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The Microbial Protein Interaction Database

Interaction Evidences

MXAN_7398 - MXAN_6149 ( Myxococcus xanthus (strain DK 1622) )

Protein A	Protein B
Q1CVR8 Sensor protein MXAN_7398	Q1CZ93 DNA-binding response regulator, LuxR family MXAN_6149
CMR Search...	CMR Search...
GO MF: two-component sensor activity GO MF: ATP binding GO CC: membrane GO BP: signal transduction GO BP: peptidyl-histidine phosphorylation	GO MF: transcription factor activity GO MF: sequence-specific DNA binding GO MF: two-component response regulator activity GO CC: intracellular GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (33)

Experiments (1)

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Interologs (31)

MXAN_7398 (79%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 46% Positives: 61% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7398 (79%) - MXAN_0460 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 36% Positives: 43% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (7%) - MXAN_6149 (93%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 32% E-Value: 2.25e-64

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (7%) - MXAN_6149 (93%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 31% E-Value: 1.27e-63

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (6%) - MXAN_6149 (93%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 31% E-Value: 3.71e-59

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

bvgS (7%) - bvgA (27%) (Bordetella pertussis)

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 7.83e-17

Method	DB Source	Type	Publication
genetic interference		physical association	Merkel TJ et al. (2003)

MXAN_7206 (8%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 6.86e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (7%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 1.63e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (8%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 1.74e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (8%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 23% E-Value: 6.63e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr0210 (7%) - slr1909 (23%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 8.96e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcB (7%) - hnr (24%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 13% Positives: 21% E-Value: 2.52e-11

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

phoR2 (6%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 4.75e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1805 (5%) - sll1708 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 5.08e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

evgS (6%) - evgA (25%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 3.76e-15

Method	DB Source	Type	Publication
surface plasmon resonance		physical association	Perraud AL et al. (2000)
surface plasmon resonance		physical association	Tanabe H et al. (1998)

asgD (7%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.48e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7059 (8%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 6.42e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (7%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 8.38e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5211 (7%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 18% E-Value: 1.25e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (7%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 5.80e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (6%) - MXAN_4072 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 4.75e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

prrB (5%) - prrA (24%) (Mycobacterium tuberculosis)

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 4.92e-07

Method	DB Source	Type	Publication
enzymatic study		direct interaction	Nowak E et al. (2006)

MXAN_5314 (7%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 3.19e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (8%) - MXAN_0460 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 5.09e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1350 (7%) - MXAN_0460 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 17% E-Value: 8.38e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4165 (6%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 1.75e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (7%) - MXAN_0460 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 6.86e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3451 (6%) - fruA (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 18% E-Value: 2.44e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (8%) - MXAN_0460 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 16% E-Value: 4.92e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sll1003 (5%) - slr1909 (23%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 21% E-Value: 2.61e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_5211 (7%) - MXAN_0460 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 15% E-Value: 1.81e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (1)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID	predicted interaction	Response_reg	HisKA

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