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The Microbial Protein Interaction Database

Interaction Evidences

cph1 - rcp1 ( Synechocystis sp (strain PCC 6803) )

Protein A	Protein B
Q55168 Phytochrome-like protein cph1 cph1 slr0473	Q55169 Response regulator rcp1 rcp1 slr0474
CMR Search...	CMR Search...
GO MF: identical protein binding GO MF: G-protein coupled photoreceptor activity GO MF: ATP binding GO MF: two-component sensor activity GO MF: red or far-red light photoreceptor activity GO CC: membrane GO BP: regulation of transcription, DNA-dependent GO BP: peptidyl-histidine phosphorylation GO BP: protein-chromophore linkage GO BP: response to red or far red light GO BP: signal transduction GO BP: red, far-red light phototransduction GO BP: protein amino acid autophosphorylation	GO MF: protein binding GO MF: two-component response regulator activity GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (43)

Experiments (2)

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Yeh KC et al. (1997)
protein kinase assay		phosphorylation	Lamparter T et al. (2001)

Interologs (40)

slr1393 (10%) - slr1037 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 17% Positives: 27% E-Value: 2.01e-15

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

pleC (10%) - pleD (27%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 17% Positives: 29% E-Value: 2.71e-16

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

sll1228 (11%) - sll1229 (24%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 27% E-Value: 9.63e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sasA (10%) - sll1291 (26%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 28% E-Value: 7.14e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr0533 (9%) - sll0649 (27%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 25% E-Value: 1.82e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2098 (9%) - slr2100 (27%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 16% Positives: 26% E-Value: 9.63e-14

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1759 (11%) - slr1594 (21%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 29% E-Value: 5.11e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1905 (11%) - slr1305 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 5.46e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1353 (9%) - sll1905 (25%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 4.18e-13

Method

DB Source

Type

Publication

two hybrid

physical association

Sato S et al. (2007)

yycG (9%) - yycF (25%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 4.94e-14

Method	DB Source	Type	Publication
enzymatic study		physical association	Fukuchi K et al. (2000)

kdpD (9%) - kdpE (26%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 3.79e-10

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Luttmann D et al. (2009)
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)
enzymatic study		physical association	Heermann R et al. (2003)
protein kinase assay		physical association	Luttmann D et al. (2009)

pleC (10%) - divK (23%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 1.81e-16

Method

DB Source

Type

Publication

dephosphorylation

phosphorylation

divJ (8%) - pleD (27%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 4.18e-13

Method	DB Source	Type	Publication
protein kinase assay		phosphorylation	Paul R et al. (2008)

MXAN_2606 (9%) - MXAN_5995 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 28% E-Value: 2.62e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_1349 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 27% E-Value: 4.48e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (9%) - MXAN_5995 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.88e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (9%) - MXAN_5995 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 15% Positives: 26% E-Value: 1.65e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cpxA (7%) - cpxR (27%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 4.33e-10

Method	DB Source	Type	Publication
unspecified method		physical association	Nakayama S et al. (2003)

sasA (10%) - slr1594 (21%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 14% Positives: 27% E-Value: 5.46e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

pleC (10%) - divK (19%) (Brucella abortus - Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 9.01e-16

Method	DB Source	Type	Publication
two hybrid		physical association	Hallez R et al. (2007)

phoR1 (8%) - MXAN_1349 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 2.62e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (9%) - MXAN_4072 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 28% E-Value: 9.97e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (9%) - MXAN_4072 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 7.14e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_0459 (9%) - MXAN_4072 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 6.25e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR1 (8%) - phoP1 (22%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 14% Positives: 26% E-Value: 1.18e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

A3ZCK1 (7%) - Cj1227c (27%) (Campylobacter jejuni - Campylobacter jejuni subsp jejuni HB93-13)

Geometric mean of BLAST Identity: 14% Positives: 24% E-Value: 6.05e-08

Method	DB Source	Type	Publication
adenylate cyclase complementation		physical association	Svensson SL et al. (2009)

BruAb1_0598 (8%) - divK (19%) (Brucella abortus)

Geometric mean of BLAST Identity: 13% Positives: 24% E-Value: 9.02e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Hallez R et al. (2007)

sll1003 (9%) - slr1909 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 25% E-Value: 3.79e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sphS (8%) - slr1594 (21%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 27% E-Value: 1.82e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2104 (9%) - slr1305 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 13% Positives: 26% E-Value: 1.07e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

divJ (8%) - divK (23%) (Caulobacter crescentus (Caulobacter vibrioides))

Geometric mean of BLAST Identity: 13% Positives: 26% E-Value: 2.80e-13

Method

DB Source

Type

Publication

protein kinase assay

phosphorylation

Paul R et al. (2008)

MXAN_7398 (8%) - MXAN_4072 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 26% E-Value: 3.66e-13

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoR2 (9%) - MXAN_4072 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 26% E-Value: 6.25e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

pdhS (7%) - divK (19%) (Brucella abortus)

Geometric mean of BLAST Identity: 12% Positives: 24% E-Value: 2.37e-12

Method

DB Source

Type

Publication

two hybrid

physical association

Hallez R et al. (2007)

slr0210 (7%) - slr1909 (20%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 24% E-Value: 1.03e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

MXAN_3451 (8%) - MXAN_4072 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 26% E-Value: 7.90e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_5995 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 1.35e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_1349 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 2.30e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7206 (6%) - MXAN_4072 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 22% E-Value: 6.69e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_6688 (5%) - MXAN_4072 (20%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 21% E-Value: 5.12e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (1)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID	predicted interaction	Response_reg	HisKA

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