Vincent Bielinski, PhD

Staff Scientist

Vincent Bielinski is a staff scientist in the Synthetic Biology department at JCVI.  His primary research focus is enabling the design and implementation of novel genetic circuits for use in microorganisms. This work includes the isolation and domestication of native and synthetic genetic parts from across multiple species and in vivo analysis of circuit function.

Vincent received his PhD in Cell Regulation from UT Southwestern Medical Center at Dallas, as well as a Bachelor’s in Microbiology from the university of Oklahoma. He also spent several years working in the private algal biofuel and pharmaceutical sectors in San Diego at Sapphire Energy, Synthetic Genomics, and Dart Neuroscience prior to joining JCVI.

Patents

Bielinski, Vincent; Bauman, Nicholas; Boyd, Kate Lyons; Akella, Srividya; Bower, Stanley; Roessler, Paul. 2015.
Regulation of toxin and antitoxin genes for biological containment.
U.S. Patent 8,975,061, filed June 28, 2012, and issued March 10, 2015.

Research Priorities

Construction of genetic circuits
  • Part identification and registry
  • Developing molecular timers and kill switches
Advancing canonical model organisms
  • Diatoms, moss, soil bacteria
Metabolic Engineering of microorganisms
  • Renewable energy and fuels

Publications

Diatom centromeres suggest a mechanism for nuclear DNA acquisition.
Proceedings of the National Academy of Sciences of the United States of America. 2017-07-18; 114.29: E6015-E6024.
PMID: 28673987
Refinement of the Diatom Episome Maintenance Sequence and Improvement of Conjugation-Based DNA Delivery Methods.
Frontiers in bioengineering and biotechnology. 2016-01-01; 4.65.
PMID: 27551676
Functional analysis of the PP2A subfamily of protein phosphatases in regulating Drosophila S6 kinase.
Experimental cell research. 2007-08-15; 313.14: 3117-26.
PMID: 17570358

Research Priorities

Construction of genetic circuits
  • Part identification and registry
  • Developing molecular timers and kill switches
Advancing canonical model organisms
  • Diatoms, moss, soil bacteria
Metabolic Engineering of microorganisms
  • Renewable energy and fuels
27-Sep-2018
Press Release

Domoic Acid Decoded: Scientists Discover Genetic Basis for How Harmful Algal Blooms Become Toxic

Research into gene function in microalgae helps determine how toxins are made in oceanic harmful algal blooms