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The Microbial Protein Interaction Database

Interaction Evidences

MXAN_0460 - MXAN_6296 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1DF43 Response regulator MXAN_0460	Q1CYV2 Response regulator MXAN_6296
CMR Search...	CMR Search...
GO MF: two-component response regulator activity GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: two-component response regulator activity GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (58)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (56)

MXAN_3450 (25%) - MXAN_6296 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 50% Positives: 63% E-Value: 5.18e-42

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (21%) - MXAN_6296 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 46% Positives: 55% E-Value: 1.56e-42

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7143 (19%) - MXAN_6296 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 43% Positives: 56% E-Value: 5.36e-43

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (15%) - MXAN_6296 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 38% Positives: 48% E-Value: 6.77e-42

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (15%) - MXAN_6296 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 38% Positives: 52% E-Value: 1.32e-41

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (12%) - MXAN_6296 (100%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 43% E-Value: 7.24e-40

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (25%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 39% E-Value: 2.51e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilR (20%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 40% E-Value: 2.35e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoB (25%) - phoB (23%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 24% Positives: 41% E-Value: 2.20e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

glnG (27%) - glnG (19%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 23% Positives: 31% E-Value: 3.39e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Salinas P et al. (2003)

asgD (21%) - MXAN_7143 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 37% E-Value: 8.64e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (22%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 40% E-Value: 1.99e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (22%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 38% E-Value: 5.06e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (21%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 34% E-Value: 7.56e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (18%) - MXAN_7143 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 38% E-Value: 8.64e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (20%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 2.97e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (21%) - MXAN_4645 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 32% E-Value: 1.13e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (20%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 35% E-Value: 1.74e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (15%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 34% E-Value: 6.83e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (21%) - MXAN_4645 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 33% E-Value: 7.56e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1592 (15%) - sll0649 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 21% Positives: 36% E-Value: 1.25e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

phoP (28%) - phoP (16%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 21% Positives: 36% E-Value: 2.96e-13

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

cpxR (27%) - cpxR (16%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 8.93e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2606 (15%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 36% E-Value: 5.06e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (18%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 35% E-Value: 7.56e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4645 (14%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 31% E-Value: 5.79e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (19%) - MXAN_4645 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 33% E-Value: 3.88e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (15%) - MXAN_4164 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 33% E-Value: 6.83e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (16%) - MXAN_4164 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 35% E-Value: 2.87e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr2104 (16%) - slr1305 (26%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 20% Positives: 28% E-Value: 1.68e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1905 (15%) - slr1305 (26%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 20% Positives: 31% E-Value: 8.93e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

cheB1 (16%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 30% E-Value: 1.25e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (16%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 30% E-Value: 1.33e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (28%) - MXAN_4164 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 33% E-Value: 8.35e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (15%) - MXAN_4164 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 5.06e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

ompR (14%) - phoB (25%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 19% Positives: 32% E-Value: 3.88e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

creB (15%) - kdpE (25%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 19% Positives: 29% E-Value: 4.15e-07

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

baeR (25%) - baeR (15%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 19% Positives: 34% E-Value: 8.08e-07

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_5995 (15%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 30% E-Value: 3.28e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (24%) - MXAN_2606 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 32% E-Value: 6.40e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4645 (14%) - MXAN_7143 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 30% E-Value: 8.35e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (15%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 8.64e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (15%) - MXAN_4645 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 29% E-Value: 1.29e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (15%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 1.06e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

frzZ (13%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622) - Myxococcus xanthus)

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 2.06e-06

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sll1228 (14%) - sll1229 (23%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 7.31e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcA (23%) - arcA (13%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 9.55e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_4645 (14%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 7.31e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5995 (15%) - MXAN_4645 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 4.90e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (15%) - MXAN_4645 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 31% E-Value: 9.55e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (15%) - MXAN_1349 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 33% E-Value: 2.20e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4072 (14%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 31% E-Value: 3.17e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (12%) - MXAN_4164 (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 2.78e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1305 (12%) - sll1905 (25%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 29% E-Value: 1.68e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_7396 (12%) - MXAN_2606 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 3.51e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (12%) - MXAN_4645 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 5.24e-06

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

Domain-Domain Interactions (1)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg

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