The Microbial Protein Interaction Database

physical association

sdeK (91%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 40% Positives: 47% E-Value: 0

Method

DB Source

Type

Publication

physical association

MXAN_7363 (19%) - MXAN_5313 (82%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 40% Positives: 51% E-Value: 3.81e-58

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (91%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 39% Positives: 48% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (91%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 39% Positives: 48% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - MXAN_5313 (82%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 38% Positives: 48% E-Value: 7.43e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (17%) - MXAN_5313 (82%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 37% Positives: 46% E-Value: 5.69e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sdeK (91%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 47% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (12%) - MXAN_5313 (82%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 32% Positives: 39% E-Value: 2.23e-54

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (25%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 42% E-Value: 4.67e-40

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (25%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 39% E-Value: 1.72e-34

Method

DB Source

Type

Publication

physical association

MXAN_7059 (25%) - MXAN_5212 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 37% E-Value: 9.13e-32

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - phoP1 (37%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 38% E-Value: 4.11e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (19%) - phoP3 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 33% E-Value: 2.57e-30

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - MXAN_1349 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 36% E-Value: 4.87e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (19%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 33% E-Value: 5.18e-31

Method

DB Source

Type

Publication

physical association

phoR1 (18%) - phoP3 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 35% E-Value: 1.16e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 36% E-Value: 1.24e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (17%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 34% E-Value: 9.48e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (17%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 34% E-Value: 1.79e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 35% E-Value: 2.34e-15

Method

DB Source

Type

Publication

physical association

CcaS (18%) - slr1584 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 22% Positives: 37% E-Value: 4.40e-18

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation reaction	Hirose Y et al. (2008)

MXAN_7059 (25%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 31% E-Value: 4.39e-30

Method

DB Source

Type

Publication

physical association

MXAN_7059 (25%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 32% E-Value: 4.10e-32

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (14%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 32% E-Value: 1.61e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (13%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 32% E-Value: 3.36e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (25%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 29% E-Value: 8.27e-29

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (14%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 30% E-Value: 1.12e-17

Method

DB Source

Type

Publication

physical association

MXAN_2785 (13%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 30% E-Value: 1.24e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (25%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 29% E-Value: 2.41e-28

Method

DB Source

Type

Publication

physical association

MXAN_7206 (12%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 29% E-Value: 1.51e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1393 (21%) - slr1037 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 20% Positives: 30% E-Value: 9.18e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_7059 (25%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 29% E-Value: 2.11e-28

Method

DB Source

Type

Publication

physical association

MXAN_7206 (12%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 27% E-Value: 5.56e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (12%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 29% E-Value: 3.98e-15

Method

DB Source

Type

Publication

physical association

MXAN_7206 (12%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 27% E-Value: 1.05e-15

Method

DB Source

Type

Publication

physical association

phoR3 (12%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 28% E-Value: 7.03e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (12%) - MXAN_1349 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 29% E-Value: 2.26e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (13%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 29% E-Value: 2.95e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 29% E-Value: 3.85e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (12%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 31% E-Value: 1.56e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (12%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 1.37e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (19%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 26% E-Value: 7.00e-28

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (19%) - nla28 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 26% E-Value: 3.47e-27

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 27% E-Value: 1.42e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (12%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 29% E-Value: 5.75e-18

Method

DB Source

Type

Publication

physical association

phoR2 (12%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 7.52e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (12%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 1.08e-16

Method

DB Source

Type

Publication

physical association

phoR1 (18%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 3.16e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3606 (13%) - MXAN_5212 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 27% E-Value: 1.01e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (19%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 29% E-Value: 1.62e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (19%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 27% E-Value: 8.88e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (12%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 28% E-Value: 1.37e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

basS (11%) - basR (29%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 8.04e-12

Method	DB Source	Type	Publication
coimmunoprecipitation		physical association	Kato A et al. (2004)

slr0533 (10%) - sll0649 (35%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 18% Positives: 29% E-Value: 1.85e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

kdpD (12%) - A2VGV6 (27%) (Mycobacterium tuberculosis C - Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 18% Positives: 29% E-Value: 1.62e-12

