About
Search
Interaction Evidences
Help
Contact Us

The Microbial Protein Interaction Database

Interaction Evidences

MXAN_3450 - MXAN_6296 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1D6S6 DNA-binding heavy metal response regulator MXAN_3450	Q1CYV2 Response regulator MXAN_6296
CMR Search...	CMR Search...
GO MF: DNA binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: two-component response regulator activity GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (41)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (38)

MXAN_5995 (31%) - MXAN_6296 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 55% Positives: 65% E-Value: 6.19e-46

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (88%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 46% Positives: 59% E-Value: 7.05e-58

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_0460 (15%) - MXAN_6296 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 39% Positives: 47% E-Value: 5.07e-40

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (14%) - MXAN_6296 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 37% Positives: 48% E-Value: 7.57e-40

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (13%) - MXAN_6296 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 36% Positives: 43% E-Value: 3.07e-41

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP (28%) - phoP (32%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 30% Positives: 48% E-Value: 1.44e-18

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

MXAN_1680 (33%) - MXAN_4164 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 45% E-Value: 6.68e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cpxR (27%) - cpxR (29%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 28% Positives: 45% E-Value: 5.11e-12

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoP2 (31%) - MXAN_7143 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 44% E-Value: 4.78e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (28%) - MXAN_4164 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 43% E-Value: 5.84e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (34%) - MXAN_4645 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 41% E-Value: 2.90e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoB (25%) - phoB (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 27% Positives: 43% E-Value: 1.54e-12

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

creB (29%) - kdpE (25%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 27% Positives: 39% E-Value: 2.90e-11

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

baeR (25%) - baeR (29%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 27% Positives: 45% E-Value: 1.70e-11

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_5995 (31%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 40% E-Value: 3.00e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (31%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 41% E-Value: 4.18e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5995 (31%) - MXAN_4645 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 38% E-Value: 4.47e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

ompR (26%) - phoB (25%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 26% Positives: 44% E-Value: 1.70e-11

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

rstA (27%) - kdpE (25%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 26% Positives: 39% E-Value: 8.72e-12

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_4164 (28%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 40% E-Value: 7.38e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (27%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 41% E-Value: 5.29e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

arcA (23%) - arcA (23%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 23% Positives: 41% E-Value: 5.12e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2606 (14%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 33% E-Value: 2.90e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (14%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 33% E-Value: 5.85e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (13%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 31% E-Value: 3.79e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (14%) - MXAN_4164 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 32% E-Value: 5.85e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr2104 (13%) - slr1305 (26%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 7.39e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

glnG (27%) - glnG (13%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 19% Positives: 27% E-Value: 1.14e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Salinas P et al. (2003)

MXAN_7396 (13%) - MXAN_4164 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 1.18e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (14%) - MXAN_4164 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 32% E-Value: 2.90e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (24%) - MXAN_2606 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 3.67e-06

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (13%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 1.49e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (13%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 4.79e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (13%) - MXAN_4645 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 25% E-Value: 2.22e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (14%) - MXAN_4645 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 5.48e-06

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (14%) - MXAN_1349 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 31% E-Value: 1.26e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (14%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 7.39e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (14%) - MXAN_4645 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 1.10e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (2)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Trans_reg_C

Please submit feedback about this entry to the curator