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The Microbial Protein Interaction Database

Interaction Evidences

MXAN_7206 - MXAN_4072 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1CWA4 Sensor protein MXAN_7206	Q1D523 DNA-binding response regulator, LuxR family MXAN_4072
CMR Search...	CMR Search...
GO MF: two-component sensor activity GO MF: ATP binding GO MF: two-component response regulator activity GO CC: membrane GO BP: regulation of transcription, DNA-dependent GO BP: peptidyl-histidine phosphorylation GO BP: two-component signal transduction system (p...	GO MF: transcription factor activity GO MF: sequence-specific DNA binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (20)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (16)

MXAN_0459 (6%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 26% E-Value: 2.17e-59

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (6%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 24% E-Value: 9.42e-55

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (6%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 26% E-Value: 2.48e-59

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 24% E-Value: 3.35e-56

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (5%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 22% E-Value: 2.57e-52

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (4%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 21% E-Value: 1.84e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

bvgS (6%) - bvgA (20%) (Bordetella pertussis)

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 1.21e-09

Method	DB Source	Type	Publication
genetic interference		physical association	Merkel TJ et al. (2003)

MXAN_7398 (6%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 2.27e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (6%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 5.97e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (6%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 7.30e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7059 (5%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.33e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (5%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 6.62e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (5%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 7.56e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4165 (4%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.17e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

zraS (5%) - zraR (11%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 4.00e-13

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

MXAN_1350 (3%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 1.17e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (3)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID	predicted interaction	Response_reg	GerE
structural domain contact	3DID	predicted interaction	Response_reg	HisKA

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