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The Microbial Protein Interaction Database

Interaction Evidences

ompR - ompR ( Escherichia coli (strain K12) )

Protein A	Protein B
P0AA16 Transcriptional regulatory protein ompR ompR b3405, JW3368	P0AA16 Transcriptional regulatory protein ompR ompR b3405, JW3368
CMR Search...	CMR Search...
GO MF: protein binding GO MF: DNA binding GO MF: two-component response regulator activity GO CC: cytoplasm GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: protein binding GO MF: DNA binding GO MF: two-component response regulator activity GO CC: cytoplasm GO BP: transcription GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (156)

Experiments (1)

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

Interologs (152)

phoB (36%) - ompR (100%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 60% Positives: 74% E-Value: 2.65e-85

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (100%) - phoB (36%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 60% Positives: 74% E-Value: 2.65e-85

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cpxR (40%) - cpxR (40%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 40% Positives: 60% E-Value: 7.56e-40

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_5313 (41%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 39% Positives: 58% E-Value: 1.57e-41

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (36%) - MXAN_5313 (41%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 39% Positives: 58% E-Value: 1.57e-41

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP (38%) - phoP (38%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 38% Positives: 57% E-Value: 1.80e-41

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

baeR (37%) - baeR (37%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 37% Positives: 59% E-Value: 9.24e-38

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (36%) - phoB (36%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 36% Positives: 55% E-Value: 1.74e-36

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

arcA (36%) - arcA (36%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 36% Positives: 55% E-Value: 5.07e-36

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (36%) - cusR (36%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 36% Positives: 54% E-Value: 1.38e-33

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoP2 (36%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 36% Positives: 55% E-Value: 9.24e-38

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (35%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 35% Positives: 56% E-Value: 2.35e-33

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

torR (33%) - torR (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 55% E-Value: 4.74e-34

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoP (33%) - phoP (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 56% E-Value: 3.18e-30

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)
molecular sieving		physical association	Bachhawat P et al. (2007)
x-ray crystallography		physical association	Bachhawat P et al. (2007)

rstA (33%) - kdpE (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 55% E-Value: 2.52e-31

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpE (32%) - rstA (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 55% E-Value: 2.52e-31

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

rstA (33%) - rstA (33%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 56% E-Value: 2.35e-33

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (36%) - yedW (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 53% E-Value: 1.87e-30

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

yedW (31%) - cusR (36%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 33% Positives: 53% E-Value: 1.87e-30

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

creB (32%) - creB (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 32% Positives: 49% E-Value: 3.18e-30

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

kdpE (32%) - creB (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 32% Positives: 51% E-Value: 9.26e-30

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

creB (32%) - kdpE (32%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 32% Positives: 51% E-Value: 9.26e-30

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

sll0797 (31%) - sll0797 (31%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 31% Positives: 52% E-Value: 1.25e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

yedW (31%) - yedW (31%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 31% Positives: 53% E-Value: 2.52e-27

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_3450 (31%) - MXAN_3450 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 49% E-Value: 1.25e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5212 (31%) - MXAN_3450 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 51% E-Value: 1.69e-27

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (31%) - MXAN_5212 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 31% Positives: 51% E-Value: 1.69e-27

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

qseB (30%) - qseB (30%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 30% Positives: 48% E-Value: 6.87e-25

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_4164 (35%) - MXAN_1680 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 48% E-Value: 1.63e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (26%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 48% E-Value: 1.63e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_5995 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 42% E-Value: 1.10e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (36%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 42% E-Value: 1.10e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (26%) - MXAN_3450 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 44% E-Value: 3.77e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (31%) - MXAN_1680 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 44% E-Value: 3.77e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (22%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 43% E-Value: 2.00e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (36%) - MXAN_5853 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 43% E-Value: 2.00e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (36%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 43% E-Value: 1.69e-27

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 43% E-Value: 1.69e-27

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1349 (36%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 43% E-Value: 7.58e-28

