The Microbial Protein Interaction Database

physical association

MXAN_2606 (88%) - phoR3 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 32% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_2606 (88%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 29% Positives: 34% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_2606 (88%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 29% Positives: 35% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (88%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 29% Positives: 35% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_2606 (88%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 33% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_2606 (88%) - MXAN_1166 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 34% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_2606 (88%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 34% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_2606 (88%) - MXAN_1350 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 33% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_2606 (88%) - MXAN_2785 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 35% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_2606 (88%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 32% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (88%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 31% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_2606 (88%) - phoR2 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 32% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_2606 (88%) - MXAN_7363 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 34% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (88%) - MXAN_3606 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 33% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_2606 (88%) - MXAN_7142 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 27% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (7%) - MXAN_3451 (76%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 27% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_1350 (7%) - MXAN_3451 (76%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 28% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - MXAN_3451 (76%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 29% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_3451 (76%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 23% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - MXAN_3451 (76%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 22% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (4%) - MXAN_3451 (76%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 20% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (4%) - MXAN_3451 (76%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 23% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (4%) - MXAN_3451 (76%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 21% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (13%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 1.02e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (13%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 5.08e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - MXAN_5314 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 14% E-Value: 8.69e-14

Method

DB Source

Type

Publication

physical association

pilS (7%) - MXAN_5314 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 14% E-Value: 7.11e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (13%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 5.44e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (13%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 1.81e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (13%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 1.64e-20

Method

DB Source

Type

Publication

physical association

MXAN_2785 (9%) - MXAN_2785 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 2.98e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (13%) - MXAN_7363 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 1.87e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (9%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 1.03e-14

Method

DB Source

Type

Publication

physical association

MXAN_7363 (9%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 9.29e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (9%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 2.89e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (9%) - MXAN_2785 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.69e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1400 (9%) - sll0474 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 1.94e-13

Method

DB Source

Type

Publication

physical association

sll1228 (9%) - sll1229 (7%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 3.09e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_7396 (4%) - MXAN_5314 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 4.31e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 4.04e-11

Method

DB Source

Type

Publication

physical association

MXAN_7206 (7%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 2.53e-13

Method

DB Source

Type

Publication

physical association

pilS (7%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 3.30e-13

Method

DB Source

Type

Publication

physical association

pilS (7%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 2.07e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 6.03e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (9%) - pilS (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 4.93e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (4%) - MXAN_5314 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 5.63e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (7%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 1.69e-13

Method

DB Source

Type

Publication

physical association

MXAN_1350 (7%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 1.06e-15

Method

DB Source

Type

Publication

physical association

MXAN_1350 (7%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 2.53e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (7%) - MXAN_1350 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 8.69e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - phoR3 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 2.37e-11

Method

DB Source

Type

Publication

physical association

pilS (7%) - phoR3 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 1.94e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (4%) - MXAN_5314 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 10% E-Value: 1.26e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 1.26e-12

Method

DB Source

Type

Publication

physical association

MXAN_1350 (7%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 5.27e-15

Method

DB Source

Type

Publication

physical association

MXAN_7206 (7%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 6.44e-13

Method

DB Source

Type

Publication

physical association

pilS (7%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 5.27e-15

Method

DB Source

Type

Publication

physical association

MXAN_1350 (7%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 2.70e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1166 (7%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 2.62e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1166 (7%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 1.64e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - MXAN_1166 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 1.48e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_5314 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 11% E-Value: 9.61e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - MXAN_2785 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 7.36e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (9%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.58e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4246 (6%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 8.41e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cpxR (5%) - cpxA (8%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 1.69e-13

Method	DB Source	Type	Publication
unspecified method		physical association	Nakayama S et al. (2003)

slr1147 (5%) - sll1124 (9%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 2.14e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

prrA (5%) - prrB (10%) (Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 4.17e-16

Method	DB Source	Type	Publication
enzymatic study		direct interaction	Nowak E et al. (2006)

rstA (6%) - rstB (10%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 1.06e-11

