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The Microbial Protein Interaction Database

Interaction Evidences

Cj1227c - A3ZCK1 ( Campylobacter jejuni-Campylobacter jejuni subsp jejuni HB93-13)

Protein A	Protein B
Q0P929 Putative two-component regulator Cj1227c	A3ZCK1 Sensor kinase of two-component regulatory system
CMR Search...	CMR Search...
GO MF: DNA binding GO MF: two-component response regulator activity GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...	GO MF: two-component sensor activity GO MF: ATP binding GO BP: signal transduction GO BP: peptidyl-histidine phosphorylation

List of evidences (63)

Experiments (1)

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Svensson SL et al. (2009)

Interologs (62)

MXAN_4164 (34%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 30% Positives: 51% E-Value: 2.32e-20

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (32%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 29% Positives: 51% E-Value: 2.93e-19

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (37%) - pilS (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 29% Positives: 51% E-Value: 1.40e-21

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (29%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 28% Positives: 49% E-Value: 1.04e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_3450 (28%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 49% E-Value: 3.95e-16

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (28%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 27% Positives: 49% E-Value: 8.81e-16

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

cpxR (34%) - cpxA (20%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 26% Positives: 49% E-Value: 1.08e-17

Method	DB Source	Type	Publication
unspecified method		physical association	Nakayama S et al. (2003)

MXAN_3450 (28%) - pilS (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 46% E-Value: 9.42e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (28%) - pilS (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 25% Positives: 46% E-Value: 2.10e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (19%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 42% E-Value: 2.03e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5212 (29%) - MXAN_3606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 39% E-Value: 7.46e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (34%) - MXAN_7206 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 37% E-Value: 1.61e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (27%) - MXAN_2606 (18%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 38% E-Value: 1.19e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1680 (20%) - MXAN_1350 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 22% Positives: 41% E-Value: 5.17e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

rcp1 (18%) - cph1 (25%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 21% Positives: 37% E-Value: 3.96e-08

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Yeh KC et al. (1997)
protein kinase assay		phosphorylation	Lamparter T et al. (2001)

slr1909 (17%) - sll1003 (26%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 21% Positives: 37% E-Value: 1.41e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_7396 (19%) - pilS (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 40% E-Value: 4.84e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_3450 (28%) - MXAN_7206 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 35% E-Value: 2.74e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (18%) - MXAN_1350 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 39% E-Value: 3.71e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (28%) - MXAN_7206 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 35% E-Value: 6.11e-13

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1680 (20%) - pilS (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 38% E-Value: 3.96e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (16%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 36% E-Value: 2.25e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4164 (34%) - MXAN_6688 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 37% E-Value: 2.74e-17

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (16%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 21% Positives: 38% E-Value: 3.24e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

sll1229 (15%) - sll1228 (25%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 20% Positives: 36% E-Value: 1.78e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_5995 (29%) - MXAN_6688 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 1.23e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (14%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 36% E-Value: 1.41e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (15%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 7.22e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (18%) - pilS (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 36% E-Value: 2.84e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilR (14%) - MXAN_2606 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 35% E-Value: 2.10e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (16%) - MXAN_1350 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 37% E-Value: 6.99e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (32%) - MXAN_6688 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 37% E-Value: 3.46e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (29%) - MXAN_0459 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 20% Positives: 34% E-Value: 2.17e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1037 (16%) - slr1393 (23%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 19% Positives: 34% E-Value: 9.13e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

zraR (14%) - zraS (27%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 19% Positives: 38% E-Value: 4.38e-11

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)

pleD (18%) - pleC (21%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 19% Positives: 38% E-Value: 1.78e-08

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

cheB1 (15%) - MXAN_1350 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 35% E-Value: 2.25e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (28%) - MXAN_6688 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 35% E-Value: 1.04e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pilR (14%) - MXAN_1350 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 19% Positives: 36% E-Value: 6.54e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1594 (13%) - sasA (25%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 18% Positives: 37% E-Value: 5.72e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1291 (13%) - sasA (25%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 18% Positives: 35% E-Value: 2.94e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

hnr (14%) - arcB (24%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 18% Positives: 33% E-Value: 2.66e-08

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

asgD (14%) - pilS (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 34% E-Value: 3.36e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilR (14%) - pilS (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 34% E-Value: 5.01e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (18%) - MXAN_3606 (17%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 18% Positives: 30% E-Value: 1.41e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (19%) - MXAN_7206 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 30% E-Value: 1.41e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (18%) - MXAN_7206 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 28% E-Value: 8.25e-10

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_1680 (20%) - MXAN_7206 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 29% E-Value: 1.15e-11

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4164 (34%) - MXAN_4165 (9%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 17% Positives: 30% E-Value: 4.67e-17

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

slr1909 (17%) - slr0210 (15%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 28% E-Value: 2.74e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

glnG (12%) - glnL (22%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 16% Positives: 32% E-Value: 5.18e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Salinas P et al. (2003)

MXAN_7396 (19%) - MXAN_6688 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 30% E-Value: 2.40e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (18%) - MXAN_7142 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 16% Positives: 29% E-Value: 5.53e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (18%) - MXAN_6688 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 1.41e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

cheB1 (15%) - MXAN_7206 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 25% E-Value: 5.01e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

pilR (14%) - MXAN_7206 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.46e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (16%) - MXAN_7206 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.56e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (16%) - MXAN_7206 (15%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 2.25e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (14%) - MXAN_6688 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 1.67e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (15%) - MXAN_6688 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 25% E-Value: 8.54e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (16%) - MXAN_6688 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 28% E-Value: 3.83e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5853 (16%) - MXAN_0459 (13%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 27% E-Value: 6.76e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

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