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_1349 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 43% E-Value: 7.58e-28

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (35%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 44% E-Value: 2.70e-25

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 44% E-Value: 2.70e-25

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (41%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 41% E-Value: 8.10e-30

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (17%) - MXAN_5313 (41%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 41% E-Value: 8.10e-30

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (41%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 40% E-Value: 1.81e-29

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (16%) - MXAN_5313 (41%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 40% E-Value: 1.81e-29

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (22%) - MXAN_3450 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 41% E-Value: 7.35e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (31%) - MXAN_5853 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 26% Positives: 41% E-Value: 7.35e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (31%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 41% E-Value: 6.22e-22

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_3450 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 41% E-Value: 6.22e-22

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (36%) - MXAN_7396 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 40% E-Value: 4.76e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (18%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 40% E-Value: 4.76e-26

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (17%) - MXAN_5995 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 38% E-Value: 3.09e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (36%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 38% E-Value: 3.09e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (35%) - MXAN_7396 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 40% E-Value: 7.59e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (18%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 40% E-Value: 7.59e-24

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (16%) - MXAN_5995 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 37% E-Value: 6.88e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (36%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 37% E-Value: 6.88e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (16%) - MXAN_5995 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 36% E-Value: 3.30e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (36%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 36% E-Value: 3.30e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (35%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 38% E-Value: 8.12e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (16%) - MXAN_4164 (35%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 24% Positives: 38% E-Value: 8.12e-22

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll0649 (40%) - sll1592 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 23% Positives: 38% E-Value: 1.69e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1592 (13%) - sll0649 (40%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 23% Positives: 38% E-Value: 1.69e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_3450 (31%) - MXAN_7396 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 38% E-Value: 1.75e-20

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (18%) - MXAN_3450 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 38% E-Value: 1.75e-20

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (36%) - asgD (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 37% E-Value: 8.68e-24

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (14%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 37% E-Value: 8.68e-24

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_5212 (31%) - MXAN_7396 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 39% E-Value: 2.36e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (18%) - MXAN_5212 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 39% E-Value: 2.36e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (36%) - MXAN_7143 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 3.30e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (14%) - phoP2 (36%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 3.30e-23

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (16%) - MXAN_3450 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 3.90e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (31%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 36% E-Value: 3.90e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (16%) - MXAN_3450 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 35% E-Value: 1.87e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (31%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 35% E-Value: 1.87e-18

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7024 (16%) - MXAN_5212 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 38% E-Value: 3.30e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5212 (31%) - MXAN_7024 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 38% E-Value: 3.30e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (22%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 34% E-Value: 3.65e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_5853 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 34% E-Value: 3.65e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 34% E-Value: 3.09e-17

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP3 (32%) - asgD (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 36% E-Value: 7.35e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (14%) - phoP3 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 36% E-Value: 7.35e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1680 (26%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 33% E-Value: 1.17e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (16%) - MXAN_1680 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 33% E-Value: 1.17e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

sll1228 (22%) - sll1229 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 19% Positives: 30% E-Value: 3.09e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1229 (16%) - sll1228 (22%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 19% Positives: 30% E-Value: 3.09e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2100 (19%) - slr2098 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 19% Positives: 30% E-Value: 4.94e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2098 (20%) - slr2100 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 19% Positives: 30% E-Value: 4.94e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_7396 (18%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 8.70e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_7396 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 8.70e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (17%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 30% E-Value: 1.49e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - cheB1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 30% E-Value: 1.49e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (17%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 8.70e-16

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 31% E-Value: 8.70e-16

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sll1905 (19%) - slr1305 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 6.66e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (17%) - sll1905 (19%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 6.66e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

frzS (15%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 1.30e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - frzS (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 1.30e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilR (16%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 1.94e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (21%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 1.94e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (16%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 29% E-Value: 9.30e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 29% E-Value: 9.30e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

frzZ (14%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622) - Myxococcus xanthus)

