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The Microbial Protein Interaction Database

Interaction Evidences

MXAN_2606 - cheB1 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1D948 Sensor protein MXAN_2606	Q1D359 Chemotaxis response regulator protein-glutamate methylesterase 1 cheB1 MXAN_4752
CMR Search...	CMR Search...
GO MF: two-component sensor activity GO MF: ATP binding GO MF: two-component response regulator activity GO CC: membrane GO BP: regulation of transcription, DNA-dependent GO BP: peptidyl-histidine phosphorylation GO BP: two-component signal transduction system (p...	GO MF: two-component response regulator activity GO MF: protein-glutamate methylesterase activity GO CC: cytoplasm GO BP: chemotaxis GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p... GO BP: sensory perception of chemical stimulus

List of evidences (26)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (22)

MXAN_2606 (88%) - MXAN_4164 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 32% Positives: 37% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (7%) - cheB1 (89%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 30% E-Value: 1.31e-95

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - cheB1 (89%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 31% E-Value: 3.13e-93

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7398 (5%) - cheB1 (89%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 26% E-Value: 1.19e-92

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - cheB1 (89%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 25% E-Value: 1.55e-92

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - cheB1 (89%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 25% E-Value: 6.30e-94

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - cheB1 (89%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 24% E-Value: 3.82e-91

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (13%) - MXAN_4164 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 2.99e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheY (3%) - cheB (39%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 2.13e-33

Method	DB Source	Type	Publication
unspecified method		physical association	Ninfa EG et al. (1991)

slr2104 (12%) - slr1305 (10%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 1.94e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_7206 (7%) - MXAN_4164 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 7.38e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1905 (6%) - slr1305 (10%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 10% E-Value: 2.80e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_7398 (5%) - MXAN_4164 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 2.80e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1147 (5%) - slr1783 (10%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 4.95e-06

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

rstA (6%) - kdpE (10%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 8.16e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_7396 (4%) - MXAN_4164 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 3.66e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_4164 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 1.49e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (4%) - MXAN_4164 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 9% E-Value: 9.02e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (12%) - MXAN_4164 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 1.76e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (4%) - MXAN_4164 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 7.63e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

creB (4%) - kdpE (10%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.59e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpD (4%) - kdpE (10%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 8.73e-07

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Luttmann D et al. (2009)
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)
enzymatic study		physical association	Heermann R et al. (2003)
protein kinase assay		physical association	Luttmann D et al. (2009)

Domain-Domain Interactions (3)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID	predicted interaction	Response_reg	HisKA
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	CheB_methylest

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