The Microbial Protein Interaction Database

physical association

phoR1 (14%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 31% E-Value: 2.97e-30

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (14%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 30% E-Value: 5.61e-29

Method

DB Source

Type

Publication

physical association

MXAN_2606 (13%) - MXAN_1349 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 31% E-Value: 2.44e-28

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (15%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 31% E-Value: 8.65e-30

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 30% E-Value: 1.48e-25

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (13%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 28% E-Value: 7.10e-20

Method

DB Source

Type

Publication

physical association

MXAN_2606 (13%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 30% E-Value: 1.17e-26

Method

DB Source

Type

Publication

physical association

slr0533 (10%) - sll0649 (35%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 19% Positives: 27% E-Value: 3.89e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2098 (18%) - slr2100 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 19% Positives: 27% E-Value: 1.13e-25

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

pilS (12%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 5.82e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 26% E-Value: 2.98e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (12%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 1.10e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (12%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 1.48e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (12%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 29% E-Value: 1.17e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 8.11e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_5313 (82%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 24% E-Value: 5.57e-53

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1905 (17%) - slr1305 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 3.64e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

yycG (10%) - yycF (34%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 7.32e-29

Method	DB Source	Type	Publication
enzymatic study		physical association	Fukuchi K et al. (2000)

MXAN_5211 (11%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 26% E-Value: 5.63e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (9%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 26% E-Value: 1.99e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (9%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 26% E-Value: 4.30e-25

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cpxA (8%) - cpxR (37%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 2.88e-21

Method	DB Source	Type	Publication
unspecified method		physical association	Nakayama S et al. (2003)

CcaS (10%) - slr1584 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 1.43e-20

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation reaction	Hirose Y et al. (2008)

torS (11%) - torR (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 1.87e-16

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

asgD (9%) - phoP3 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 23% E-Value: 2.28e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (9%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 1.58e-19

Method

DB Source

Type

Publication

physical association

MXAN_7398 (9%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 24% E-Value: 1.38e-19

Method

DB Source

Type

Publication

physical association

phoR1 (14%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 24% E-Value: 7.58e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (15%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 9.26e-28

Method

DB Source

Type

Publication

physical association

MXAN_4165 (9%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 2.44e-24

Method

DB Source

Type

Publication

physical association

MXAN_0459 (9%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 24% E-Value: 2.44e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr2104 (13%) - slr1305 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 7.58e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1475 (10%) - slr1584 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 2.14e-20

Method

DB Source

Type

Publication

physical association

sll0790 (9%) - sll0789 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 1.43e-20

Method

DB Source

Type

Publication

physical association

slr1759 (15%) - slr1760 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 2.00e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

envZ (7%) - ompR (36%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 6.64e-22

Method	DB Source	Type	Publication
electrophoretic mobility shift assay		physical association	Harlocker SL et al. (1995)
far western blotting		physical association	Cai SJ et al. (2002)
pull down		physical association	Cai SJ et al. (2002)

divJ (13%) - pleD (20%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 9.27e-24

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

MXAN_2606 (19%) - MXAN_2606 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 1.58e-23

Method

DB Source

Type

Publication

physical association

MXAN_7206 (13%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 22% E-Value: 9.60e-17

Method

DB Source

Type

Publication

physical association

MXAN_5314 (8%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 2.98e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (9%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 4.60e-19

Method

DB Source

Type

Publication

physical association

phoR3 (9%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 3.90e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (13%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 8.97e-19

Method

DB Source

Type

Publication

physical association

phoR1 (14%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 1.63e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (7%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 2.28e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (15%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 1.75e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (15%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 4.44e-26

Method

DB Source

Type

Publication

physical association

MXAN_2785 (15%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 8.10e-28

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (14%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 22% E-Value: 4.16e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (18%) - MXAN_2785 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 5.08e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 22% E-Value: 8.67e-22

Method

DB Source

Type

Publication

physical association

MXAN_5996 (7%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 5.81e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1393 (12%) - slr1037 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 6.42e-25

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

prrB (7%) - prrA (34%) (Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 1.06e-15

Method	DB Source	Type	Publication
enzymatic study		direct interaction	Nowak E et al. (2006)

arcB (14%) - cheY (17%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 6.42e-21

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

kdpD (8%) - kdpE (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 2.89e-17

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Luttmann D et al. (2009)
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)
enzymatic study		physical association	Heermann R et al. (2003)
protein kinase assay		physical association	Luttmann D et al. (2009)

MXAN_2606 (13%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 2.98e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 7.59e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (13%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 4.61e-15

Method

DB Source

Type

Publication

physical association

pilS (12%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 1.48e-13

Method

DB Source

Type

Publication

physical association

MXAN_7206 (13%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 2.07e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (7%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 4.03e-15

Method

DB Source

Type

Publication

physical association

phoR2 (7%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 7.61e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (13%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 20% E-Value: 7.86e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 1.29e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (12%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 1.39e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (14%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 7.09e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (14%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 3.64e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (12%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 1.58e-15

