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The Microbial Protein Interaction Database

Interaction Evidences

phoR3 - MXAN_5313 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1CYI5 Sensor protein phoR3 MXAN_6414	Q1D1K9 DNA-binding response regulator MXAN_5313
CMR Search...	CMR Search...
GO MF: two-component sensor activity GO MF: ATP binding GO CC: membrane GO BP: signal transduction GO BP: peptidyl-histidine phosphorylation	GO MF: DNA binding GO MF: two-component response regulator activity GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (119)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (117)

phoR3 (84%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 51% Positives: 61% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (84%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 40% Positives: 48% E-Value: 0

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoR3 (84%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 38% Positives: 45% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (84%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 38% Positives: 46% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (42%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 37% Positives: 50% E-Value: 7.38e-71

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoR3 (84%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 37% Positives: 46% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (42%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 36% Positives: 49% E-Value: 1.39e-69

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (84%) - MXAN_5889 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 36% Positives: 43% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (11%) - MXAN_5313 (82%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 38% E-Value: 6.70e-56

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_5313 (82%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 39% E-Value: 1.54e-56

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (11%) - MXAN_5313 (82%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 37% E-Value: 2.55e-55

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (11%) - MXAN_5313 (82%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 37% E-Value: 1.44e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (42%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 29% Positives: 39% E-Value: 1.88e-66

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoR2 (42%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 36% E-Value: 3.55e-65

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (42%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 37% E-Value: 9.03e-65

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (12%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 29% E-Value: 1.67e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - phoP1 (37%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 31% E-Value: 8.55e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (12%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 27% E-Value: 6.13e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - phoP3 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 28% E-Value: 2.41e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 29% E-Value: 2.57e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_1349 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 29% E-Value: 1.01e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

prrB (11%) - prrA (34%) (Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 19% Positives: 27% E-Value: 3.98e-16

Method	DB Source	Type	Publication
enzymatic study		direct interaction	Nowak E et al. (2006)

asgD (11%) - phoP3 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 27% E-Value: 7.50e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (11%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 4.25e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (12%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 27% E-Value: 1.16e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 4.86e-18

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sdeK (11%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 27% E-Value: 5.74e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (11%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 26% E-Value: 1.32e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (11%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 25% E-Value: 2.49e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (11%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 30% E-Value: 1.56e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 2.18e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

yycG (10%) - yycF (34%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 3.84e-19

Method	DB Source	Type	Publication
enzymatic study		physical association	Fukuchi K et al. (2000)

kdpD (11%) - kdpE (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 8.01e-17

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Luttmann D et al. (2009)
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)
enzymatic study		physical association	Heermann R et al. (2003)
protein kinase assay		physical association	Luttmann D et al. (2009)

MXAN_2606 (10%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 26% E-Value: 1.91e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 8.01e-17

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7398 (11%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 1.08e-17

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (11%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 1.51e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilS (11%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 8.01e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (11%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 4.54e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - MXAN_1349 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 3.15e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

kdpD (11%) - A2VGV6 (27%) (Mycobacterium tuberculosis C - Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 17% Positives: 26% E-Value: 1.85e-13

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Davey CA et al. (2002)

yedV (9%) - yedW (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 17% Positives: 26% E-Value: 6.56e-15

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

MXAN_2606 (10%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 26% E-Value: 1.51e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (11%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 2.04e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (12%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 20% E-Value: 2.95e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (12%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 1.56e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilS (11%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 1.08e-13

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1350 (12%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 3.72e-18

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5211 (12%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 20% E-Value: 3.37e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (11%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 1.01e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (12%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 1.46e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (12%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 3.48e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 6.56e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (11%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 6.14e-13

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1166 (11%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 1.73e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (11%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 20% E-Value: 3.37e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (12%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 1.37e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (12%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 20% E-Value: 8.58e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 3.60e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (11%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 2.85e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0474 (10%) - slr1400 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 9.48e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

sll1003 (10%) - slr1909 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 3.85e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1393 (11%) - slr1037 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 7.02e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

pleC (9%) - pleD (20%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 1.08e-13

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

divJ (10%) - pleD (20%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 2.41e-13

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

MXAN_2606 (19%) - MXAN_2606 (10%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 2.04e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (11%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 9.81e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (12%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 7.51e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (11%) - nla28 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 1.01e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (11%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 2.04e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilS (11%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 5.20e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1350 (12%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 8.01e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (12%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 1.28e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (12%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 3.04e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 6.14e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 3.15e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (12%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 1.41e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (11%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 1.16e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sdeK (11%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 2.95e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (11%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 18% E-Value: 2.76e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (11%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 1.79e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (12%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 3.25e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (11%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 1.12e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (11%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 1.56e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0798 (9%) - sll0797 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 1.20e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

sll1353 (9%) - sll1905 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 2.18e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

slr0210 (9%) - slr1909 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 2.04e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcB (9%) - cheY (17%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 3.37e-11

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

zraS (9%) - zraR (17%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 3.73e-10

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

asgD (11%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 1.91e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 3.85e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 9.81e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (11%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 8.03e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (11%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 5.75e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (12%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 1.46e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (11%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 3.15e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (11%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 1.67e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (11%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 8.87e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (10%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 1.67e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (11%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 5.75e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (11%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 1.28e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 1.79e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7398 (11%) - MXAN_5889 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 7.51e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 1.12e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5211 (12%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 4.71e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - frzZ (15%) (Myxococcus xanthus (strain DK 1622) - Myxococcus xanthus)

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 7.03e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sll1228 (9%) - sll1229 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 1.67e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1805 (9%) - sll1708 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 4.41e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

pleC (9%) - divK (15%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 7.03e-09

Method

DB Source

Type

Publication

dephosphorylation

phosphorylation

divJ (10%) - divK (15%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 1.57e-08

Method

DB Source

Type

Publication

protein kinase assay

phosphorylation

Paul R et al. (2008)

MXAN_2606 (10%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 8.03e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (11%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 4.40e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (10%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 6.15e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sdeK (11%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 1.85e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sasA (9%) - sll1291 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 6.15e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcB (9%) - hnr (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 6.36e-10

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

sasA (9%) - slr1594 (11%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 21% E-Value: 1.16e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

Domain-Domain Interactions (1)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID	predicted interaction	Response_reg	HisKA

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