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The Microbial Protein Interaction Database

Interaction Evidences

asgD - MXAN_6149 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1CWW4 Sensor protein asgD MXAN_6996	Q1CZ93 DNA-binding response regulator, LuxR family MXAN_6149
CMR Search...	CMR Search...
GO MF: two-component sensor activity GO MF: ATP binding GO MF: two-component response regulator activity GO CC: membrane GO BP: regulation of transcription, DNA-dependent GO BP: peptidyl-histidine phosphorylation GO BP: two-component signal transduction system (p...	GO MF: transcription factor activity GO MF: sequence-specific DNA binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (28)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (24)

asgD (87%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 42% Positives: 53% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (18%) - MXAN_6149 (93%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 41% Positives: 49% E-Value: 1.31e-72

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (5%) - MXAN_6149 (93%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 29% E-Value: 4.08e-58

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (18%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 35% E-Value: 1.67e-27

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (4%) - MXAN_6149 (93%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 26% E-Value: 1.31e-56

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (18%) - MXAN_0460 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 1.24e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (11%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 3.49e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

bvgS (8%) - bvgA (27%) (Bordetella pertussis)

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 9.52e-15

Method	DB Source	Type	Publication
genetic interference		physical association	Merkel TJ et al. (2003)

MXAN_0460 (7%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 6.17e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 2.27e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (8%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 5.06e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

evgS (6%) - evgA (25%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 5.78e-12

Method	DB Source	Type	Publication
surface plasmon resonance		physical association	Perraud AL et al. (2000)
surface plasmon resonance		physical association	Tanabe H et al. (1998)

arcB (6%) - hnr (24%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 3.75e-07

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

MXAN_1350 (7%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.13e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (5%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 5.23e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0649 (5%) - sll1592 (29%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 9.21e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_1350 (7%) - MXAN_0460 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 1.63e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - MXAN_0460 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 8.63e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (4%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 1.68e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (8%) - MXAN_0460 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 3.75e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5995 (5%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 4.43e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (5%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 2.68e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_3450 (5%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 8.63e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (16%) - MXAN_0460 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 4.58e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

Domain-Domain Interactions (3)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID	predicted interaction	Response_reg	GerE
structural domain contact	3DID	predicted interaction	Response_reg	HisKA

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