Method

DB Source

Type

Publication

physical association

MXAN_3451 (7%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 4.31e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (13%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 8.40e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 1.38e-23

Method

DB Source

Type

Publication

physical association

MXAN_7206 (13%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 20% E-Value: 5.27e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (9%) - MXAN_5212 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 8.40e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - frzZ (15%) (Myxococcus xanthus (strain DK 1622) - Myxococcus xanthus)

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 5.44e-20

Method

DB Source

Type

Publication

physical association

basS (7%) - basR (29%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 8.99e-15

Method	DB Source	Type	Publication
coimmunoprecipitation		physical association	Kato A et al. (2004)

sll0474 (10%) - slr1400 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 3.08e-23

Method

DB Source

Type

Publication

physical association

sll1228 (12%) - sll1229 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 2.28e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

phoP (37%) - phoP (5%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 14% Positives: 19% E-Value: 1.53e-22

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

kdpD (8%) - A2VGV6 (27%) (Mycobacterium tuberculosis C - Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 3.19e-16

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Davey CA et al. (2002)

arcB (14%) - hnr (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 1.21e-19

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

yedV (6%) - yedW (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 4.17e-16

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

basS (7%) - basR (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 2.07e-15

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

rstB (7%) - rstA (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 8.40e-17

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

divJ (13%) - divK (15%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 6.01e-19

Method

DB Source

Type

Publication

protein kinase assay

phosphorylation

Paul R et al. (2008)

pleC (9%) - pleD (20%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 5.62e-25

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

MXAN_5211 (11%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 19% E-Value: 1.43e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 7.61e-14

Method

DB Source

Type

Publication

physical association

MXAN_2606 (13%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 6.22e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (13%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 19% E-Value: 3.78e-13

Method

DB Source

Type

Publication

physical association

pilS (12%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 2.80e-12

Method

DB Source

Type

Publication

physical association

pilS (12%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 7.12e-12

Method

DB Source

Type

Publication

physical association

MXAN_1350 (10%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 2.36e-23

Method

DB Source

Type

Publication

physical association

MXAN_5211 (11%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 19% E-Value: 1.64e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (12%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 1.21e-11

Method

DB Source

Type

Publication

physical association

MXAN_5211 (11%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 7.11e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (10%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 2.21e-25

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (12%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 1.48e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (12%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 2.99e-14

Method

DB Source

Type

Publication

physical association

sdeK (12%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 7.61e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 6.66e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (13%) - MXAN_5889 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 4.93e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 19% E-Value: 4.17e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (35%) - MXAN_4164 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 1.69e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5996 (7%) - MXAN_5212 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 1.14e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (13%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 4.76e-20

Method

DB Source

Type

Publication

physical association

MXAN_7142 (10%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 6.03e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1003 (8%) - slr1909 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 4.17e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (15%) - slr1594 (11%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 25% E-Value: 6.42e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1353 (9%) - sll1905 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 4.45e-18

Method

DB Source

Type

Publication

physical association

slr0210 (8%) - slr1909 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 1.21e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

cpxR (36%) - cpxR (5%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 1.53e-18

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (5%) - ompR (36%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 1.93e-21

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (35%) - phoB (5%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 1.87e-20

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

creC (6%) - creB (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 8.99e-15

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

glnL (9%) - glnG (19%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 7.12e-12

Method

DB Source

Type

Publication

physical association

Salinas P et al. (2003)

MXAN_7059 (9%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 4.03e-15

Method

DB Source

Type

Publication

physical association

asgD (9%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 6.22e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 3.65e-12

Method

DB Source

Type

Publication

physical association

asgD (9%) - nla28 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 3.09e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5314 (8%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 18% E-Value: 7.61e-14

Method

DB Source

Type

Publication

physical association

MXAN_1350 (10%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 18% E-Value: 9.28e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (10%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 5.08e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (9%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 5.27e-15

Method

DB Source

Type

Publication

physical association

MXAN_5211 (11%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 6.23e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (10%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 1.93e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (9%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 3.77e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (10%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 2.06e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (9%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 18% E-Value: 2.21e-13

Method

DB Source

Type

Publication

physical association

asgD (9%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 17% E-Value: 3.41e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (13%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 2.89e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (12%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 4.77e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoQ (6%) - phoP (25%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 12% Positives: 23% E-Value: 2.71e-11

Method	DB Source	Type	Publication
far western blotting		physical association	Chamnongpol S et al. (2000)
surface plasmon resonance		physical association	Castelli ME et al. (2003)

sll1592 (4%) - sll0649 (35%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 2.14e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

kinA (9%) - spo0F (16%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 3.78e-13

Method	DB Source	Type	Publication
genetic interference		physical association	Stephenson SJ et al. (2002)

zraS (9%) - zraR (17%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 1.34e-14

