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The Microbial Protein Interaction Database

Interaction Evidences

MXAN_6688 - frzS ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1CXR8 Cyclic nucleotide binding/ATPase domain protein MXAN_6688	Q1D4U9 Response regulator FrzS frzS MXAN_4149
CMR Search...	CMR Search...
GO MF: two-component sensor activity GO MF: ATP binding GO BP: signal transduction GO BP: peptidyl-histidine phosphorylation	GO MF: two-component response regulator activity GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (53)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (52)

MXAN_1350 (11%) - frzS (79%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 38% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - frzS (79%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 29% Positives: 36% E-Value: 0

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_6688 (95%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 34% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (95%) - MXAN_5995 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 33% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (95%) - aglZ (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 35% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (95%) - MXAN_5889 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 32% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (95%) - MXAN_4164 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 33% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (95%) - MXAN_1349 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 33% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (16%) - aglZ (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 1.11e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (16%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 3.35e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoR3 (13%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 5.18e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (16%) - MXAN_4645 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 2.74e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (16%) - MXAN_5889 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 5.34e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (16%) - MXAN_4164 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 3.58e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (13%) - MXAN_5313 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 3.03e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pleC (9%) - pleD (9%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 2.17e-09

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

divJ (9%) - pleD (9%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 4.23e-09

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

MXAN_2606 (10%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.04e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1350 (11%) - MXAN_4645 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 8.82e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (13%) - MXAN_5889 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 8.25e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

torS (9%) - torR (6%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 1.78e-07

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

MXAN_2606 (10%) - MXAN_5995 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 2.40e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - aglZ (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 3.46e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (8%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 6.76e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sdeK (9%) - MXAN_5995 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 1.19e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (9%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 5.18e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (8%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 1.01e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - MXAN_4645 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 8.52e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (10%) - MXAN_1349 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 7.98e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_5995 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 3.03e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (10%) - MXAN_4164 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 4.68e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - MXAN_4164 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.11e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (9%) - MXAN_5313 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 3.03e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (10%) - MXAN_5995 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 5.17e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

BruAb1_0598 (8%) - divK (5%) (Brucella abortus)

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 1.32e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Hallez R et al. (2007)

sll1228 (8%) - sll1229 (5%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 2.94e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1475 (6%) - slr1584 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 4.53e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

CcaS (6%) - slr1584 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 4.53e-07

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation reaction	Hirose Y et al. (2008)

pleC (9%) - divK (5%) (Brucella abortus - Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 3.96e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Hallez R et al. (2007)

pleC (9%) - divK (6%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 9.13e-08

Method

DB Source

Type

Publication

dephosphorylation

phosphorylation

divJ (9%) - divK (6%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 1.78e-07

Method

DB Source

Type

Publication

protein kinase assay

phosphorylation

Paul R et al. (2008)

MXAN_5211 (7%) - aglZ (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 5.72e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (8%) - phoP3 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 6.76e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (7%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 1.36e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (7%) - phoP2 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 11% E-Value: 1.72e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (8%) - MXAN_4645 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 12% E-Value: 5.53e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (7%) - MXAN_4645 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 1.41e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_4645 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 1.08e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (7%) - MXAN_4164 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 10% E-Value: 1.84e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_4164 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 1.41e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (7%) - MXAN_5313 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 7.99e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sasA (7%) - sll1291 (5%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 6% Positives: 11% E-Value: 3.47e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

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