James Smith, PhD

Adjunct Faculty

James Smith, DPhil is an adjunct faculty at the J. Craig Venter Institute, and is the Executive Director of the Mirror Biology Dialogues Fund. He works to better understand and address the risks of mirror life, and was part of the group that wrote a 2024 commentary in Science drawing attention to those risks. He has previously held positions at the Center for Long Term Resilience and at RAND Europe focused on biosecurity policy. Prior to this, he was the head of global strategy for Alvea, a vaccine company that completed a phase 1 clinical trial for an omicron targeted pDNA vaccine, where he led regulatory, quality, and aspects of product development.

Dr. Smith holds an undergraduate degree (biological sciences) and UK Medical Research Council funded doctoral degree (medical sciences) from the University of Oxford. He was also a postdoctoral scientist and senior postdoctoral scientist at the University of Oxford, in the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences and the Centre for Statistics in Medicine, a Fellow of Reproducible Research Oxford, and a SENS Research Foundation Scholar at the Harvard Stem Cell Institute.

Publications

Science (New York, N.Y.). 2024-12-20; 386.6728: 1351-1353.
Confronting risks of mirror life
Adamala KP, Agashe D, Belkaid Y, Bittencourt DMC, Cai Y, Chang MW, Chen IA, Church GM, Cooper VS, Davis MM, Devaraj NK, Endy D, Esvelt KM, Glass JI, Hand TW, Inglesby TV, Isaacs FJ, James WG, Jones JDG, Kay MS, Lenski RE, Liu C, Medzhitov R, Nicotra ML, Oehm SB, Pannu J, Relman DA, Schwille P, Smith JA, Suga H, Szostak JW, Talbot NJ, Tiedje JM, Venter JC, Winter G, Zhang W, Zhu X, Zuber MT
PMID: 39666824