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The Microbial Protein Interaction Database

Interaction Evidences

MXAN_7396 - MXAN_4645 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1CVS0 Response regulator/adenylate cyclase MXAN_7396	Q1D3G2 Response regulator MXAN_4645
CMR Search...	CMR Search...
GO MF: adenylate cyclase activity GO MF: two-component response regulator activity GO BP: intracellular signaling cascade GO BP: regulation of transcription, DNA-dependent GO BP: cyclic nucleotide biosynthetic process GO BP: two-component signal transduction system (p...	GO MF: two-component response regulator activity GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (113)

Experiments (1)

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

Interologs (111)

MXAN_7396 (94%) - MXAN_2606 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 54% Positives: 65% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (94%) - MXAN_4164 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 54% Positives: 70% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (94%) - phoP2 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 52% Positives: 63% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (94%) - asgD (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 51% Positives: 64% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (94%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 49% Positives: 66% E-Value: 0

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (94%) - MXAN_5212 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 49% Positives: 65% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (94%) - pilR (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 48% Positives: 60% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (94%) - MXAN_3450 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 47% Positives: 62% E-Value: 0

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (94%) - MXAN_6296 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 47% Positives: 57% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (10%) - MXAN_4645 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 37% E-Value: 2.47e-43

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (9%) - MXAN_4645 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 35% E-Value: 2.02e-41

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_4645 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 35% E-Value: 1.19e-41

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5995 (9%) - MXAN_2606 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 23% E-Value: 9.47e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (10%) - MXAN_2606 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 26% E-Value: 1.24e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (10%) - phoP2 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 3.05e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (10%) - phoP2 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 24% E-Value: 2.85e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - frzZ (34%) (Myxococcus xanthus (strain DK 1622) - Myxococcus xanthus)

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 5.55e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

cpxR (33%) - cpxR (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 3.37e-12

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoP3 (9%) - asgD (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 7.50e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (9%) - MXAN_2606 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 1.97e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_6149 (10%) - asgD (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 6.14e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (9%) - MXAN_2606 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 8.57e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_4164 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 2.33e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (10%) - pilR (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 9.47e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (10%) - MXAN_7363 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 1.28e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5212 (9%) - MXAN_7024 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 7.25e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0797 (26%) - sll0797 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.85e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1905 (8%) - slr1305 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 2.75e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (7%) - sll1905 (30%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 1.28e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (8%) - slr1760 (29%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 5.37e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

yedW (25%) - yedW (9%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 2.11e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (31%) - ompR (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 2.66e-13

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

torR (28%) - torR (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 9.17e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (7%) - ompR (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 7.01e-14

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (8%) - phoB (29%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 2.66e-13

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (29%) - phoB (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 7.01e-14

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpE (8%) - creB (29%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 7.75e-13

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoP (21%) - phoP (10%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 1.32e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)
molecular sieving		physical association	Bachhawat P et al. (2007)
x-ray crystallography		physical association	Bachhawat P et al. (2007)

yedW (9%) - cusR (26%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 2.85e-11

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2606 (8%) - asgD (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 2.76e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_5995 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 7.50e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (31%) - MXAN_2606 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 5.55e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (8%) - frzS (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 1.24e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_3450 (9%) - MXAN_7396 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 3.26e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_6149 (10%) - MXAN_7396 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 2.04e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - phoP2 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 1.37e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5995 (9%) - pilR (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 7.76e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (9%) - pilR (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 1.62e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_1349 (29%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 3.37e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (9%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 1.56e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (9%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 3.26e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5212 (9%) - MXAN_7396 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 5.20e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5212 (9%) - MXAN_3450 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 8.58e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (9%) - MXAN_5212 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 2.11e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_7363 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 6.14e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_2606 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 2.58e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (31%) - MXAN_4164 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 1.08e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (7%) - MXAN_4164 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 6.34e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_5313 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 9.16e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1228 (6%) - sll1229 (32%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 3.37e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1760 (9%) - slr1759 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 2.76e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2100 (8%) - slr2098 (24%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 9.47e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2098 (6%) - slr2100 (35%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 6.78e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

phoP (25%) - phoP (8%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 6.13e-14

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

creB (29%) - creB (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 4.54e-13

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

creB (7%) - kdpE (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 1.91e-11

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

glnG (25%) - glnG (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 1.41e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Salinas P et al. (2003)

cusR (7%) - yedW (25%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 2.04e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (26%) - cusR (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 2.76e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2606 (8%) - MXAN_7396 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 9.17e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (9%) - aglZ (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 1.56e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (24%) - MXAN_3450 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 5.37e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_3450 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 1.51e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (7%) - asgD (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 1.24e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_2606 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 2.49e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (28%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 6.14e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - pilR (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 4.55e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (7%) - pilR (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 1.24e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (9%) - MXAN_1680 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 9.47e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (9%) - aglZ (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 6.79e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 9.17e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 4.25e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (9%) - MXAN_6296 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 8.58e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (9%) - MXAN_6296 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 1.79e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1229 (7%) - sll1228 (24%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 4.70e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (7%) - slr2104 (24%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 6.78e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcA (26%) - arcA (7%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 3.15e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

rstA (6%) - kdpE (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 5.20e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpE (8%) - rstA (21%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 1.16e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

qseB (21%) - qseB (8%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 24% E-Value: 1.08e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

baeR (26%) - baeR (6%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 4.40e-12

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2606 (8%) - aglZ (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 4.40e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_3605 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 24% E-Value: 3.37e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (7%) - MXAN_7396 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 4.11e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (7%) - MXAN_3450 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 4.11e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (7%) - MXAN_3605 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 9.17e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (6%) - MXAN_5995 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 2.41e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (6%) - MXAN_2606 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 1.79e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_7396 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 4.25e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_1680 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 1.24e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (6%) - MXAN_5313 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 6.56e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (8%) - MXAN_6296 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 5.03e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7024 (6%) - MXAN_5212 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 1.28e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1759 (8%) - slr1594 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 23% E-Value: 1.28e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

phoP2 (7%) - MXAN_7143 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 4.55e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (6%) - asgD (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 8.87e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (6%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 2.95e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

rstA (21%) - rstA (6%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 1.85e-06

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_4645 (6%) - MXAN_7143 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 3.26e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1594 (6%) - slr1759 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 21% E-Value: 7.26e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1594 (19%) - slr1594 (6%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 21% E-Value: 3.26e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

Domain-Domain Interactions (1)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg

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