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The Microbial Protein Interaction Database

Interaction Evidences

cusR - cusR ( Escherichia coli (strain K12) )

Protein A	Protein B
P0ACZ8 Transcriptional regulatory protein cusR cusR b0571, JW0560	P0ACZ8 Transcriptional regulatory protein cusR cusR b0571, JW0560
CMR Search...	CMR Search...
GO MF: DNA binding GO MF: copper ion binding GO MF: two-component response regulator activity GO CC: cytoplasm GO BP: sensory perception GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: DNA binding GO MF: copper ion binding GO MF: two-component response regulator activity GO CC: cytoplasm GO BP: sensory perception GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (162)

Experiments (1)

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

Interologs (158)

cusR (100%) - yedW (50%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 71% Positives: 85% E-Value: 6.48e-94

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

yedW (50%) - cusR (100%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 71% Positives: 85% E-Value: 6.48e-94

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

yedW (50%) - yedW (50%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 50% Positives: 72% E-Value: 6.54e-62

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_3450 (41%) - MXAN_3450 (41%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 41% Positives: 54% E-Value: 1.37e-35

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP (40%) - phoP (40%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 40% Positives: 58% E-Value: 6.59e-38

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

qseB (39%) - qseB (39%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 39% Positives: 59% E-Value: 1.57e-39

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (38%) - ompR (38%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 38% Positives: 56% E-Value: 1.29e-33

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoP2 (37%) - phoP2 (37%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 37% Positives: 52% E-Value: 1.09e-32

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoB (33%) - ompR (38%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 36% Positives: 55% E-Value: 9.52e-33

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (38%) - phoB (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 36% Positives: 55% E-Value: 9.52e-33

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_5212 (31%) - MXAN_3450 (41%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 36% Positives: 53% E-Value: 1.42e-32

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (41%) - MXAN_5212 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 36% Positives: 53% E-Value: 1.42e-32

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (36%) - MXAN_4164 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 36% Positives: 54% E-Value: 1.42e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

creB (35%) - creB (35%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 35% Positives: 53% E-Value: 8.62e-30

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpE (34%) - creB (35%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 35% Positives: 53% E-Value: 8.34e-29

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

creB (35%) - kdpE (34%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 35% Positives: 53% E-Value: 8.34e-29

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_1680 (30%) - MXAN_3450 (41%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 52% E-Value: 2.43e-28

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (41%) - MXAN_1680 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 52% E-Value: 2.43e-28

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (33%) - phoP2 (37%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 54% E-Value: 1.24e-32

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (37%) - MXAN_5313 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 54% E-Value: 1.24e-32

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cpxR (34%) - cpxR (34%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 34% Positives: 55% E-Value: 1.05e-27

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

rstA (33%) - kdpE (34%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 34% Positives: 53% E-Value: 2.68e-27

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpE (34%) - rstA (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 34% Positives: 53% E-Value: 2.68e-27

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

sll0797 (33%) - sll0797 (33%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 33% Positives: 56% E-Value: 2.68e-31

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

phoB (33%) - phoB (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 54% E-Value: 7.05e-32

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

rstA (33%) - rstA (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 53% E-Value: 8.92e-27

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

baeR (33%) - baeR (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 52% E-Value: 2.20e-25

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_4164 (36%) - MXAN_1680 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 33% Positives: 52% E-Value: 7.82e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (30%) - MXAN_4164 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 33% Positives: 52% E-Value: 7.82e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

torR (32%) - torR (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 32% Positives: 50% E-Value: 1.09e-24

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoP (32%) - phoP (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 32% Positives: 57% E-Value: 2.96e-30

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)
molecular sieving		physical association	Bachhawat P et al. (2007)
x-ray crystallography		physical association	Bachhawat P et al. (2007)

arcA (29%) - arcA (29%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 29% Positives: 47% E-Value: 3.07e-19

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_3450 (41%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 29% Positives: 43% E-Value: 4.28e-25

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_3450 (41%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 29% Positives: 43% E-Value: 4.28e-25

