Human Health
A healthy, optimal life that enables individuals to achieve their personal potential while staving off disease is the goal for us all. Genetics, combined with different environmental interactions, makes every individual unique and the current one-size-fits-all medical solutions, inadequate. JCVI research is advancing the understanding of human health and disease to enhance lives beyond managing health risks.
Inclusivity, Diversity, Equity, and Access in Genomics
Human Microbiome
Infectious Disease
Synthetic Biology & Health
New LongCOVID research launched by PolyBio’s global consortium of scientists
Funding will deepen research on the persistence of the SARS-CoV-2 virus in LongCOVID patients and launch new clinical trials
Using AI to speed up vaccine development against Disease X
Family resemblance: How T cells could fight many coronaviruses at once
LJI researchers work to head off future pandemics by uncovering key similarities between SARS-CoV-2 and common cold coronaviruses
Privacy concerns sparked by human DNA accidentally collected in studies of other species
Two research teams warn that human genomic “bycatch” can reveal private information
Scientists Unveil a More Diverse Human Genome
The “pangenome,” which collated genetic sequences from 47 people of diverse ethnic backgrounds, could greatly expand the reach of personalized medicine.
First human ‘pangenome’ aims to catalogue genetic diversity
Researchers release draft results from an ongoing effort to capture the entirety of human genetic variation.
JCVI Associate Professor Marcelo Freire elected to the 2022 class of AAAS Fellows
J. Craig Venter Institute Scientists to Investigate Role of Opioid Abuse in HIV and HIV-Associated Neurocognitive Disorders Pathogenesis through $4.7M NIDA Grant
Study aims to identify candidate molecules to regulate HIV infection in the central nervous system in patients abusing opioids
Influenza A Virus Discovered in Heart Muscle Tissue Causing Damage Long After It Has Cleared from the Lungs
Strategies to inhibit necrotic cell death or to prevent mitochondrial damage should be pursued as possible therapies to reduce cardiac damage during influenza infections
Unique Antibody Pattern Discovered in COVID-19 ICU Patients May Be Key to Predicting Severe Outcomes
Synthetic Cell-Powered Lotion to Manage Type 1 Diabetes
Venter Institute Researchers Tackle the Growing Concern of Antibiotic Resistant Bacterial Infections with Genomic, Phage Approaches
J. Craig Venter Institute and UC San Diego Develop Phage Treatment as Potential Cure for Alcoholic Liver Disease
Team targeted specific toxin-producing strains of the bacterium, Enterococcus faecalis, which is shown to be responsible for most liver damage
Combining Antibiotics, Researchers Deliver One-Two Punch against Ubiquitous Bacterium
CWRU/Cleveland VA findings in mouse models could make inroads against superbugs
New Sequencing Technologies Enable Better and Faster Understanding of the Human Microbiome
Zymo Research Recognized by NASA for its Support of Research Aboard the International Space Station
DNA/RNA Shield™ Protects Biological Samples Even in Space
Oral bacteria 'battle royale' helps explain how a pathogen causes hospital infections
When Starved, Dangerous Oral Bacteria Hang On
No More Needles! Using Microbiome and Synthetic Biology Advances to Better Treat Type 1 Diabetes
Fighting Back Against Flu
Rainbow Around The Son Book Chronicles a Mother’s Love and the Mutant p53 Gene
New Bestseller Reveals How One Family Discovered They Carried the Gene with over 90% Chance of Developing Cancer
Every Day is World Food Day at JCVI
Researchers look beyond BMI to predict obesity-related disease risk
Mold Is Everywhere and Impacts You
JCVI Team Awarded Two Grants Under the National Science Foundation’s “Understanding the Rules of Life” Initiative, Building on 20 Years of JCVI Research
Newly Discovered Human Brain Cell: Rosehip Neurons
Scientists identify a new kind of human brain cell
‘Rosehip’ neurons not found in rodents, may be involved in fine-level control between regions of the human brain
S2 Genomics Awarded $280,000 Phase I STTR Grant from the National Institutes of Health
S2 Genomics will develop the Singulator™ system for automated preparation of single cells or nuclei from solid tissue samples
J. Craig Venter Institute Makes Strides in Microbial Analysis of Artwork which May Lead to Better Preservation Techniques
BioVision Alexandria 2018
Variants in non-coding DNA contribute to inherited autism risk
These regulatory elements heighten risk -- and are inherited predominantly from the father
JCVI to Receive Grant from Chan Zuckerberg Initiative to Define the Language of Human Cell Classification
Past encounters with the flu shape vaccine response
Immune history influences vaccine effectiveness, interacting with other potential problems arising from the manufacturing process
Sequencing the Human Genome
The human genome is the complete set of genetic information, stored as DNA within the nucleus of nearly every one of the trillions of cells in the human body. Every person’s genome is different and is a large part of what makes us unique individuals.
Zoo in You Traveling Exhibition
Our bodies are home to trillions of bacteria. This project provides an education resource to middle and high school aged children who are interested in science and medicine.
Western Lowland Gorilla Microbiome
The gastrointestinal microbiota composition and function of free range wild Western Lowland Gorillas mirrors macro-ecological patterns.
TEDDY Infectious Agents
In this study, we propose to investigate the Prokaryotic species associated with the gut microbiome using whole genome shotgun metagenomic sequencing of stool samples via Solexa sequencing technology.
Howler Monkey Microbiome
Gastrointestinal microbial community composition and habitat structure in howler monkeys (Alouatta pigra).
Vaginal Microbiome Project
A metagenomics approach to understanding the relationship between the vaginal microbiome, bacterial vaginosis, vaginal health and preterm birth.
Mouse Microbiome
Enteric dysbiosis associated with a mouse model of alcoholic liver disease. The translocation of bacteria and bacterial products into the circulation contributes to alcoholic liver disease.