Tyler Coale, PhD

Post-Doctoral Fellow

Tyler Coale is a post-doctoral fellow with Andrew Allen at the J. Craig Venter Institute. Dr. Coale investigates the cellular functioning and ecology of eukaryotic marine phytoplankton. In the lab he uses reverse genetic techniques including fluorescent labeling and CRISPR-Cas9 gene editing to characterize protein function in model phytoplankton species. In the field he surveys the distribution and gene expression of natural phytoplankton communities and has participated in more than a dozen research cruises in the Pacific and Atlantic Oceans. Of particular interest are the adaptations of marine phytoplankton to the low iron conditions typical of the open ocean. These include acquisition proteins, intracellular trafficking, and strategies to improve iron use efficiency. Laboratory efforts include gene knockouts of specific iron-related genes, culturing phytoplankton under low iron conditions, and transcriptomic profiling of iron-starved algae. Findings from this work refine our understanding of global controls on marine phytoplankton distributions and ocean productivity.

Prior to employment at JCVI, Dr. Coale obtained a BS in Plant Sciences from the University of California, Santa Cruz. He worked in the chemical oceanography labs of Kenneth Bruland at UCSC and Kristen Buck at the Bermuda Institute of Ocean Sciences. In 2020 he received his PhD from Scripps Institution of Oceanography.

Iron acquisition in marine phytoplankton
  • Molecular mechanisms enabling siderophore acquisition
  • Iron uptake kinetics
  • Phytoplankton-bacteria interactions under low iron conditions
Adaptations of eukaryotic phytoplankton to trace metal availability
  • Transcriptome and proteome remodeling in response to iron limitation
  • Physiological changes related to iron bioavailability
  • Molecular indicators of iron stress in marine environments

Publications

Reduction-dependent siderophore assimilation in a model pennate diatom.
Proceedings of the National Academy of Sciences of the United States of America. 2019-11-19; 116.47: 23609-23617.
PMID: 31685631
Growth, fire history, and browsing recorded in wood rings of shrubs in a mild temperate climate.
Ecology. 2011-05-01; 92.5: 1020-6.
PMID: 21661563
Iron acquisition in marine phytoplankton
  • Molecular mechanisms enabling siderophore acquisition
  • Iron uptake kinetics
  • Phytoplankton-bacteria interactions under low iron conditions
Adaptations of eukaryotic phytoplankton to trace metal availability
  • Transcriptome and proteome remodeling in response to iron limitation
  • Physiological changes related to iron bioavailability
  • Molecular indicators of iron stress in marine environments