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

pleD (5%) - pleC (9%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 4.46e-14

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

pleD (5%) - divJ (11%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 3.19e-16

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

MXAN_5995 (5%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 9.61e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 5.10e-14

Method

DB Source

Type

Publication

physical association

MXAN_7206 (7%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 4.46e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (7%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 1.10e-12

Method

DB Source

Type

Publication

physical association

MXAN_7398 (5%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 2.29e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (7%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 5.63e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - phoR2 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 1.94e-09

Method

DB Source

Type

Publication

physical association

pilS (7%) - phoR2 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 1.59e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (7%) - phoR2 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 8.14e-12

Method

DB Source

Type

Publication

physical association

MXAN_7398 (5%) - phoR3 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 9% E-Value: 9.00e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - phoR3 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 9% E-Value: 1.17e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 9% E-Value: 3.42e-10

Method

DB Source

Type

Publication

physical association

phoP2 (5%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 9% E-Value: 2.14e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 9% E-Value: 5.10e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - phoR3 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 9% E-Value: 2.00e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (5%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 4.77e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP3 (5%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 9% E-Value: 2.45e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 1.06e-11

Method

DB Source

Type

Publication

physical association

MXAN_7398 (5%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 2.45e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 1.30e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 1.53e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 5.45e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1166 (7%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 2.89e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1166 (7%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 4.46e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (5%) - MXAN_1166 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 5.64e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (4%) - phoR3 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 9% E-Value: 9.62e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (5%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 1.30e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (5%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 4.03e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - MXAN_2785 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 1.75e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - MXAN_7363 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 4.61e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (5%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 9% E-Value: 2.14e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (5%) - phoR3 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 9% E-Value: 8.41e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (5%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 4.46e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (5%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 2.29e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - MXAN_7142 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 1.30e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (7%) - MXAN_7142 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 9% E-Value: 5.45e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (6%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 1.94e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (6%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 3.53e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (7%) - MXAN_0459 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 8.70e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (8%) - MXAN_0459 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 2.45e-08

Method

DB Source

Type

Publication

physical association

basR (4%) - basS (9%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 3.78e-09

Method	DB Source	Type	Publication
coimmunoprecipitation		physical association	Kato A et al. (2004)

sll0474 (5%) - slr1400 (7%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 4.61e-11

Method

DB Source

Type

Publication

physical association

sll0797 (4%) - sll0798 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 9.00e-11

Method

DB Source

Type

Publication

physical association

slr1909 (4%) - sll1003 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 9.61e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1124 (6%) - slr1147 (7%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 5.45e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1783 (4%) - slr1147 (7%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.99e-10

Method

DB Source

Type

Publication

physical association

sll0790 (8%) - sll0790 (5%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.81e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll0789 (4%) - sll0790 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 4.61e-11

Method

DB Source

Type

Publication

physical association

slr1909 (4%) - slr0210 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 4.93e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1037 (4%) - slr1393 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.59e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll0649 (5%) - slr0533 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.10e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

yycF (5%) - yycG (9%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.75e-14

Method	DB Source	Type	Publication
enzymatic study		physical association	Fukuchi K et al. (2000)

kinA (7%) - kinA (6%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 8.42e-09

Method	DB Source	Type	Publication
blue native page		physical association	Eswaramoorthy P et al. (2009)
coimmunoprecipitation		physical association	Eswaramoorthy P et al. (2009)
cross-linking study		physical association	Eswaramoorthy P et al. (2009)

A2VGV6 (4%) - kdpD (9%) (Mycobacterium tuberculosis C - Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.43e-12