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Davey CA et al. (2002)

creC (11%) - creB (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 18% Positives: 26% E-Value: 9.50e-13

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

asgD (19%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 25% E-Value: 6.55e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (19%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 25% E-Value: 3.36e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (17%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 2.42e-12

Method

DB Source

Type

Publication

physical association

MXAN_5211 (11%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 27% E-Value: 2.67e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (19%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 24% E-Value: 5.73e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (17%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 2.26e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (19%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 26% E-Value: 6.13e-28

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (19%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 24% E-Value: 3.84e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 26% E-Value: 1.73e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1475 (11%) - slr1584 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 29% E-Value: 4.12e-16

Method

DB Source

Type

Publication

physical association

sll0790 (10%) - sll0789 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 1.09e-12

Method

DB Source

Type

Publication

physical association

yedV (9%) - yedW (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 1.33e-14

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

basS (11%) - basR (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 17% Positives: 26% E-Value: 1.28e-13

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

kdpD (11%) - kdpE (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 8.03e-16

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Luttmann D et al. (2009)
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)
enzymatic study		physical association	Heermann R et al. (2003)
protein kinase assay		physical association	Luttmann D et al. (2009)

torS (10%) - torR (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 1.91e-13

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

asgD (19%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 23% E-Value: 2.75e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilS (17%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 4.56e-11

Method

DB Source

Type

Publication

physical association

pilS (17%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 1.16e-10

Method

DB Source

Type

Publication

physical association

pilS (17%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 25% E-Value: 1.98e-10

Method

DB Source

Type

Publication

physical association

phoR1 (18%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 2.96e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 1.52e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (18%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 6.81e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (8%) - MXAN_1349 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 22% E-Value: 7.03e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (8%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 24% E-Value: 4.86e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

yycG (7%) - yycF (34%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 1.98e-18

Method	DB Source	Type	Publication
enzymatic study		physical association	Fukuchi K et al. (2000)

arcB (15%) - cheY (17%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 16% Positives: 28% E-Value: 1.79e-11

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

MXAN_6688 (8%) - MXAN_5995 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 22% E-Value: 4.26e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (14%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 3.26e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (12%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 9.50e-13

Method

DB Source

Type

Publication

physical association

MXAN_6688 (8%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 22% E-Value: 3.37e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1166 (13%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 22% E-Value: 9.82e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (8%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 5.03e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (8%) - phoP2 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 9.48e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (14%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 24% E-Value: 1.33e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (13%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 23% E-Value: 3.15e-16

Method

DB Source

Type

Publication

physical association

MXAN_3606 (13%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 22% E-Value: 4.87e-13

Method

DB Source

Type

Publication

physical association

slr0210 (12%) - slr1909 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 1.05e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

pleC (11%) - pleD (20%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 1.51e-14

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

MXAN_2606 (19%) - MXAN_2606 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 1.46e-13

Method

DB Source

Type

Publication

physical association

MXAN_5211 (11%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 3.61e-12

Method

DB Source

Type

Publication

physical association

MXAN_7206 (12%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 1.42e-12

Method

DB Source

Type

Publication

physical association

MXAN_5314 (7%) - MXAN_3450 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 2.26e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (14%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 5.95e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (12%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 20% E-Value: 3.05e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (12%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 1.92e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (12%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 1.02e-10

Method

DB Source

Type

Publication

physical association

phoR3 (12%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 1.79e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (12%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 1.33e-14

Method

DB Source

Type

Publication

physical association

MXAN_5211 (11%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 3.37e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (12%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 1.24e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (14%) - MXAN_5889 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 21% E-Value: 7.78e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (13%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 5.95e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (13%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 1.51e-14

Method

DB Source

Type

Publication

physical association

MXAN_2785 (13%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 23% E-Value: 2.76e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (12%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 20% E-Value: 7.78e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (18%) - MXAN_2785 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 22% E-Value: 1.73e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1353 (10%) - sll1905 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 4.71e-12