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_3450 (41%) - MXAN_7396 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 44% E-Value: 8.93e-23

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (19%) - MXAN_3450 (41%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 44% E-Value: 8.93e-23

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (37%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 43% E-Value: 1.21e-23

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - phoP2 (37%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 43% E-Value: 1.21e-23

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1349 (36%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 44% E-Value: 8.63e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_1349 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 44% E-Value: 8.63e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (37%) - MXAN_7396 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 43% E-Value: 2.51e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (19%) - phoP2 (37%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 43% E-Value: 2.51e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (36%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 43% E-Value: 1.38e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_4164 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 43% E-Value: 1.38e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (18%) - MXAN_3450 (41%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 39% E-Value: 4.15e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (41%) - MXAN_5853 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 39% E-Value: 4.15e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_5995 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 43% E-Value: 2.69e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (32%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 43% E-Value: 2.69e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (37%) - MXAN_6149 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 40% E-Value: 5.42e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (19%) - phoP2 (37%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 40% E-Value: 5.42e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (36%) - MXAN_7396 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 44% E-Value: 2.88e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (19%) - MXAN_4164 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 44% E-Value: 2.88e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (18%) - phoP2 (37%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 38% E-Value: 1.17e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (37%) - MXAN_5853 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 38% E-Value: 1.17e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP3 (37%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 39% E-Value: 1.99e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (17%) - phoP3 (37%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 39% E-Value: 1.99e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (37%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 39% E-Value: 9.25e-20

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (17%) - phoP2 (37%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 39% E-Value: 9.25e-20

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilR (16%) - MXAN_3450 (41%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 37% E-Value: 1.74e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (41%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 37% E-Value: 1.74e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (14%) - MXAN_3450 (41%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 39% E-Value: 2.60e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (41%) - MXAN_2785 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 39% E-Value: 2.60e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5212 (31%) - MXAN_7396 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 43% E-Value: 9.25e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (19%) - MXAN_5212 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 43% E-Value: 9.25e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (37%) - MXAN_7143 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 37% E-Value: 1.86e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (14%) - phoP2 (37%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 37% E-Value: 1.86e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (16%) - MXAN_5995 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 37% E-Value: 1.09e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (32%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 37% E-Value: 1.09e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (33%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 37% E-Value: 5.60e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (33%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 40% E-Value: 3.88e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (33%) - MXAN_7363 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 38% E-Value: 9.25e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (15%) - MXAN_5313 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 38% E-Value: 9.25e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (16%) - MXAN_5313 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 37% E-Value: 5.60e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (15%) - MXAN_5313 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 40% E-Value: 3.88e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (30%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 3.08e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (16%) - MXAN_1680 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 3.08e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (15%) - MXAN_5995 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 39% E-Value: 7.57e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (32%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 39% E-Value: 7.57e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (36%) - MXAN_2785 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 39% E-Value: 8.37e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (14%) - MXAN_4164 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 39% E-Value: 8.37e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 35% E-Value: 1.34e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (14%) - MXAN_5995 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 39% E-Value: 1.63e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (32%) - MXAN_2785 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 39% E-Value: 1.63e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (19%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 2.79e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_7396 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 2.79e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (19%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 32% E-Value: 6.01e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_6149 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 32% E-Value: 6.01e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr2024 (19%) - slr2024 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 19% Positives: 38% E-Value: 3.19e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_2606 (21%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 32% E-Value: 1.02e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (17%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 32% E-Value: 1.02e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (19%) - MXAN_7396 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 32% E-Value: 1.25e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (19%) - MXAN_6149 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 32% E-Value: 1.25e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (19%) - MXAN_0460 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 2.88e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5853 (18%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 1.29e-13

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_5853 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 1.29e-13

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

frzZ (15%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622) - Myxococcus xanthus)

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 2.06e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - frzZ (15%) (Myxococcus xanthus (strain DK 1622) - Myxococcus xanthus)

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 2.06e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