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Davey CA et al. (2002)

yedW (5%) - yedV (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.45e-12

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

zraR (4%) - zraS (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 4.18e-08

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

kdpE (5%) - kdpD (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.06e-11

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Luttmann D et al. (2009)
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)
enzymatic study		physical association	Heermann R et al. (2003)
protein kinase assay		physical association	Luttmann D et al. (2009)

torR (4%) - torS (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.00e-10

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

ompR (5%) - envZ (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 9.30e-12

Method	DB Source	Type	Publication
electrophoretic mobility shift assay		physical association	Harlocker SL et al. (1995)
far western blotting		physical association	Cai SJ et al. (2002)
pull down		physical association	Cai SJ et al. (2002)

divK (3%) - pleC (9%) (Brucella abortus - Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.64e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Hallez R et al. (2007)

divK (4%) - pleC (9%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 8.42e-09

Method

DB Source

Type

Publication

dephosphorylation

phosphorylation

divK (4%) - divJ (11%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 6.03e-11

Method

DB Source

Type

Publication

protein kinase assay

phosphorylation

Paul R et al. (2008)

MXAN_7143 (4%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 3.10e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.71e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 5.46e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.06e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 4.94e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 8.14e-12

Method

DB Source

Type

Publication

physical association

MXAN_5211 (4%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 4.94e-09

Method

DB Source

Type

Publication

physical association

asgD (4%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 3.09e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 6.66e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.22e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 2.00e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.26e-12

Method

DB Source

Type

Publication

physical association

phoP3 (5%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.62e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

nla28 (4%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.48e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.99e-10

Method

DB Source

Type

Publication

physical association

asgD (4%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 7.37e-09

Method

DB Source

Type

Publication

physical association

MXAN_5211 (4%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 7.37e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (4%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.62e-10

Method

DB Source

Type

Publication

physical association

MXAN_3450 (4%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.64e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (4%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 3.91e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (5%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.70e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.39e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (4%) - MXAN_1350 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 1.30e-09

Method

DB Source

Type

Publication

physical association

MXAN_0460 (4%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.07e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (5%) - phoR2 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 7.37e-09

Method

DB Source

Type

Publication

physical association

MXAN_7396 (4%) - phoR2 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 9.62e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - phoR2 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.37e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - phoR2 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 3.91e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (4%) - phoR2 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.26e-08

Method

DB Source

Type

Publication

physical association

MXAN_7143 (4%) - phoR3 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 5.46e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - phoR3 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.89e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.14e-09

Method

DB Source

Type

Publication

physical association

phoP2 (5%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 3.78e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 5.83e-10

Method

DB Source

Type

Publication

physical association

phoP2 (5%) - phoR2 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.64e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (4%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 3.20e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (4%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.00e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (4%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 4.78e-08

Method

DB Source

Type

Publication

physical association

pilR (4%) - MXAN_1350 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 8.42e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (4%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 2.61e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (4%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 6.23e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (4%) - MXAN_1350 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.10e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (4%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 5.83e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (4%) - MXAN_1350 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 1.53e-10

Method

DB Source

Type

Publication

physical association

phoR1 (4%) - phoR2 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 2.80e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (4%) - phoR3 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 3.42e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 6.23e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (4%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.89e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (9%) - phoR1 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.81e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (4%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 8.14e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (4%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.03e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 3.20e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (4%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.48e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 7.87e-11

Method

DB Source

Type

Publication

physical association

MXAN_5211 (4%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 7.87e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (4%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 9.30e-12

Method

DB Source

Type

Publication

physical association

MXAN_6688 (5%) - MXAN_1166 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 2.99e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (4%) - MXAN_1166 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 1.81e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (4%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 1.81e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (4%) - pilS (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.45e-08

Method

DB Source

Type

Publication

physical association

MXAN_3451 (4%) - MXAN_1350 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 4.32e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (4%) - phoR2 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 7.88e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (4%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 5.10e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (4%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 2.62e-10

Method

DB Source

Type

Publication

physical association

MXAN_4645 (4%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.48e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 4.46e-10

Method

DB Source

Type

Publication

physical association

MXAN_4645 (4%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.80e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 7.61e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_1350 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.17e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (5%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.43e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5889 (4%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 4.18e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5889 (4%) - phoR3 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.22e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_2785 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 3.65e-12