Geometric mean of BLAST Identity: 17% Positives: 29% E-Value: 4.04e-13

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - frzZ (14%) (Myxococcus xanthus (strain DK 1622) - Myxococcus xanthus)

Geometric mean of BLAST Identity: 17% Positives: 29% E-Value: 4.04e-13

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (21%) - asgD (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 29% E-Value: 1.59e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (14%) - MXAN_2606 (21%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 29% E-Value: 1.59e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (17%) - MXAN_7396 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 4.18e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (18%) - cheB1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 4.18e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (16%) - MXAN_7396 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 5.45e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (18%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 5.45e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (17%) - MXAN_7396 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 2.45e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (18%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 2.45e-14

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (16%) - MXAN_7396 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 2.62e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (16%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 2.62e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (18%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 2.62e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4645 (17%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 2.62e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1760 (16%) - slr1759 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 28% E-Value: 1.88e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (16%) - slr1760 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 28% E-Value: 1.88e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_7396 (18%) - asgD (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 4.47e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (14%) - MXAN_7396 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 4.47e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (17%) - asgD (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 4.47e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (14%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 4.47e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (16%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 2.80e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB (15%) - cheY (16%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 3.91e-08

Method	DB Source	Type	Publication
unspecified method		physical association	Ninfa EG et al. (1991)

cheY (16%) - cheB (15%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 3.91e-08

Method	DB Source	Type	Publication
unspecified method		physical association	Ninfa EG et al. (1991)

slr2104 (13%) - slr1305 (17%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 8.71e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (17%) - slr2104 (13%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 8.71e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

glnG (15%) - glnG (15%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 29% E-Value: 3.54e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Salinas P et al. (2003)

cheB1 (17%) - asgD (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 7.63e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (14%) - cheB1 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 7.63e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

nla28 (15%) - asgD (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 4.78e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (14%) - nla28 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 4.78e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (15%) - frzZ (14%) (Myxococcus xanthus - Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 1.88e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0460 (15%) - MXAN_0460 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 6.67e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

frzZ (14%) - MXAN_0460 (15%) (Myxococcus xanthus - Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 1.88e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (16%) - asgD (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 9.95e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (14%) - pilR (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 9.95e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (17%) - MXAN_7143 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.70e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (14%) - MXAN_4645 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.70e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (16%) - asgD (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 4.78e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (14%) - MXAN_2785 (16%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 4.78e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheY (15%) - HP_0392 (13%) (Helicobacter pylori (Campylobacter pylori))

Geometric mean of BLAST Identity: 14% Positives: 28% E-Value: 4.18e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Rain JC et al. (2001)

HP_0392 (13%) - cheY (15%) (Helicobacter pylori (Campylobacter pylori))

Geometric mean of BLAST Identity: 14% Positives: 28% E-Value: 4.18e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Rain JC et al. (2001)

slr1594 (12%) - slr1759 (16%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 29% E-Value: 9.96e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (16%) - slr1594 (12%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 29% E-Value: 9.96e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2024 (14%) - slr2024 (14%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 27% E-Value: 2.62e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

asgD (14%) - MXAN_7143 (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 3.10e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7143 (14%) - asgD (14%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 3.10e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

fixJ (13%) - fixJ (13%) (Rhizobium meliloti (Sinorhizobium meliloti))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 3.42e-08

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Gouet P et al. (1999)

TP_0519 (12%) - TP_0519 (12%) (Treponema pallidum)

Geometric mean of BLAST Identity: 12% Positives: 25% E-Value: 2.01e-08

Method

DB Source

Type

Publication

two hybrid array

physical association

Titz B et al. (2008)

slr1594 (12%) - slr1594 (12%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 26% E-Value: 7.14e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

Domain-Domain Interactions (3)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Trans_reg_C
structural domain contact	3DID	predicted interaction	Trans_reg_C	Trans_reg_C

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