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The Microbial Protein Interaction Database

Interaction Evidences

yedW - yedW ( Escherichia coli (strain K12) )

Protein A	Protein B
P76340 Probable transcriptional regulatory protein yedW yedW b1969, JW5322	P76340 Probable transcriptional regulatory protein yedW yedW b1969, JW5322
CMR Search...	CMR Search...
GO MF: protein binding GO MF: DNA binding GO MF: two-component response regulator activity GO CC: cytoplasm GO BP: sensory perception GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: protein binding GO MF: DNA binding GO MF: two-component response regulator activity GO CC: cytoplasm GO BP: sensory perception GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (163)

Experiments (1)

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

Interologs (159)

cusR (51%) - yedW (100%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 71% Positives: 86% E-Value: 6.96e-93

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

yedW (100%) - cusR (51%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 71% Positives: 86% E-Value: 6.96e-93

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (51%) - cusR (51%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 51% Positives: 74% E-Value: 6.36e-62

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_3450 (39%) - MXAN_3450 (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 39% Positives: 59% E-Value: 3.18e-37

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cpxR (38%) - cpxR (38%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 38% Positives: 55% E-Value: 5.25e-32

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_5313 (39%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 38% Positives: 53% E-Value: 2.06e-32

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (36%) - MXAN_5313 (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 38% Positives: 53% E-Value: 2.06e-32

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoB (36%) - phoB (36%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 36% Positives: 55% E-Value: 8.95e-32

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoP2 (36%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 36% Positives: 51% E-Value: 1.21e-28

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0797 (35%) - sll0797 (35%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 35% Positives: 53% E-Value: 6.64e-27

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

phoP (35%) - phoP (35%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 35% Positives: 56% E-Value: 1.53e-31

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

qseB (35%) - qseB (35%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 35% Positives: 56% E-Value: 1.17e-31

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_1680 (31%) - MXAN_3450 (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 55% E-Value: 4.44e-31

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (39%) - MXAN_1680 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 55% E-Value: 4.44e-31

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoB (36%) - ompR (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 34% Positives: 56% E-Value: 1.43e-29

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (33%) - phoB (36%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 34% Positives: 56% E-Value: 1.43e-29

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

rstA (34%) - rstA (34%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 34% Positives: 53% E-Value: 1.34e-27

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_5212 (30%) - MXAN_3450 (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 34% Positives: 55% E-Value: 3.40e-31

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (39%) - MXAN_5212 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 34% Positives: 55% E-Value: 3.40e-31

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (34%) - MXAN_4164 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 34% Positives: 55% E-Value: 5.08e-27

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

ompR (33%) - ompR (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 57% E-Value: 2.28e-27

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

creB (33%) - creB (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 50% E-Value: 5.26e-24

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpE (32%) - creB (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 52% E-Value: 7.34e-26

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

creB (33%) - kdpE (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 52% E-Value: 7.34e-26

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

rstA (34%) - kdpE (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 53% E-Value: 1.17e-27

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpE (32%) - rstA (34%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 53% E-Value: 1.17e-27

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

arcA (32%) - arcA (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 32% Positives: 49% E-Value: 3.41e-23

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_3450 (39%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 32% Positives: 48% E-Value: 4.75e-29

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (27%) - MXAN_3450 (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 32% Positives: 48% E-Value: 4.75e-29

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4164 (34%) - MXAN_1680 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 32% Positives: 53% E-Value: 5.62e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (31%) - MXAN_4164 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 32% Positives: 53% E-Value: 5.62e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

torR (31%) - torR (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 31% Positives: 49% E-Value: 6.87e-24

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2606 (27%) - MXAN_5995 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 45% E-Value: 1.21e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (35%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 45% E-Value: 1.21e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (36%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 44% E-Value: 9.27e-25

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (27%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 44% E-Value: 9.27e-25

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

baeR (30%) - baeR (30%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 30% Positives: 50% E-Value: 1.87e-21

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_1349 (35%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 47% E-Value: 3.41e-27

