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The Microbial Protein Interaction Database

Interaction Evidences

MXAN_1680 - MXAN_4164 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1DBP1 DNA-binding response regulator MXAN_1680	Q1D4T4 DNA-binding response regulator MXAN_4164
CMR Search...	CMR Search...
GO MF: DNA binding GO MF: two-component response regulator activity GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: DNA binding GO MF: two-component response regulator activity GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (134)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (130)

MXAN_1680 (91%) - MXAN_3450 (29%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 51% Positives: 63% E-Value: 5.76e-66

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (88%) - MXAN_4164 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 50% Positives: 63% E-Value: 8.89e-63

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (17%) - MXAN_4164 (88%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 38% Positives: 51% E-Value: 1.16e-62

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (14%) - MXAN_4164 (88%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 42% E-Value: 6.37e-61

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (91%) - pilR (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 34% Positives: 45% E-Value: 9.20e-60

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoB (36%) - phoB (29%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 32% Positives: 51% E-Value: 1.94e-25

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

baeR (38%) - baeR (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 32% Positives: 49% E-Value: 9.93e-26

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpE (28%) - creB (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 31% Positives: 48% E-Value: 8.99e-23

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_3450 (29%) - MXAN_3450 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 46% E-Value: 4.47e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (33%) - MXAN_5212 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 46% E-Value: 4.47e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (29%) - phoP2 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 48% E-Value: 2.53e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cpxR (31%) - cpxR (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 30% Positives: 46% E-Value: 5.28e-19

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (29%) - ompR (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 30% Positives: 48% E-Value: 1.14e-21

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

qseB (28%) - qseB (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 30% Positives: 46% E-Value: 5.64e-21

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_3450 (33%) - MXAN_1680 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 45% E-Value: 3.54e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (25%) - MXAN_5313 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 46% E-Value: 4.17e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP (30%) - phoP (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 29% Positives: 47% E-Value: 1.49e-17

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)
molecular sieving		physical association	Bachhawat P et al. (2007)
x-ray crystallography		physical association	Bachhawat P et al. (2007)

yedW (27%) - cusR (30%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 29% Positives: 46% E-Value: 1.03e-18

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoP2 (33%) - phoP2 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 29% Positives: 45% E-Value: 3.42e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

yedW (28%) - yedW (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 28% Positives: 47% E-Value: 3.20e-20

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpE (28%) - rstA (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 28% Positives: 44% E-Value: 2.08e-15

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (27%) - yedW (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 28% Positives: 47% E-Value: 3.42e-18

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (30%) - cusR (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 28% Positives: 46% E-Value: 1.10e-16

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_5212 (27%) - MXAN_3450 (29%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 43% E-Value: 1.59e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0797 (25%) - sll0797 (30%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 27% Positives: 46% E-Value: 5.65e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

phoP (36%) - phoP (21%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 27% Positives: 42% E-Value: 6.44e-25

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

ompR (18%) - phoB (36%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 26% Positives: 41% E-Value: 1.59e-23

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

asgD (18%) - phoP3 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 37% E-Value: 1.88e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

ompR (31%) - ompR (18%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 24% Positives: 39% E-Value: 9.31e-20

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

creB (33%) - creB (18%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 24% Positives: 37% E-Value: 5.10e-22

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

creB (18%) - kdpE (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 24% Positives: 35% E-Value: 3.20e-16

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_3450 (33%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 36% E-Value: 9.32e-16

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (18%) - phoP2 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 36% E-Value: 1.88e-16

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (17%) - MXAN_1349 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 38% E-Value: 2.37e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1592 (15%) - sll0649 (34%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 23% Positives: 36% E-Value: 4.04e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_5995 (30%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 35% E-Value: 7.63e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (33%) - MXAN_7396 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 34% E-Value: 6.90e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_6149 (17%) - phoP2 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 36% E-Value: 4.18e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (17%) - phoP2 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 38% E-Value: 1.34e-18

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4072 (16%) - phoP2 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 33% E-Value: 4.62e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

arcA (30%) - arcA (16%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 22% Positives: 35% E-Value: 4.32e-17

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2606 (17%) - MXAN_5995 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 3.20e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP3 (28%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 34% E-Value: 9.98e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (17%) - MXAN_3450 (29%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 3.66e-16

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7143 (14%) - phoP2 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 34% E-Value: 6.90e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (30%) - MXAN_4645 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 33% E-Value: 7.63e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (33%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 32% E-Value: 4.19e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (28%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 35% E-Value: 5.84e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0649 (32%) - sll1592 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 7.90e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

rstA (14%) - kdpE (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 1.54e-14

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoP2 (25%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 1.82e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (25%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 1.94e-13