TP_0519 (18%) - TP_0519 (18%) (Treponema pallidum)

Geometric mean of BLAST Identity: 18% Positives: 31% E-Value: 7.09e-16

Method

DB Source

Type

Publication

two hybrid array

physical association

Titz B et al. (2008)

MXAN_7396 (19%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 2.14e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (17%) - MXAN_7396 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 2.14e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (19%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 4.60e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (17%) - MXAN_6149 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 4.60e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (16%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 5.43e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 5.43e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (15%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 3.76e-13

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 3.76e-13

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7363 (15%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 8.97e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_7363 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 8.97e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (18%) - MXAN_6149 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 29% E-Value: 5.81e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (19%) - MXAN_5853 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 29% E-Value: 5.81e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1228 (19%) - sll1229 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 1.53e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1229 (16%) - sll1228 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 1.53e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2100 (20%) - slr2098 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 3.52e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2098 (15%) - slr2100 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 3.52e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_0460 (19%) - frzZ (15%) (Myxococcus xanthus - Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 9.59e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

frzZ (15%) - MXAN_0460 (19%) (Myxococcus xanthus - Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 9.59e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (16%) - MXAN_7396 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 30% E-Value: 1.13e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (19%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 30% E-Value: 1.13e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (15%) - MXAN_7396 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 32% E-Value: 7.84e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (19%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 32% E-Value: 7.84e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (14%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 31% E-Value: 8.11e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_2785 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 31% E-Value: 8.11e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

slr2104 (15%) - slr1305 (18%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 28% E-Value: 7.33e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (18%) - slr2104 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 28% E-Value: 7.33e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1905 (15%) - slr1305 (18%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 4.75e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (18%) - sll1905 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 4.75e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

pilR (16%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 4.16e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (17%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 4.16e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (15%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 2.88e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (17%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 2.88e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (14%) - MXAN_7396 (19%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 32% E-Value: 1.69e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (19%) - MXAN_2785 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 32% E-Value: 1.69e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

cheY (16%) - HP_0392 (15%) (Helicobacter pylori (Campylobacter pylori))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 2.52e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Rain JC et al. (2001)

HP_0392 (15%) - cheY (16%) (Helicobacter pylori (Campylobacter pylori))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 2.52e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Rain JC et al. (2001)

slr1760 (16%) - slr1759 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 29% E-Value: 4.45e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (15%) - slr1760 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 29% E-Value: 4.45e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcB (16%) - hnr (14%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 1.13e-09

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

arcB (16%) - cheY (15%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 4.45e-10

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

cheY (15%) - arcB (16%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 4.45e-10

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

hnr (14%) - arcB (16%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 1.13e-09

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

asgD (17%) - MXAN_7143 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 1.58e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (14%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 1.58e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

nla28 (14%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 1.38e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (17%) - nla28 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 1.38e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (15%) - MXAN_7143 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 5.81e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (14%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 5.81e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (14%) - asgD (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 29% E-Value: 6.22e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (14%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 2.28e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (17%) - MXAN_2785 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 29% E-Value: 6.22e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (15%) - MXAN_2785 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 2.28e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (15%) - MXAN_2785 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 5.44e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (14%) - MXAN_7363 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 5.44e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1594 (14%) - slr1759 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 28% E-Value: 2.98e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1594 (14%) - slr1594 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 28% E-Value: 1.03e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (15%) - slr1594 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 28% E-Value: 2.98e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_2785 (14%) - MXAN_2785 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 28% E-Value: 4.92e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fixJ (12%) - fixJ (12%) (Rhizobium meliloti (Sinorhizobium meliloti))

Geometric mean of BLAST Identity: 12% Positives: 23% E-Value: 6.01e-07

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Gouet P et al. (1999)

glnG (12%) - glnG (12%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 24% E-Value: 6.42e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Salinas P et al. (2003)

Domain-Domain Interactions (3)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Trans_reg_C
structural domain contact	3DID	predicted interaction	Trans_reg_C	Trans_reg_C

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