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (27%) - MXAN_1349 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 47% E-Value: 3.41e-27

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (34%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 46% E-Value: 6.01e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (27%) - MXAN_4164 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 46% E-Value: 6.01e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP (28%) - phoP (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 28% Positives: 57% E-Value: 2.98e-27

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)
molecular sieving		physical association	Bachhawat P et al. (2007)
x-ray crystallography		physical association	Bachhawat P et al. (2007)

MXAN_3450 (39%) - MXAN_7396 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 47% E-Value: 9.27e-25

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (20%) - MXAN_3450 (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 47% E-Value: 9.27e-25

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (27%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 39% E-Value: 7.11e-21

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (36%) - MXAN_7396 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 44% E-Value: 1.81e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (20%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 44% E-Value: 1.81e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (34%) - MXAN_7396 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 45% E-Value: 1.17e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (20%) - MXAN_4164 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 45% E-Value: 1.17e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (39%) - pilR (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 39% E-Value: 9.60e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (17%) - MXAN_5313 (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 39% E-Value: 9.60e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (17%) - MXAN_3450 (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 40% E-Value: 2.89e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (39%) - pilR (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 40% E-Value: 2.89e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5212 (30%) - MXAN_7396 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 44% E-Value: 9.93e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (20%) - MXAN_5212 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 44% E-Value: 9.93e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (39%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 41% E-Value: 4.45e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (39%) - MXAN_7363 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 38% E-Value: 3.77e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (15%) - MXAN_5313 (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 38% E-Value: 3.77e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (15%) - MXAN_5313 (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 41% E-Value: 4.45e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP3 (36%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 37% E-Value: 4.31e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (16%) - phoP3 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 37% E-Value: 4.31e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (36%) - MXAN_7143 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 36% E-Value: 1.10e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (36%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 37% E-Value: 7.60e-19

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7143 (15%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 36% E-Value: 1.10e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (16%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 37% E-Value: 7.60e-19

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilR (17%) - MXAN_5995 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 38% E-Value: 7.36e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (35%) - pilR (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 38% E-Value: 7.36e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (15%) - MXAN_3450 (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 38% E-Value: 1.69e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (15%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 35% E-Value: 3.30e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (39%) - MXAN_5853 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 38% E-Value: 1.69e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (36%) - MXAN_5853 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 35% E-Value: 3.30e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (20%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 38% E-Value: 1.39e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (27%) - MXAN_7396 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 38% E-Value: 1.39e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (31%) - pilR (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 37% E-Value: 4.04e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (17%) - MXAN_1680 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 37% E-Value: 4.04e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (15%) - MXAN_5995 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 40% E-Value: 3.41e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (35%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 40% E-Value: 3.41e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (36%) - MXAN_6149 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 2.80e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (13%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 2.80e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (12%) - MXAN_3450 (39%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 39% E-Value: 9.92e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (39%) - MXAN_2785 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 39% E-Value: 9.92e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (27%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 32% E-Value: 5.83e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (16%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 32% E-Value: 5.83e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (17%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 32% E-Value: 4.32e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (27%) - pilR (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 32% E-Value: 4.32e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (12%) - MXAN_5995 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 37% E-Value: 2.53e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (35%) - MXAN_2785 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 37% E-Value: 2.53e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1905 (23%) - slr1305 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 7.37e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (17%) - sll1905 (23%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 7.37e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_4645 (15%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 34% E-Value: 2.00e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (27%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 34% E-Value: 2.00e-15

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7363 (15%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 32% E-Value: 1.70e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (27%) - MXAN_7363 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 32% E-Value: 1.70e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (34%) - MXAN_2785 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 38% E-Value: 1.25e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (12%) - MXAN_4164 (34%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 38% E-Value: 1.25e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (15%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 31% E-Value: 2.53e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (27%) - MXAN_5853 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 31% E-Value: 2.53e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

TP_0519 (19%) - TP_0519 (19%) (Treponema pallidum)

