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The Microbial Protein Interaction Database

Interaction Evidences

MXAN_4072 - MXAN_0459 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1D523 DNA-binding response regulator, LuxR family MXAN_4072	Q1DF44 Sensor protein MXAN_0459
CMR Search...	CMR Search...
GO MF: transcription factor activity GO MF: sequence-specific DNA binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: two-component sensor activity GO MF: ATP binding GO CC: membrane GO BP: signal transduction GO BP: peptidyl-histidine phosphorylation

List of evidences (22)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (20)

MXAN_4072 (80%) - MXAN_7206 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 39% Positives: 47% E-Value: 3.84e-62

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - MXAN_7398 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 38% Positives: 46% E-Value: 2.57e-58

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 38% Positives: 46% E-Value: 2.04e-59

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 44% E-Value: 5.93e-59

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - MXAN_3451 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 33% Positives: 40% E-Value: 6.78e-55

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (80%) - MXAN_6688 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 33% E-Value: 1.61e-56

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (22%) - MXAN_7398 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 32% E-Value: 6.21e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (22%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 7.33e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (22%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 31% E-Value: 1.43e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

bvgA (20%) - bvgS (13%) (Bordetella pertussis)

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 1.69e-09

Method	DB Source	Type	Publication
genetic interference		physical association	Merkel TJ et al. (2003)

sll1592 (25%) - slr1414 (10%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 6.00e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

fruA (17%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 8.96e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_7059 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 1.93e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_2606 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 1.75e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

fruA (17%) - MXAN_1350 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 1.81e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

zraR (11%) - zraS (20%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 9.89e-22

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

fruA (17%) - MXAN_5211 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 4.31e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_5314 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 1.10e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_4165 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 4.45e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fruA (17%) - MXAN_3451 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 2.00e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (1)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID	predicted interaction	Response_reg	HisKA

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