Pamila Brar, MD

Chief Medical Officer
Adjunct Scientist

Dr. Pamila Brar is chief medical officer at the J. Craig Venter Institute. In this capacity, she oversees the clinical aspects of a novel research effort that combines the power of genomics, metabolomics and microbiome with electronic medical records and artificial intelligence to identify markers of health and disease. From 2015 to 2018, Dr. Brar served as Medical Director of the Health Nucleus at Human Longevity, Inc, a precision medicine research clinic. In that role, Dr. Brar led a multidisciplinary team responsible for the integration of whole genome sequencing, microbiome, metabolome and whole-body imaging, as well as the delivery of results to the participants.

Pam holds an MD degree from Louisiana State University at New Orleans. She is certified both by the American Board of Internal Medicine, and the American Board of Integrative Holistic Medicine. Dr. Brar is a graduate of the Scripps Clinic Internal Medicine Residency Program and was named the Ellen Browning Scripps Chief Medical Resident in 1998. She then joined the Division of Internal Medicine at Scripps Clinic where she practiced from 1999 to 2009. Pam then opened her own private concierge medicine practice in 2009 in La Jolla, CA. She served as President for the American Academy of Private Physicians from 2015 to 2017. Founded in 2003, the AAPP is a national non-profit organization that provides advocacy for the direct patient-doctor relationship and explores solutions to our changing health care system. Pam is a member of the board of directors of the Clearity Foundation, a non-profit which strives to improve the survival and quality of life for women with ovarian cancer.  Ultimately it was her love for science and innovation that led her to pivot from clinical practice to a precision-medicine based clinical research.

Building the Human Performance Center to explore the genetic and phenotypic underpinnings of human health and disease.
  • This initiative will leverage genomics, imaging and artificial intelligence to make associations between genotype and phenotype.
Characterization of Sleep Disorders.
  • Our team will examine the molecular basis for sleep apnea and other common sleep disorders by utilizing whole genome sequencing as well as physical measures of sleep. We believe that these learnings will greatly enhance the detection of otherwise underrecognized sleep disorders as well as provide a means of personalizing individual treatment.
Exploring Personality.
  • This project will explore the genetic and physical contributions to personality and resiliency. We believe that this will expand our understanding of one’s underlying temperament and provide information to guide decision making on an individual and team basis.

Publications

An unsupervised learning approach to identify novel signatures of health and disease from multimodal data.
Genome medicine. 2020-01-10; 12.1: 7.
PMID: 31924279
Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults.
Proceedings of the National Academy of Sciences of the United States of America. 2018-04-03; 115.14: 3686-3691.
PMID: 29555771
Human Performance Center