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Scientists Decipher Genome of Biothreat Pathogen
Highly Regulated Virulence Genes and Genomic Instability Found in the Infectious Horse Pathogen Burkholderia mallei
16TH International Genome Sequencing and Analysis Conference Features NIAID Director Anthony Fauci, Biologist E.O. Wilson and other Eminent Scientists
Conference in Washington, DC, highlights cutting-edge work in environmental genomics, human genomic medicine, biological energy production, evolutionary biology, and new sequencing technologies
GSAC also hosts half-day policy session on biodiversity and intellectual property issues
Scientists Explore Genome of Methane-breathing Microbe
First Complete DNA Sequence of a Methanotroph Reveals Metabolic Flexibility, Suggests Mechanisms for Increasing Its Usefulness For Biotechnology
TIGR Scientists Explore Microbes on Shipwrecks and Coral
Researchers embarked on two separate expeditions this week to explore microbial communities on deep-sea corals in the Gulf of Alaska and on shipwrecks in the Gulf of Mexico.
Bioinformatics Resource Center at TIGR to Focus on Biothreat Pathogens
TIGR has signed a five-year, $21.1 million contract with the National Institute of Allergy and Infectious Diseases to establish and maintain a new national Bioinformatics Resource Center for the study of pathogens that are considered biothreat agents or are associated with emerging or re-emerging infectious diseases.
Anthrax Toxin Genes Found in Another Microbial Species
For the first time, researchers have found anthrax toxin genes in a naturally occurring microbe other than Bacillus anthracis, the bacterium that causes anthrax. The microbe that contains those anthrax genes is a strain of Bacillus cereus isolated from a patient with a medical condition similar to inhalation anthrax.
Decoding a Sulfate-Breathing Bug
Paving the way for better methods to protect pipelines and remediate metallic pollutants, TIGR scientists and collaborators have deciphered the genome of a sulfate-breathing bacterium, Desulfovibrio vulgaris, which can damage oil and natural gas pipelines and corrode oilfield equipment.
Scientists Decipher the Rat Genome
An international consortium of scientists that includes TIGR has completed a high-quality draft sequence of the rat genome. Comparing the rat to the human and mouse genomes, the Rat Genome Sequencing Project Consortium reported that nearly all human genes known to be associated with diseases have counterparts in the rat.
HP and TCAG Collaborate to Advance Medical and Environmental Genomic Discovery in Life Science
A New Spin on Spirochetes
Major Differences Found Between the Genomes of Oral Pathogen Treponema denticola and Related Spiral-Shaped Bacteria that Cause Syphilis and Lyme Disease
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Digging out from the storm
The next day offered more snow and wind: we still needed handheld radios anytime we ventured between the warming hut and any of the vehicles. The wind was so strong that snow began drifting up through the dive hole in the warming hut, and the windows completely glazed over with snow. At one...
Out onto the ice
It took an enormous amount of effort, but on Thursday we ventured out onto the sea ice with our train of sleds and snow machines. The tucker is our strongest (and slowest) vehicle, and it is pulling both our yellow research sled and a pair of snowmobiles. The red Pisten-Bully is pulling a...
Around Mac-town
We are now fully packed and our mobile research sled is ready to go. We are waiting for some final repairs on the Pisten-Bully which will pull our supply sled. The mobile laboratory sled will be pulled by the Sno-Cat Tucker, which also has cab space for six (riding in the mobile lab would...
Ice diatoms!
Today has been a day of preparations, as tomorrow we hope to leave McMurdo Station and head out on the sea ice. Our mobile sled is almost ready for deployment: the carpenters who work for the US Antarctic Program are quite amazing, and our sled has filtration racks for separating different...
Sea-ice class
Today Abigail Noble and I took a Hagglund transporter out onto the Ross Sea to learn the basics of sea ice safety and ice dynamics. The sea ice on McMurdo Sound can be 2 meters thick, but this ice is constantly changing, and when you drive along its surface, you can't assume that it is...
Happy Camp
Our project on the Ross Sea will take us far from heated facilities of McMurdo Station, so all members of our team need to attend "Happy Camp", a two day course on snow camping and basic Antarctic survival. Happy Camp is held out on the McMurdo Ice Shelf, and it is an immersion program in...
McMurdo Station
Entering McMurdo is like entering a modern mining town: lots of exposed rock and unpaved streets, above ground utilities and bare-bones architecture. Utilitarian. From the airport we were taken to a briefing room, introduced to our science coordinators, and given our shcedules. Since I am...
Transport to the ice
Wednesday morning started with a 5AM taxi ride to the US Antarctic Program's processing center at the Christchurch airport, where we had to repack our bags and put on our emergency cold weather gear for the flight. Our plane was the C-17 Globemaster III, a large military transport plane more...
Polynya opens in the Ross Sea
A helicopter pilot recently sent us an image of the area we are planning to sample, and the stable sea ice we intended to use as a platform for drilling and sampling is now a giant stretch of open seawater! A large opening like this is a polynya, a term borrowed from the Russian...
Christchurch, New Zealand
Greetings from Christchurch, New Zealand, the anteroom to Antarctica. My colleagues and I have been here for several days now, running last minute errands, getting equipped with cold weather gear, and waiting for a flight south to McMurdo Station. The flight here was remarkable only in it's...
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Can CRISPR help stop African Swine Fever?
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Getting Under the Skin
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
Planet Microbe
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
The Next Climate Change Calamity?: We’re Ruining the Microbiome, According to Human-Genome-Pioneer Craig Venter
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
Lessons from the Minimal Cell
“Despite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.”
Even Synthetic Life Forms With a Tiny Genome Can Evolve
By watching “minimal” cells regain the fitness they lost, researchers are testing whether a genome can be too simple to evolve.
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
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