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The Microbial Protein Interaction Database

Interaction Evidences

MXAN_2606 - MXAN_4072 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1D948 Sensor protein MXAN_2606	Q1D523 DNA-binding response regulator, LuxR family MXAN_4072
CMR Search...	CMR Search...
GO MF: two-component sensor activity GO MF: ATP binding GO MF: two-component response regulator activity GO CC: membrane GO BP: regulation of transcription, DNA-dependent GO BP: peptidyl-histidine phosphorylation GO BP: two-component signal transduction system (p...	GO MF: transcription factor activity GO MF: sequence-specific DNA binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (32)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (28)

MXAN_2606 (88%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 44% Positives: 59% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (88%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 38% Positives: 50% E-Value: 0

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (13%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 32% Positives: 39% E-Value: 4.27e-65

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 29% E-Value: 1.05e-55

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (6%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 28% E-Value: 2.97e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (5%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 24% E-Value: 4.01e-55

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 23% E-Value: 8.93e-55

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 24% E-Value: 2.12e-56

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (4%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 23% E-Value: 4.29e-53

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (4%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 23% E-Value: 2.60e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (4%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 23% E-Value: 8.64e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1805 (7%) - sll1708 (25%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 2.90e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

bvgS (7%) - bvgA (20%) (Bordetella pertussis)

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 3.80e-09

Method	DB Source	Type	Publication
genetic interference		physical association	Merkel TJ et al. (2003)

sll0649 (5%) - sll1592 (25%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 1.35e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1414 (5%) - sll1592 (25%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 1.18e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_1350 (7%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 1.30e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (5%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 9.66e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 1.26e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 2.15e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 7.40e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.54e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 3.11e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (4%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 6.26e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 3.80e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (4%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 3.80e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (4%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 2.01e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (4%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 1.26e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

zraS (5%) - zraR (11%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 5.13e-10

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

Domain-Domain Interactions (3)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID	predicted interaction	Response_reg	HisKA
structural domain contact	3DID	predicted interaction	Response_reg	GerE

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