Autoimmune Diseases

Autoimmune diseases are a family of over 80 chronic, disabling illnesses in which defects in the immune system leads the body to attack normal components (self-antigens) of its own tissues. Autoimmune diseases affect 14.7 – 23.5 million people in the U.S. alone (5 – 8%), making it one of the most common classes of human diseases. However, despite several decades of research being devoted to understanding autoimmunity, a coherent explanation of the critical causative events that initiate the autoimmune response is still lacking. JCVI is attacking this problem by applying cutting-edge genomics, bioinformatics and machine learning approaches to discover the causes of autoimmunity and develop novel therapeutic approaches to alleviate and cure these diseases.

Autoimmune Diseases

Autoimmune diseases are a family of over 80 chronic, disabling illnesses in which defects in the immune system leads the body to attack normal components (self-antigens) of its own tissues. Autoimmune diseases affect 14.7 – 23.5 million people in the U.S. alone (5 – 8%), making it one of the most common classes of human diseases. However, despite several decades of research being devoted to understanding autoimmunity, a coherent explanation of the critical causative events that initiate the autoimmune response is still lacking. JCVI is attacking this problem by applying cutting-edge genomics, bioinformatics and machine learning approaches to discover the causes of autoimmunity and develop novel therapeutic approaches to alleviate and cure these diseases.

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Key Staff

John Glass, PhD
Professor
Rembert Pieper, PhD
Director, Rockville Campus; Professor
Richard H. Scheuermann, PhD
Director, La Jolla Campus; Professor
Yo Suzuki, PhD
Assistant Professor

Archived Research Projects