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (14%) - phoP2 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 31% E-Value: 7.37e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (30%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 31% E-Value: 3.43e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5212 (27%) - MXAN_7396 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 32% E-Value: 2.45e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (28%) - MXAN_7396 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 33% E-Value: 4.33e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (28%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 31% E-Value: 2.63e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (29%) - MXAN_4645 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 1.44e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (29%) - MXAN_7363 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 32% E-Value: 7.63e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (12%) - MXAN_5313 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 9.62e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (33%) - MXAN_6296 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 32% E-Value: 2.15e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

rstA (28%) - rstA (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 20% Positives: 33% E-Value: 5.65e-13

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_7396 (14%) - MXAN_3450 (29%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 29% E-Value: 2.01e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (25%) - MXAN_7396 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 32% E-Value: 1.44e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (33%) - pilR (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 33% E-Value: 7.14e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (14%) - MXAN_5212 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 30% E-Value: 2.01e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (30%) - MXAN_6296 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 31% E-Value: 1.76e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5212 (27%) - MXAN_7024 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 31% E-Value: 2.38e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1905 (18%) - slr1305 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 1.64e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

torR (26%) - torR (13%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 19% Positives: 34% E-Value: 2.22e-13

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_5995 (30%) - pilR (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 5.85e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (12%) - MXAN_5995 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 33% E-Value: 1.88e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (29%) - pilR (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 32% E-Value: 1.10e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr2098 (17%) - slr2100 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 1.54e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

asgD (18%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 1.07e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (18%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 2.22e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr2104 (14%) - slr1305 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 2.30e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcB (18%) - cheY (15%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 17% Positives: 26% E-Value: 2.30e-10

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

MXAN_2606 (17%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 7.14e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (17%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 7.63e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (18%) - MXAN_7396 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 7.90e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (18%) - cheB1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 5.12e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (17%) - cheB1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 26% E-Value: 3.66e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (18%) - nla28 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 26% E-Value: 4.95e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (17%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 2.22e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (17%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 2.38e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (18%) - MXAN_4645 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 26% E-Value: 1.07e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (16%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 2.63e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1305 (16%) - slr2104 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 3.32e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (16%) - sll1905 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 2.38e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2100 (15%) - slr2098 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 2.38e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcB (18%) - hnr (13%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 1.95e-09

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

MXAN_7143 (14%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 3.67e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (17%) - MXAN_7396 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 5.65e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (17%) - MXAN_7396 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 1.76e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (17%) - MXAN_4645 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 7.63e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (18%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 4.79e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (16%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 22% E-Value: 1.18e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (17%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 3.43e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (17%) - MXAN_7363 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 4.05e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (18%) - MXAN_6296 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 2.46e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

bvgS (18%) - bvgA (12%) (Bordetella pertussis)

Geometric mean of BLAST Identity: 15% Positives: 20% E-Value: 2.01e-06

Method	DB Source	Type	Publication
genetic interference		physical association	Merkel TJ et al. (2003)

slr1759 (15%) - slr1594 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 1.30e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (15%) - slr1760 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 6.91e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

glnG (14%) - glnG (15%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 4.48e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Salinas P et al. (2003)

MXAN_7396 (14%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 3.92e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (14%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 4.19e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (14%) - cheB1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 2.01e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (17%) - frzS (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 3.54e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (18%) - pilR (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 8.17e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (12%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 4.19e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (12%) - MXAN_2606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 4.48e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (14%) - MXAN_4645 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 4.19e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7143 (14%) - MXAN_4645 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 3.92e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (16%) - MXAN_0460 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 1.03e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (17%) - MXAN_6296 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 1.76e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

TP_0519 (14%) - TP_0519 (13%) (Treponema pallidum)

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 3.79e-09

Method

DB Source

Type

Publication

two hybrid array

physical association

Titz B et al. (2008)

hnr (13%) - arcB (16%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 3.11e-07

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

MXAN_0460 (14%) - MXAN_0460 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 2.72e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (17%) - pilR (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 5.85e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (12%) - MXAN_7396 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 3.32e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (14%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 1.88e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4645 (12%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 2.01e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4245 (13%) - MXAN_0460 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 2.30e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (14%) - MXAN_6296 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 9.65e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (14%) - MXAN_6296 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 9.04e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (15%) - MXAN_6296 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 1.59e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1229 (10%) - sll1228 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 4.33e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1760 (14%) - slr1759 (12%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 25% E-Value: 1.59e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_7396 (14%) - pilR (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 3.21e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (3)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Trans_reg_C
structural domain contact	3DID	predicted interaction	Trans_reg_C	Trans_reg_C

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