Method

DB Source

Type

Publication

physical association

asgD (4%) - MXAN_2785 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 9.00e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_2785 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.48e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (4%) - MXAN_2785 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 9.00e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (4%) - MXAN_2785 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.06e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_2785 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 8.14e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (4%) - MXAN_2785 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 4.77e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_3606 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 4.04e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (5%) - MXAN_7363 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.75e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_7363 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 9.30e-12

Method

DB Source

Type

Publication

physical association

phoR1 (4%) - MXAN_7363 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 6.66e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.06e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 9.61e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 6.02e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.64e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_2785 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.75e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (5%) - MXAN_7363 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.64e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (4%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 1.10e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (4%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 9.95e-10

Method

DB Source

Type

Publication

physical association

fluorescent resonance energy transfer

MXAN_5853 (4%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 6.23e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (4%) - sdeK (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 1.59e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (5%) - MXAN_0459 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 3.31e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - MXAN_0459 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 2.07e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (4%) - MXAN_0459 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 8% E-Value: 1.26e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0461 (4%) - MXAN_5211 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 9% E-Value: 5.10e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP1 (4%) - phoR1 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 6% Positives: 10% E-Value: 3.77e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

divK (3%) - BruAb1_0598 (8%) (Brucella abortus)

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 3.54e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Hallez R et al. (2007)

phoP (4%) - phoQ (6%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 8.15e-08

Method	DB Source	Type	Publication
far western blotting		physical association	Chamnongpol S et al. (2000)
surface plasmon resonance		physical association	Castelli ME et al. (2003)

sasA (8%) - sasA (4%) (Synechococcus sp (strain PCC 7942) (Anacystis nidulans R2))

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 6.66e-10

Method	DB Source	Type	Publication
pull down		physical association	Iwasaki H et al. (2000)

cph1 (7%) - cph1 (3%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 4.78e-08

Method

DB Source

Type

Publication

direct interaction

Otto H et al. (2003)

protein kinase assay

phosphorylation

Yeh KC et al. (1997)

sll0797 (4%) - slr1147 (7%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 1.44e-08

Method

DB Source

Type

Publication

physical association

slr1594 (3%) - sasA (9%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 1.03e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1584 (4%) - sll1475 (7%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 1.53e-10

Method

DB Source

Type

Publication

physical association

sll1624 (3%) - slr0210 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 6.45e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1291 (3%) - sasA (9%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 6.89e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1584 (4%) - CcaS (7%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 1.53e-10

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation reaction	Hirose Y et al. (2008)

spo0F (4%) - kinA (7%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 4.04e-07

Method	DB Source	Type	Publication
genetic interference		physical association	Stephenson SJ et al. (2002)

cheY (3%) - arcB (8%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 1.59e-07

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

basR (4%) - basS (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 3.91e-10

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

creB (4%) - creC (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 3.78e-09

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

kdpD (8%) - kdpD (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 1.26e-08

Method	DB Source	Type	Publication
experimental interaction detection		physical association	Ballal A et al. (2002)

phoP (4%) - phoQ (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 4.18e-08

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

MXAN_5211 (4%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 1.64e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (4%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 7% E-Value: 5.46e-08

Method

DB Source

Type

Publication

physical association

MXAN_0460 (4%) - MXAN_6688 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 3.66e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (4%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 5.64e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (4%) - MXAN_1350 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 8.70e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (4%) - asgD (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 1.06e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (4%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 9.95e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5889 (4%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 6.45e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5212 (4%) - MXAN_3606 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 3.66e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (4%) - MXAN_7398 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 1.70e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_7142 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 2.62e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (4%) - MXAN_0459 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 9% E-Value: 2.14e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (4%) - MXAN_0459 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 5% Positives: 8% E-Value: 7.13e-08

Method

DB Source

Type

Publication

physical association