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The Microbial Protein Interaction Database

Interaction Evidences

asgD - phoP2 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1CWW4 Sensor protein asgD MXAN_6996	Q1D8M8 DNA-binding response regulator PhoP2 phoP2 MXAN_2778
CMR Search...	CMR Search...
GO MF: two-component sensor activity GO MF: ATP binding GO MF: two-component response regulator activity GO CC: membrane GO BP: regulation of transcription, DNA-dependent GO BP: peptidyl-histidine phosphorylation GO BP: two-component signal transduction system (p...	GO MF: DNA binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (168)

Experiments (1)

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

Interologs (164)

asgD (87%) - phoP3 (57%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 71% Positives: 78% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (18%) - phoP2 (94%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 41% Positives: 50% E-Value: 1.22e-80

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (87%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 40% Positives: 46% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (87%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 37% Positives: 45% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (87%) - nla28 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 36% Positives: 44% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (87%) - MXAN_7396 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 50% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (87%) - MXAN_4645 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 41% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (87%) - pilR (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 34% Positives: 42% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (87%) - MXAN_7143 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 33% Positives: 43% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (10%) - phoP2 (94%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 37% E-Value: 3.11e-76

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - phoP2 (94%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 33% E-Value: 8.48e-66

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7398 (18%) - MXAN_4164 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 36% E-Value: 9.15e-32

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (6%) - phoP2 (94%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 31% E-Value: 1.45e-65

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (5%) - phoP2 (94%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 29% E-Value: 3.81e-66

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5313 (5%) - phoP2 (94%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 27% E-Value: 2.64e-67

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - phoP3 (57%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 28% E-Value: 6.12e-40

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (94%) - phoP2 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 27% E-Value: 1.22e-64

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (11%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 25% E-Value: 3.72e-29

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7059 (11%) - MXAN_4164 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 27% E-Value: 3.72e-29

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (10%) - MXAN_5313 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 27% E-Value: 4.25e-29

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (10%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 26% E-Value: 4.55e-27

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (11%) - MXAN_1680 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 24% E-Value: 1.37e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (11%) - MXAN_5212 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 6.35e-25

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (8%) - MXAN_5313 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 24% E-Value: 7.03e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

yycG (7%) - yycF (33%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 1.92e-17

Method	DB Source	Type	Publication
enzymatic study		physical association	Fukuchi K et al. (2000)

MXAN_7398 (18%) - MXAN_0460 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 1.24e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (18%) - MXAN_4645 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 6.57e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - MXAN_1349 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 8.04e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (18%) - MXAN_7363 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 5.75e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_4164 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 1.24e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - MXAN_5313 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 1.16e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - phoP1 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 2.42e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

kdpD (8%) - kdpE (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 4.27e-17

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Luttmann D et al. (2009)
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)
enzymatic study		physical association	Heermann R et al. (2003)
protein kinase assay		physical association	Luttmann D et al. (2009)

phoR1 (7%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 6.37e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 2.42e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 1.24e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (18%) - MXAN_5853 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 1.98e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (8%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 5.39e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1475 (7%) - slr1584 (31%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 1.47e-17

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

CcaS (7%) - slr1584 (31%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 1.47e-17

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation reaction	Hirose Y et al. (2008)

MXAN_7059 (11%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 19% E-Value: 5.57e-21

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sdeK (10%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 19% E-Value: 3.49e-19

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4164 (34%) - MXAN_4164 (6%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 7.52e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (5%) - MXAN_4164 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 2.50e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr0533 (5%) - sll0649 (33%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 7.28e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

phoP (34%) - phoP (5%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 3.38e-18

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

cpxR (33%) - cpxR (5%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 2.42e-16

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2606 (5%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 5.57e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (11%) - MXAN_7396 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 1.37e-19

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_3450 (32%) - MXAN_3450 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 18% E-Value: 9.20e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (5%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 2.86e-17

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1680 (5%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 2.50e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (7%) - MXAN_1680 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 4.42e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (5%) - MXAN_1349 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 3.61e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (11%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 18% E-Value: 3.26e-21

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (5%) - MXAN_4164 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 2.86e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (5%) - MXAN_5313 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 1.68e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (5%) - MXAN_5313 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 3.99e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

yedW (30%) - yedW (5%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 2.05e-15

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (32%) - ompR (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 8.04e-20

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (5%) - ompR (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 2.05e-19

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (4%) - phoB (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.92e-17

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (33%) - phoB (5%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 4.88e-17

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

arcA (31%) - arcA (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.24e-16

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (32%) - cusR (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 7.04e-16