Geometric mean of BLAST Identity: 19% Positives: 32% E-Value: 1.70e-14

Method

DB Source

Type

Publication

two hybrid array

physical association

Titz B et al. (2008)

cheB1 (13%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 5.64e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (27%) - cheB1 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 5.64e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (13%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 2.14e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (27%) - MXAN_6149 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 2.14e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr2100 (19%) - slr2098 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 1.81e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2098 (17%) - slr2100 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 18% Positives: 28% E-Value: 1.81e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_7396 (20%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 1.14e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (16%) - MXAN_7396 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 1.14e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (17%) - MXAN_7396 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 8.43e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (20%) - pilR (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 8.43e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (12%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 1.48e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (27%) - MXAN_2785 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 32% E-Value: 1.48e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

slr2104 (18%) - slr1305 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 32% E-Value: 1.22e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (17%) - slr2104 (18%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 32% E-Value: 1.22e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1760 (17%) - slr1759 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 31% E-Value: 4.94e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (17%) - slr1760 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 31% E-Value: 4.94e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

glnG (17%) - glnG (17%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 17% Positives: 30% E-Value: 1.64e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Salinas P et al. (2003)

MXAN_4645 (15%) - MXAN_7396 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 34% E-Value: 3.91e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (20%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 34% E-Value: 3.91e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sll1228 (15%) - sll1229 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 3.31e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1229 (17%) - sll1228 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 3.31e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1594 (16%) - slr1759 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 28% E-Value: 3.91e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1594 (16%) - slr1594 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 8.71e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (17%) - slr1594 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 28% E-Value: 3.91e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

cheB1 (13%) - MXAN_7396 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 30% E-Value: 1.10e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (20%) - cheB1 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 30% E-Value: 1.10e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (13%) - MXAN_7396 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 31% E-Value: 4.18e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (20%) - MXAN_6149 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 31% E-Value: 4.18e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (17%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 3.54e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (16%) - pilR (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 3.54e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

arcB (16%) - hnr (15%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 6.04e-08

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

arcB (16%) - cheY (15%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 2.71e-08

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

cheY (15%) - arcB (16%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 2.71e-08

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

hnr (15%) - arcB (16%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 6.04e-08

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

asgD (16%) - MXAN_7143 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 6.90e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (15%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 6.90e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

nla28 (14%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 4.62e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (16%) - nla28 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 4.62e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (13%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.76e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (16%) - MXAN_6149 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.76e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (15%) - MXAN_7143 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 2.37e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (15%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 1.64e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (15%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 2.37e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (16%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 1.64e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (12%) - MXAN_7396 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 31% E-Value: 2.90e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (20%) - MXAN_2785 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 31% E-Value: 2.90e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

cheY (13%) - HP_0392 (15%) (Helicobacter pylori (Campylobacter pylori))

Geometric mean of BLAST Identity: 14% Positives: 27% E-Value: 1.22e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Rain JC et al. (2001)

HP_0392 (15%) - cheY (13%) (Helicobacter pylori (Campylobacter pylori))

Geometric mean of BLAST Identity: 14% Positives: 27% E-Value: 1.22e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Rain JC et al. (2001)

slr2024 (14%) - slr2024 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 5.84e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

cheB1 (13%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 4.62e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (16%) - cheB1 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 4.62e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (14%) - MXAN_0460 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 4.47e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (12%) - asgD (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 1.22e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (12%) - MXAN_4645 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 28% E-Value: 4.18e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (16%) - MXAN_2785 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 1.22e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (15%) - MXAN_2785 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 28% E-Value: 4.18e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (15%) - MXAN_2785 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 3.54e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (12%) - MXAN_7363 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 3.54e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (15%) - MXAN_6149 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 7.63e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6149 (13%) - MXAN_5853 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 7.63e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (12%) - MXAN_2785 (12%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 26% E-Value: 3.10e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (3)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Trans_reg_C
structural domain contact	3DID	predicted interaction	Trans_reg_C	Trans_reg_C

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