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The Microbial Protein Interaction Database

Interaction Evidences

phoP2 - MXAN_4072 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1D8M8 DNA-binding response regulator PhoP2 phoP2 MXAN_2778	Q1D523 DNA-binding response regulator, LuxR family MXAN_4072
CMR Search...	CMR Search...
GO MF: DNA binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: transcription factor activity GO MF: sequence-specific DNA binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (20)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (16)

phoP2 (94%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 45% Positives: 61% E-Value: 1.35e-68

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (18%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 38% Positives: 44% E-Value: 6.28e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (16%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 43% E-Value: 3.68e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (14%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 34% Positives: 45% E-Value: 5.68e-55

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (13%) - MXAN_4072 (80%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 32% Positives: 42% E-Value: 9.07e-53

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0649 (33%) - sll1592 (25%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 29% Positives: 43% E-Value: 5.73e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_5995 (31%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 36% E-Value: 2.41e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (32%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 36% E-Value: 1.24e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (18%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 31% E-Value: 1.51e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

bvgS (17%) - bvgA (20%) (Bordetella pertussis)

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 5.95e-08

Method	DB Source	Type	Publication
genetic interference		physical association	Merkel TJ et al. (2003)

MXAN_7396 (14%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 34% E-Value: 3.73e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (18%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 26% E-Value: 1.85e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (13%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 30% E-Value: 4.87e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (13%) - MXAN_6149 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 30% E-Value: 2.19e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (13%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 5.95e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (14%) - fruA (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 29% E-Value: 4.56e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (3)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Trans_reg_C
structural domain contact	3DID	predicted interaction	Response_reg	GerE

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