The Microbial Protein Interaction Database

physical association

frzS (79%) - MXAN_6688 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 29% Positives: 36% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (7%) - MXAN_1350 (97%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 34% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pleD (9%) - pleC (18%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 5.46e-19

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

MXAN_5313 (8%) - phoR1 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.75e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (8%) - MXAN_7363 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 2.99e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP1 (8%) - phoR1 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 3.42e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

prrA (8%) - prrB (15%) (Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 1.35e-13

Method	DB Source	Type	Publication
enzymatic study		direct interaction	Nowak E et al. (2006)

pleD (9%) - divJ (15%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.71e-18

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

MXAN_5995 (7%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 1.18e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

aglZ (7%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 1.70e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 5.10e-21

Method

DB Source

Type

Publication

physical association

phoP2 (7%) - MXAN_7398 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 3.42e-17

Method

DB Source

Type

Publication

physical association

phoP2 (7%) - phoR3 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 6.46e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP3 (6%) - phoR1 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 2.99e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - phoR1 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.99e-21

Method

DB Source

Type

Publication

physical association

MXAN_4645 (7%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 4.18e-23

Method

DB Source

Type

Publication

physical association

MXAN_5995 (7%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 1.64e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 5.45e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (8%) - phoR3 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 3.79e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0797 (6%) - sll0798 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 3.79e-16

Method

DB Source

Type

Publication

physical association

slr1584 (8%) - sll1475 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 6.25e-15

Method

DB Source

Type

Publication

physical association

sll1905 (6%) - sll1353 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 7.88e-18

Method

DB Source

Type

Publication

physical association

sll0649 (7%) - slr0533 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 4.62e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1584 (8%) - CcaS (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 6.25e-15

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation reaction	Hirose Y et al. (2008)

yycF (6%) - yycG (14%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 1.88e-19

Method	DB Source	Type	Publication
enzymatic study		physical association	Fukuchi K et al. (2000)

divK (5%) - pleC (18%) (Brucella abortus - Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 9.96e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Hallez R et al. (2007)

divK (6%) - pleC (18%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 2.29e-17

Method

DB Source

Type

Publication

dephosphorylation

phosphorylation

aglZ (7%) - MXAN_7398 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 1.14e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - asgD (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 8.17e-11

Method

DB Source

Type

Publication

physical association

phoP2 (7%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 6.25e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - pilS (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 6.68e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - phoR2 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 2.30e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - sdeK (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 5.12e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_3451 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 2.15e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (7%) - MXAN_5314 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 3.66e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (7%) - MXAN_7398 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 2.80e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (6%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 3.91e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (6%) - phoR1 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 2.29e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5889 (7%) - MXAN_7398 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 5.46e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5889 (7%) - phoR3 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 1.03e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (7%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 5.83e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_7059 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 3.92e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_7398 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 3.66e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 7.62e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (8%) - pilS (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 3.92e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (8%) - sdeK (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 3.00e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (7%) - MXAN_0459 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 1.39e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

divK (5%) - BruAb1_0598 (15%) (Brucella abortus)

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 3.66e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Hallez R et al. (2007)

sll0797 (6%) - slr1147 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 1.35e-09

Method

DB Source

Type

Publication

physical association

sll1229 (5%) - sll1228 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 1.82e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

torR (6%) - torS (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 8.73e-13

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

divK (6%) - divJ (15%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 1.14e-16

Method

DB Source

Type

Publication

protein kinase assay

phosphorylation

Paul R et al. (2008)

MXAN_5995 (7%) - MXAN_6688 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 2.63e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

aglZ (7%) - MXAN_6688 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 3.79e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

aglZ (7%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 17% E-Value: 2.08e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP3 (6%) - asgD (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 8.17e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_6688 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.14e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (7%) - sdeK (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 1.18e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (7%) - asgD (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 6.68e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (7%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 5.12e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 6.68e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_4165 (11%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 2.38e-10

Method

DB Source

Type

Publication

physical association

MXAN_4164 (7%) - MXAN_5996 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 2.72e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

aglZ (7%) - MXAN_5996 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 8.44e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

divK (5%) - pdhS (13%) (Brucella abortus)

Geometric mean of BLAST Identity: 8% Positives: 16% E-Value: 2.37e-14

Method

DB Source

Type

Publication

physical association

Hallez R et al. (2007)

sll1291 (5%) - sasA (12%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 2.37e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

aglZ (7%) - MXAN_7206 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.82e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_7206 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 5.48e-07

Method

DB Source

Type

Publication

physical association