Method

DB Source

Type

Publication

physical association

arcB (15%) - hnr (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 3.38e-10

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

MXAN_2606 (12%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 2.76e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 6.81e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 1.73e-10

Method

DB Source

Type

Publication

physical association

MXAN_2606 (12%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 7.03e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (12%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 6.81e-11

Method

DB Source

Type

Publication

physical association

MXAN_7206 (12%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 19% E-Value: 5.57e-09

Method

DB Source

Type

Publication

physical association

MXAN_1350 (10%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 5.95e-11

Method

DB Source

Type

Publication

physical association

MXAN_5211 (11%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 7.78e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (12%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 4.88e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (12%) - MXAN_7143 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 8.89e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (12%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 4.56e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (12%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 1.16e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (12%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 1.20e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (10%) - MXAN_1680 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 5.57e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 3.16e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (12%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 1.28e-13

Method

DB Source

Type

Publication

physical association

MXAN_7206 (12%) - MXAN_5889 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 19% E-Value: 7.28e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR3 (12%) - MXAN_5889 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 4.88e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 20% E-Value: 1.98e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (12%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 21% E-Value: 8.04e-12

Method

DB Source

Type

Publication

physical association

MXAN_7398 (14%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 4.56e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (12%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 3.16e-12

Method

DB Source

Type

Publication

physical association

MXAN_2606 (12%) - frzZ (15%) (Myxococcus xanthus (strain DK 1622) - Myxococcus xanthus)

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 5.04e-10

Method

DB Source

Type

Publication

physical association

sll0474 (8%) - slr1400 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 5.57e-13

Method

DB Source

Type

Publication

physical association

sll0798 (10%) - sll0797 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 1.09e-12

Method

DB Source

Type

Publication

physical association

sll1003 (8%) - slr1909 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 7.27e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1229 (10%) - sll1228 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 3.73e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (10%) - slr1760 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 1.09e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

glnL (9%) - glnG (19%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 1.16e-10

Method

DB Source

Type

Publication

physical association

Salinas P et al. (2003)

pleC (11%) - divK (15%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 9.83e-10

Method

DB Source

Type

Publication

dephosphorylation

phosphorylation

divJ (8%) - pleD (20%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 13% Positives: 18% E-Value: 1.28e-13

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

MXAN_2606 (12%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 5.76e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (10%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 1.28e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 2.96e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (10%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 4.88e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (8%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 19% E-Value: 1.28e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (10%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 5.21e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (12%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 4.27e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (12%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 4.41e-10

Method

DB Source

Type

Publication

physical association

MXAN_0459 (12%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 4.41e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (8%) - asgD (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 16% E-Value: 8.60e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (8%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 4.56e-11

Method

DB Source

Type

Publication

physical association

MXAN_6688 (8%) - MXAN_7396 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 2.19e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (10%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 2.34e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (8%) - MXAN_0460 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 9.83e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (8%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 17% E-Value: 1.05e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (8%) - MXAN_2785 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 16% E-Value: 2.50e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5211 (11%) - MXAN_5853 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 1.09e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (12%) - MXAN_4245 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.68e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1759 (10%) - slr1594 (11%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 3.50e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sphS (10%) - slr1594 (11%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 1.33e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sasA (8%) - sll1291 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 1.28e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1805 (8%) - sll1708 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 5.39e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

kinA (7%) - spo0F (16%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 2.26e-10

Method	DB Source	Type	Publication
genetic interference		physical association	Stephenson SJ et al. (2002)

zraS (8%) - zraR (17%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 2.50e-09

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

divJ (8%) - divK (15%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 8.32e-09

Method

DB Source

Type

Publication

protein kinase assay

phosphorylation

Paul R et al. (2008)

MXAN_6688 (8%) - cheB1 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 15% E-Value: 1.79e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5314 (7%) - MXAN_2606 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 5.76e-10

Method

DB Source

Type

Publication

physical association