Nicholas J. Schork, PhD

Director of Human Biology



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Nicholas J. Schork, PhD is a professor and director of human biology at the J. Craig Venter Institute. Dr. Schork’s research focuses on the quantitative aspects of human biomedical research, including computational biology, bioinformatics and biostatistics. He has a particular emphasis on translational research, including the design of data-intensive, assay-rich clinical intervention and monitoring studies. Dr. Schork is also a distinguished professor at the Translational Genomics Research Institute (TGen) in Phoenix, AZ as well as an adjunct professor at the University of California, San Diego (UCSD). Prior to joining JCVI, Dr. Schork held faculty positions at The Scripps Research Institute, UCSD, and Case Western Reserve University. Dr. Schork has published over 500 peer-reviewed research articles, mentored over 75 trainees, has been on 8 patents, has given over 250 invited lectures, and has been involved in over 15 different start-up companies or commercial ventures in the biomedical space. Dr. Schork is a graduate of the University of Michigan in Ann Arbor, Michigan.

Research Priorities

  1. Development, Implementation and Interpretation of data analysis methods for addressing human biomedical science problems
  2. Design of strategies for integrating different sources of information (e.g., different assay results) in biomedical studies
  3. Design of clinical studies, including clinical trials


Select Publications

Group-based variant calling leveraging next-generation supercomputing for large-scale whole-genome sequencing studies.
BMC bioinformatics. 2015-09-22; 16.304.
PMID: 26395405
Personalized medicine: Time for one-person trials.
Nature. 2015-04-30; 520.7549: 609-11.
PMID: 25925459
Clinical implications of human population differences in genome-wide rates of functional genotypes.
Frontiers in genetics. 2012-01-01; 3.211.
PMID: 23125845