Yujia Li, PhD

Post-Doctoral Fellow


858-200-1899

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Bio

Yujia Li, PhD, joined the J. Craig Venter Institute at La Jolla, CA in 2018 as a post-doctoral fellow in the Synthetic Biology and Bioenergy Group. He is currently participating in assay development for identifying viral genes that interfere with the insect innate immune system.

Prior to joining JCVI, he was a post-doctoral associate in Dr. Griffith Parks’s lab at the University of Central Florida. During that time, Dr. Li was trying to address the questions of how RNA viruses, including parainfluenza virus 5 (PIV5) and Zika virus (ZIKV), first activate and then suppress important human complement immune pathways in order to successfully replicate.

Dr. Li received a BS in bioengineering and an MS in biochemistry and molecular biology from Northeast Forestry University in China, and a PhD in microbiology from University of Hawaii at Manoa.

Research Priorities

Establish a rapid test to identify viral genes that suppress insect innate immunity

  • Identify a non- or less permissive insect cell line for arbovirus
  • Introduce test viral genes to insect cells by yeast fusion
Zika virus as an oncolytic treatment of human neuroblastoma cells requires CD24.
PloS one. 2018-07-25; 13.7: e0200358.
PMID: 30044847
Relative Contribution of Cellular Complement Inhibitors CD59, CD46, and CD55 to Parainfluenza Virus 5 Inhibition of Complement-Mediated Neutralization.
Viruses. 2018-04-25; 10.5:
PMID: 29693588
Parainfluenza virus 5 upregulates CD55 expression to produce virions with enhanced resistance to complement-mediated neutralization.
Virology. 2016-10-01; 497.305-313.
PMID: 27505156
Human apolipoprotein A-I is associated with dengue virus and enhances virus infection through SR-BI.
PloS one. 2013-07-24; 8.7: e70390.
PMID: 23894648