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

yedW (5%) - cusR (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 4.27e-17

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_7059 (11%) - asgD (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 1.79e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (5%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 1.79e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (5%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 9.20e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (5%) - MXAN_1680 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 3.38e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 9.53e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (10%) - asgD (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 1.12e-17

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sdeK (10%) - MXAN_7396 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 8.60e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (5%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 4.27e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 1.86e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_3450 (5%) - MXAN_5212 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 1.57e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (8%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 5.77e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (6%) - MXAN_1680 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 2.77e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (4%) - MXAN_5313 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.68e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7024 (5%) - MXAN_5212 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 8.33e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (10%) - MXAN_5853 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 5.04e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0797 (27%) - sll0797 (4%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 3.74e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2098 (7%) - slr2100 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 2.59e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

qseB (29%) - qseB (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 7.53e-14

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

baeR (31%) - baeR (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 9.84e-14

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (4%) - yedW (30%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 3.38e-14

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_1350 (7%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 1.80e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilR (5%) - MXAN_1680 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 3.38e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (10%) - MXAN_7143 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 6.58e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 5.58e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (16%) - MXAN_2785 (8%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 1.09e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (8%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 3.38e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (18%) - MXAN_2606 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 4.28e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

cheB1 (5%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 14% E-Value: 9.22e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (5%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 13% E-Value: 1.38e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1350 (7%) - MXAN_0460 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 1.62e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (14%) - MXAN_0460 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 4.57e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1350 (7%) - pilR (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 3.39e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - MXAN_7396 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 2.35e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - MXAN_0460 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 8.62e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (7%) - MXAN_4645 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 8.63e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - asgD (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 5.97e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_7396 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 4.57e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_4645 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 8.92e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - MXAN_7363 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 4.00e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_7363 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 7.80e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (6%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 1.13e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (8%) - MXAN_0460 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 3.74e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_0459 (8%) - MXAN_5853 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 5.97e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1229 (5%) - sll1228 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 7.54e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2104 (5%) - slr1305 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 3.87e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (6%) - slr2104 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 3.06e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1905 (6%) - slr1305 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 1.62e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (6%) - sll1905 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 1.24e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll0649 (5%) - sll1592 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 5.40e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcB (6%) - hnr (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 2.68e-07

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

arcB (6%) - cheY (14%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 2.05e-07

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

MXAN_7143 (6%) - asgD (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 5.23e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 7.06e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (5%) - MXAN_7396 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 1.05e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (5%) - MXAN_7396 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 3.39e-06

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (4%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 1.38e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilR (5%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 1.38e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (5%) - pilR (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 12% E-Value: 2.59e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (5%) - pilR (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 7.06e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - MXAN_7143 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 1.80e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (5%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 3.27e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7143 (6%) - MXAN_4645 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 7.80e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (5%) - MXAN_4645 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 2.05e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1349 (5%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 9.53e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 4.14e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (5%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 1.92e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (5%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 8.06e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (5%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 2.51e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (5%) - MXAN_7363 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.80e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (6%) - MXAN_7396 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 2.77e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (6%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 6.60e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (5%) - MXAN_4645 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 12% E-Value: 1.42e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (5%) - MXAN_7363 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 1.24e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheY (4%) - HP_0392 (14%) (Helicobacter pylori (Campylobacter pylori))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 2.35e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Rain JC et al. (2001)

sll1228 (5%) - sll1229 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 1.24e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1594 (4%) - slr1759 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 2.59e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1353 (4%) - sll1905 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 9.53e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

slr1760 (5%) - slr1759 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 2.35e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2100 (6%) - slr2098 (12%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 3.74e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

glnG (12%) - glnG (6%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 2.77e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Salinas P et al. (2003)

MXAN_2606 (5%) - asgD (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 1.38e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (5%) - asgD (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 2.96e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (5%) - MXAN_7396 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 16% E-Value: 2.27e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP3 (5%) - asgD (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 3.50e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (4%) - MXAN_7396 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 3.39e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (5%) - asgD (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 4.43e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (5%) - MXAN_7396 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 16% E-Value: 3.39e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - pilR (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 1.33e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (5%) - pilR (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 8.06e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (5%) - MXAN_7143 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 6.17e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (5%) - asgD (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.05e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (5%) - MXAN_7396 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 15% E-Value: 8.06e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5995 (5%) - MXAN_4645 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 3.39e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (5%) - pilR (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 5.58e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (5%) - MXAN_5853 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.99e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (4%) - MXAN_5853 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 13% E-Value: 1.99e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (5%) - MXAN_5853 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 8% Positives: 14% E-Value: 6.17e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (4%) - MXAN_7143 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 7% Positives: 13% E-Value: 2.59e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (3)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Trans_reg_C
structural domain contact	3DID	predicted interaction	Response_reg	HisKA

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