The Microbial Protein Interaction Database

physical association

MXAN_5853 (96%) - MXAN_5996 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 36% Positives: 46% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (96%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 44% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (12%) - MXAN_0459 (92%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 34% Positives: 44% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_5853 (96%) - MXAN_6688 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 37% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

zraR (43%) - zraS (20%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 29% Positives: 41% E-Value: 3.27e-65

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

MXAN_5995 (8%) - MXAN_0459 (92%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 36% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (38%) - MXAN_7206 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 38% E-Value: 1.86e-56

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (38%) - pilS (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 39% E-Value: 7.53e-62

Method

DB Source

Type

Publication

physical association

MXAN_7143 (43%) - phoR1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 38% E-Value: 1.25e-52

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (43%) - sdeK (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 39% E-Value: 2.20e-53

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (43%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 37% E-Value: 3.87e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

nla28 (43%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 38% E-Value: 9.21e-56

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (38%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 35% E-Value: 1.47e-53

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

glnG (40%) - glnL (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 24% Positives: 37% E-Value: 1.99e-54

Method

DB Source

Type

Publication

physical association

Salinas P et al. (2003)

MXAN_7143 (43%) - phoR3 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 35% E-Value: 2.20e-49

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (38%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 36% E-Value: 2.87e-53

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (38%) - MXAN_1350 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 35% E-Value: 2.96e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (38%) - MXAN_3451 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 32% E-Value: 3.28e-49

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (38%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 32% E-Value: 7.07e-48

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

nifA (32%) - nifL (14%) (Azotobacter vinelandii)

Geometric mean of BLAST Identity: 21% Positives: 30% E-Value: 1.09e-44

Method

DB Source

Type

Publication

physical association

Lei S et al. (1999)

MXAN_0460 (12%) - MXAN_7206 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 1.54e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1529 (15%) - sll1672 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 4.47e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_0460 (12%) - MXAN_7398 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 1.03e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (12%) - pilS (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 3.09e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1529 (15%) - cph1 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 1.22e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1905 (14%) - sll1353 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 2.54e-09

Method

DB Source

Type

Publication

physical association

MXAN_0460 (12%) - MXAN_1350 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 2.45e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP3 (11%) - phoR1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 2.81e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (12%) - phoR1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 3.92e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (12%) - phoR1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 1.94e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (12%) - sdeK (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 3.43e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (12%) - MXAN_7363 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 1.70e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (12%) - MXAN_0461 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 4.94e-17

Method

DB Source

Type

Publication

physical association

phoP3 (11%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 8.72e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_7206 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 2.99e-18

Method

DB Source

Type

Publication

physical association

MXAN_2606 (9%) - pilS (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 1.21e-23

Method

DB Source

Type

Publication

physical association

MXAN_3450 (8%) - MXAN_7206 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 6.67e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - pilS (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 2.71e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (12%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 5.85e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (12%) - phoR3 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 3.43e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1400 (10%) - sll0474 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 3.79e-13

Method

DB Source

Type

Publication

physical association

A2VGV6 (9%) - kdpD (15%) (Mycobacterium tuberculosis C - Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 5.47e-12

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Davey CA et al. (2002)

ompR (12%) - envZ (12%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 5.12e-10

Method	DB Source	Type	Publication
electrophoretic mobility shift assay		physical association	Harlocker SL et al. (1995)
far western blotting		physical association	Cai SJ et al. (2002)
pull down		physical association	Cai SJ et al. (2002)

MXAN_2606 (9%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 2.37e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_7059 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 5.11e-14

Method

DB Source

Type

Publication

physical association

MXAN_2606 (16%) - MXAN_2606 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 4.63e-15

Method

DB Source

Type

Publication

physical association

MXAN_7396 (7%) - MXAN_7206 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 2.45e-16

Method

DB Source

Type

Publication

physical association

MXAN_7396 (7%) - pilS (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 9.95e-22

Method

DB Source

Type

Publication

physical association

MXAN_2606 (9%) - MXAN_1350 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 4.78e-16

Method

DB Source

Type

Publication

physical association

phoP2 (8%) - MXAN_7206 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 6.45e-17

Method

DB Source

Type

Publication

physical association

phoP2 (8%) - pilS (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 2.62e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (8%) - MXAN_7398 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 4.33e-13

Method

DB Source

Type

Publication

physical association

MXAN_1680 (7%) - MXAN_7206 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 5.46e-16

Method

DB Source

Type

Publication

physical association

MXAN_1680 (7%) - pilS (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 2.22e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - phoR1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 1.70e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - phoR1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 7.63e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (8%) - sdeK (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.94e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (8%) - sdeK (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 2.90e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - sdeK (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.35e-14

Method

DB Source

Type

Publication

physical association

MXAN_2785 (7%) - MXAN_7206 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.26e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (8%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 2.30e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 3.54e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.59e-15

Method

DB Source

Type

Publication

physical association

MXAN_5212 (9%) - MXAN_7059 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 2.62e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_7363 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 6.68e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_7206 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 4.18e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP1 (9%) - phoR1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 2.22e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cpxR (8%) - cpxA (14%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 3.32e-09

Method	DB Source	Type	Publication
unspecified method		physical association	Nakayama S et al. (2003)

sll1229 (8%) - sll1228 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.71e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1909 (9%) - slr0210 (12%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 5.66e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1760 (8%) - slr1759 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 7.39e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

yycF (8%) - yycG (13%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.46e-12

