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The Microbial Protein Interaction Database

Interaction Evidences

MXAN_4072 - MXAN_2785 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1D523 DNA-binding response regulator, LuxR family MXAN_4072	Q1D8M1 Sensor protein MXAN_2785
CMR Search...	CMR Search...
GO MF: transcription factor activity GO MF: sequence-specific DNA binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: two-component sensor activity GO MF: ATP binding GO MF: two-component response regulator activity GO CC: membrane GO BP: regulation of transcription, DNA-dependent GO BP: peptidyl-histidine phosphorylation GO BP: two-component signal transduction system (p...

List of evidences (39)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (34)

MXAN_4072 (80%) - MXAN_2606 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 39% E-Value: 1.96e-72

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 29% E-Value: 1.36e-61

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - MXAN_0459 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 29% E-Value: 2.49e-59

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - MXAN_3451 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 28% E-Value: 2.04e-57

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - phoR2 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 27% E-Value: 6.78e-53

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - MXAN_7206 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 22% E-Value: 1.84e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - phoP2 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 22% E-Value: 1.41e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - MXAN_0460 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 21% E-Value: 1.08e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (22%) - MXAN_2606 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 4.73e-30

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - MXAN_4245 (3%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 21% E-Value: 3.97e-53

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

bvgA (20%) - bvgS (12%) (Bordetella pertussis)

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.63e-26

Method	DB Source	Type	Publication
genetic interference		physical association	Merkel TJ et al. (2003)

MXAN_4072 (80%) - MXAN_6688 (3%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 19% E-Value: 1.32e-52

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - MXAN_5853 (3%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 5.19e-53

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_2606 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 5.78e-28

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sll1708 (25%) - slr1805 (6%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 8.09e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1592 (25%) - slr1414 (6%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 1.80e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_6149 (22%) - asgD (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 3.76e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (22%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 3.28e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_5211 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 1.06e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_1350 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 1.09e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (22%) - phoR2 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 1.63e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - asgD (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 4.59e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_7059 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 2.20e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_5314 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 2.69e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_4165 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 1.53e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_3451 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 6.00e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1592 (25%) - sll0649 (3%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 7.84e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_6149 (22%) - MXAN_7396 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 1.63e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (22%) - phoP2 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 3.40e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

zraR (11%) - zraS (6%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 4.44e-12

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

fruA (17%) - MXAN_7396 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 2.00e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_3450 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 4.16e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (22%) - MXAN_5853 (3%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 1.25e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_4245 (3%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 1.17e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (4)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID	predicted interaction	Response_reg	GerE
structural domain contact	3DID	predicted interaction	Response_reg	HisKA
structural domain contact	3DID	predicted interaction	Response_reg	PAS

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