Analysis of the Aedes albopictus C6/36 genome provides insight into cell line utility for viral propagation.

Analysis of the Aedes albopictus C6/36 genome provides insight into cell line utility for viral propagation.

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Authors: Miller JR, Koren S, Dilley KA, Puri V, Brown DM, Harkins DM, Thibaud-Nissen F, Rosen B, Chen XG, Tu Z, Sharakhov IV, Sharakhova MV, Sebra R, Stockwell TB, Bergman NH, Sutton GG, Phillippy AM, Piermarini PM, Shabman RS
Title: Analysis of the Aedes albopictus C6/36 genome provides insight into cell line utility for viral propagation.
Citation: GigaScience. 2018-03-01; 7.3: 1-13.
Abstract:
The 50-year-old Aedes albopictus C6/36 cell line is a resource for the detection, amplification, and analysis of mosquito-borne viruses including Zika, dengue, and chikungunya. The cell line is derived from an unknown number of larvae from an unspecified strain of Aedes albopictus mosquitoes. Toward improved utility of the cell line for research in virus transmission, we present an annotated assembly of the C6/36 genome.
PMID: 29329394