Method	DB Source	Type	Publication
enzymatic study		physical association	Fukuchi K et al. (2000)

spo0F (8%) - kinA (17%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 1.39e-19

Method	DB Source	Type	Publication
genetic interference		physical association	Stephenson SJ et al. (2002)

MXAN_5995 (8%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 6.68e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 1.14e-09

Method

DB Source

Type

Publication

physical association

MXAN_7396 (7%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 1.94e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (7%) - MXAN_7059 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 4.19e-12

Method

DB Source

Type

Publication

physical association

MXAN_7396 (7%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 3.79e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_5314 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.90e-09

Method

DB Source

Type

Publication

physical association

MXAN_3450 (8%) - MXAN_7059 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 1.14e-13

Method

DB Source

Type

Publication

physical association

MXAN_3450 (8%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 1.03e-14

Method

DB Source

Type

Publication

physical association

MXAN_3450 (8%) - MXAN_5314 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 6.47e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (7%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 2.54e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (7%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 4.95e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (7%) - MXAN_7398 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.15e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (12%) - MXAN_6688 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 6.46e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - phoR3 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 1.35e-10

Method

DB Source

Type

Publication

physical association

phoP2 (8%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 5.11e-14

Method

DB Source

Type

Publication

physical association

phoP2 (8%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 9.97e-14

Method

DB Source

Type

Publication

physical association

MXAN_7396 (7%) - phoR1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 6.25e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (8%) - phoR1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 1.65e-12

Method

DB Source

Type

Publication

physical association

MXAN_7396 (7%) - sdeK (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 1.10e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_1166 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 8.73e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - MXAN_3451 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 1.18e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_3451 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 5.29e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (8%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.54e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (8%) - phoR1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 4.19e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (7%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 9.97e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (7%) - phoR1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 3.21e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (7%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 1.30e-13

Method

DB Source

Type

Publication

physical association

MXAN_2785 (18%) - MXAN_2785 (7%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 6.68e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_3606 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 1.88e-12

Method

DB Source

Type

Publication

physical association

MXAN_5212 (9%) - MXAN_3606 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 9.64e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (7%) - MXAN_7363 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 2.81e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_7059 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 7.14e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 6.46e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_7398 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.81e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.22e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5212 (9%) - MXAN_5996 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 2.63e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_5996 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 5.12e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_7142 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 9.64e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1305 (8%) - slr2104 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 4.95e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (8%) - sll1905 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 1.95e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll0789 (7%) - sll0790 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 2.30e-10

Method

DB Source

Type

Publication

physical association

prrA (7%) - prrB (14%) (Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 2.90e-09

Method	DB Source	Type	Publication
enzymatic study		direct interaction	Nowak E et al. (2006)

kdpE (8%) - kdpD (13%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 5.47e-12

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Luttmann D et al. (2009)
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)
enzymatic study		physical association	Heermann R et al. (2003)
protein kinase assay		physical association	Luttmann D et al. (2009)

torR (7%) - torS (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 8.16e-12

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

MXAN_7396 (7%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 9.34e-08

Method

DB Source

Type

Publication

physical association

MXAN_7396 (7%) - MXAN_5314 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 2.38e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (8%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 2.54e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (7%) - phoR3 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 1.10e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (8%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 2.46e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (8%) - phoR3 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 2.90e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (7%) - MXAN_7059 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 9.33e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (7%) - MXAN_1350 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 8.72e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (8%) - MXAN_3451 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 1.14e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (7%) - MXAN_7059 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 2.15e-12

Method

DB Source

Type

Publication

physical association

MXAN_2785 (7%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 1.94e-13

Method

DB Source

Type

Publication

physical association

MXAN_4164 (7%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 16% E-Value: 1.59e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_4165 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 1.65e-08

Method

DB Source

Type

Publication

physical association

MXAN_7396 (7%) - MXAN_5996 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 4.19e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (7%) - MXAN_5996 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 7.15e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (7%) - MXAN_5996 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 2.15e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (7%) - MXAN_5996 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 9.34e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

regA (7%) - regB (14%) (Rhodobacter sphaeroides (strain ATCC 17023 / 241 / NCIB 8253 / DSM158))

Geometric mean of BLAST Identity: 10% Positives: 17% E-Value: 4.95e-09

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Potter CA et al. (2006)

regR (6%) - regS (14%) (Bradyrhizobium japonicum)

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 1.65e-08

Method	DB Source	Type	Publication
affinity chromatography technology		physical association	Emmerich R et al. (1999)

basR (7%) - basS (13%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 2.08e-07

Method	DB Source	Type	Publication
coimmunoprecipitation		physical association	Kato A et al. (2004)

slr1783 (9%) - slr1147 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 3.11e-07

Method

DB Source

Type

Publication

physical association

basR (7%) - basS (13%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 9% Positives: 15% E-Value: 1.59e-07

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

MXAN_5995 (8%) - MXAN_6688 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.82e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_6688 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 1.26e-12

Method

DB Source

Type

Publication

physical association

phoP2 (8%) - MXAN_6688 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 14% E-Value: 2.71e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (7%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 2.08e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (8%) - MXAN_6688 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 13% E-Value: 6.91e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (7%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 16% E-Value: 4.79e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1584 (8%) - sll1475 (8%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 8% Positives: 12% E-Value: 3.21e-08

Method

DB Source

Type

Publication

physical association