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

phoQ (6%) - phoP (25%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 23% E-Value: 6.03e-11

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

pleC (9%) - divK (15%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 3.64e-20

Method

DB Source

Type

Publication

dephosphorylation

phosphorylation

asgD (9%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 5.82e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (9%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 7.61e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (9%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 1.94e-13

Method

DB Source

Type

Publication

physical association

asgD (9%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 2.99e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5314 (8%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 3.65e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 2.07e-15

Method

DB Source

Type

Publication

physical association

MXAN_7398 (9%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 7.36e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (9%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 4.03e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (7%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 1.03e-10

Method

DB Source

Type

Publication

physical association

phoR3 (9%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 4.93e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (9%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 9.93e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (9%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 2.53e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 3.90e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (9%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 5.10e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1166 (8%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 2.89e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (7%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 5.82e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 2.21e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (9%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.64e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (9%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 5.44e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5314 (8%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 6.66e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (9%) - MXAN_5889 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 9.61e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (9%) - MXAN_5889 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 2.71e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 5.62e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5996 (7%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 1.03e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5996 (7%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 5.45e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5996 (7%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 5.10e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5996 (7%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 2.99e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 2.29e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (9%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 5.63e-13

Method

DB Source

Type

Publication

physical association

sll0798 (7%) - sll0797 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 3.65e-16

Method

DB Source

Type

Publication

physical association

sll1229 (8%) - sll1228 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 3.42e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1805 (8%) - sll1708 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.00e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

yedW (31%) - yedW (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 3.09e-15

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpE (4%) - creB (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 6.66e-14

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpE (4%) - rstA (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 7.61e-14

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (4%) - yedW (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 1.17e-14

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

asgD (9%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 2.45e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (7%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 1.94e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (7%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 4.94e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (4%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 3.30e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (7%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 4.77e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_5212 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 1.10e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3606 (4%) - MXAN_5212 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 7.36e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5996 (7%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.62e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (9%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 5.63e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (9%) - MXAN_4245 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 2.99e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (9%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 7.87e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1147 (6%) - sll0797 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 1.87e-12

Method

DB Source

Type

Publication

physical association

slr1147 (6%) - slr1783 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 9.00e-11

Method

DB Source

Type

Publication

physical association

sasA (7%) - sll1291 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 4.17e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1414 (8%) - sll1592 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 7.37e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

phoP (25%) - phoP (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 4.46e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)
molecular sieving		physical association	Bachhawat P et al. (2007)
x-ray crystallography		physical association	Bachhawat P et al. (2007)

cusR (26%) - cusR (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 9.61e-13

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

yedW (4%) - cusR (26%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 2.53e-13

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_5995 (5%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 14% E-Value: 1.26e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (17%) - MXAN_0460 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 1.17e-10

Method

DB Source

Type

Publication

physical association

MXAN_1349 (5%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 2.89e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 13% E-Value: 6.89e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 1.59e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 14% E-Value: 7.62e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 1.48e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 14% E-Value: 8.70e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7024 (4%) - MXAN_5212 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 6.23e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5996 (7%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 1.64e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

bvgA (5%) - bvgS (18%) (Bordetella pertussis)

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 5.64e-09

Method	DB Source	Type	Publication
genetic interference		physical association	Merkel TJ et al. (2003)

sphS (8%) - slr1594 (11%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 18% E-Value: 3.42e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sasA (7%) - slr1594 (11%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 17% E-Value: 7.87e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (4%) - sll1905 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 8.14e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll0649 (5%) - sll1592 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 8.42e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_7396 (4%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 9.95e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 5.27e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (4%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 2.89e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (4%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.53e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (4%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 7.37e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (4%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 4.46e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (6%) - frzZ (15%) (Myxococcus xanthus - Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 17% E-Value: 1.88e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 1.03e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 4.46e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 2.37e-11

Method

DB Source

Type

Publication

physical association

MXAN_7396 (4%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 4.61e-11

Method

DB Source

Type

Publication

physical association

MXAN_5995 (5%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.10e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 2.89e-09

Method

DB Source

Type

Publication

physical association

MXAN_4645 (4%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 1.30e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3606 (4%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 3.53e-11

Method

DB Source

Type

Publication

physical association

MXAN_0460 (6%) - MXAN_4245 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 6.24e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

HP_0392 (4%) - cheY (16%) (Helicobacter pylori (Campylobacter pylori))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 3.42e-10

Method

DB Source

Type

Publication

physical association

Rain JC et al. (2001)

slr1305 (4%) - slr2104 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 2.22e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1760 (4%) - slr1759 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 6.45e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcA (15%) - arcA (5%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 1.06e-11

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

hnr (4%) - arcB (16%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 8.15e-08

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

MXAN_7396 (4%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 2.07e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (4%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 8.42e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (4%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 2.14e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 4.32e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 2.22e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 1.14e-09

Method

DB Source

Type

Publication

physical association