

glnG (6%) - glnG (38%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 1.94e-44

Method	DB Source	Type	Publication
two hybrid		physical association	Salinas P et al. (2003)

pilR (41%) - MXAN_2606 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 9.00e-46

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (41%) - MXAN_3450 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 20% E-Value: 2.90e-44

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (41%) - MXAN_1680 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 7.88e-46

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (41%) - MXAN_5313 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 20% E-Value: 6.24e-47

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (40%) - MXAN_2606 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 3.66e-47

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5853 (40%) - MXAN_3450 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 20% E-Value: 1.18e-45

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (41%) - MXAN_5995 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 1.49e-44

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (10%) - MXAN_7398 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 1.00e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (40%) - phoP2 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 1.18e-45

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (13%) - MXAN_7059 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 2.55e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_7398 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 2.39e-22

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4645 (6%) - MXAN_7398 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 3.12e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_7059 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 14% E-Value: 1.71e-20

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1680 (13%) - MXAN_1350 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 8.24e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (9%) - sdeK (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 1.11e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (10%) - sdeK (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 7.68e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1529 (16%) - sll1672 (5%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 4.36e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_3450 (8%) - MXAN_7059 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 2.55e-20

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (8%) - sdeK (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.07e-18

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_7059 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 3.94e-21

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1680 (13%) - MXAN_4164 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 5.16e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (10%) - MXAN_7363 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 1.27e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (10%) - MXAN_0459 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 3.03e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

yycF (8%) - yycG (7%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 3.82e-08

Method	DB Source	Type	Publication
enzymatic study		physical association	Fukuchi K et al. (2000)

kdpE (8%) - kdpD (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 1.55e-09

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Luttmann D et al. (2009)
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)
enzymatic study		physical association	Heermann R et al. (2003)
protein kinase assay		physical association	Luttmann D et al. (2009)

MXAN_2606 (8%) - MXAN_1350 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 5.52e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_0460 (10%) - MXAN_1350 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.31e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (7%) - MXAN_0460 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 3.69e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1680 (13%) - MXAN_3450 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 6.31e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (13%) - pilR (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 6.31e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - phoR1 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 4.37e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - phoR1 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 2.93e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (10%) - phoR1 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 6.97e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - sdeK (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 6.08e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (8%) - phoR1 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 1.01e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - phoR1 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 6.74e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (9%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 5.90e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 8.52e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 1.31e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 5.71e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_7363 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 4.08e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_7363 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 1.77e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (10%) - phoR1 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 2.10e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (9%) - MXAN_0459 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.31e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP1 (8%) - phoR1 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 8.52e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1905 (8%) - slr1305 (6%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 3.82e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2100 (8%) - slr2098 (7%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 2.93e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

phoP (5%) - phoP (9%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 2.65e-09

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

cpxR (5%) - cpxR (9%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 1.77e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cheY (8%) - arcB (6%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 4.23e-07

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

MXAN_5995 (9%) - MXAN_2606 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 1.36e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (5%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 1.31e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (8%) - cheB1 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 2.83e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_3450 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 4.23e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5995 (9%) - pilR (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 4.37e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - phoR1 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 1.66e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4645 (6%) - MXAN_1350 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 4.09e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (9%) - MXAN_4645 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 1.04e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (6%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 4.23e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_4164 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 7.96e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_4164 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 3.46e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (10%) - phoP2 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 3.03e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (10%) - pilR (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 3.03e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (10%) - MXAN_4645 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 7.20e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0797 (4%) - sll0797 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.45e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1229 (8%) - sll1228 (5%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 11% E-Value: 6.52e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (7%) - slr2104 (5%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 12% E-Value: 5.33e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1905 (8%) - sll1353 (4%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 11% E-Value: 2.93e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

slr1305 (7%) - sll1905 (6%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 12% E-Value: 2.24e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll0649 (7%) - slr0533 (5%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 11% E-Value: 5.52e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

yedW (5%) - yedW (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 2.48e-07

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (4%) - ompR (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.01e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (7%) - ompR (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 8.80e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (7%) - phoB (5%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 2.56e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (5%) - phoB (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 2.24e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (7%) - yedW (5%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 4.37e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

yedW (7%) - cusR (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 4.09e-06

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2606 (8%) - MXAN_5995 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 2.17e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - MXAN_2606 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.96e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_3450 (5%) - MXAN_3450 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 6.31e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_7143 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 11% E-Value: 2.83e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_2606 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 7.45e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (8%) - phoP2 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 4.23e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_3450 (8%) - pilR (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 6.31e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - pilR (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 11% E-Value: 4.23e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - MXAN_1680 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.72e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (6%) - MXAN_7143 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 11% E-Value: 3.70e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (6%) - MXAN_2606 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 9.73e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_4645 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.01e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1349 (8%) - MXAN_2606 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 11% E-Value: 4.52e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_1349 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 2.93e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_5995 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 4.99e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_2606 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 11% E-Value: 3.03e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_3450 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 9.73e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_4645 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 2.32e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (6%) - MXAN_5313 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 6.74e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_5313 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 5.16e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cusR (4%) - cusR (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 7.21e-07

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoP2 (4%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 2.40e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (6%) - MXAN_5995 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 10% E-Value: 1.61e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (3)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Sigma54_activat
structural domain contact	3DID	predicted interaction	Response_reg	HisKA

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