Synthetic Biology

The ability to routinely write the software of life has ushered in a new era in science, and with it, new products and applications such as advanced biofuels, clean water technology, and new vaccines and medicines. Synthetic biology is integrated into to most of our other research areas and when combined with JCVI’s genomics expertise, holds great promise for the future. Our team is at the forefront of discoveries and important public dialogue.

Designer Phage

Synthetic Engineering of Bacteriophage for Treatment of Wound Infections

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Developing Genetic Tools to Manipulate African Swine Fever Virus and Generate Attenuated Strains

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No More Needles!

Transforming the Treatment of Type 1 Diabetes

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BREAD: Toward Development of a Vaccine for Contagious Bovine Pleuropneumonia (CBPP)

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Synthetic Genomics to Generate a Stable Epstein-Barr Virus Infectious Clone

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Viral Synthetic Genomics to Engineer Large dsDNA Viruses

Rapid engineering of large dsDNA viruses using synthetic genomics assembly tools.

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Assembly of HSV-1

Use of cutting-edge synthetic genomics technology to revolutionize the study of herpesvirus biology.

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Policy and Regulatory Issues for Gene Drives in Insects

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A Synthetic Human Cytomegalovirus Vaccine Platform

Generation of an HCMV low passage clinical isolate using synthetic genomics.

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First Minimal Synthetic Bacterial Cell

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DNA Synthesis and Biosecurity

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Synthetic Biology and the U.S. Biotechnology Regulatory System: Challenges and Options

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First Self-Replicating Synthetic Bacterial Cell

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Synthetic Genomics: Options for Governance

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22-Dec-2020
Press Release

Hamilton O. Smith, M.D., Synthetic Biology Pioneer and Nobel Laureate, to Step Down from Daily Duties at J. Craig Venter Institute

Dr. Smith will maintain advisory role as professor emeritus

19-Dec-2020
The San Diego Union-Tribune

After saving countless lives, Nobel laureate Hamilton Smith retires as his own health falters

He has been a fixture in San Diego science for decades

21-Sep-2018
Collaborator Release

NSF announces new awards for Understanding the Rules of Life

New projects address genetic, environmental causality in biological systems and processes

24-Jan-2008
Press Release

Venter Institute Scientists Create First Synthetic Bacterial Genome

Publication Represents Largest Chemically Defined Structure Synthesized in the Lab

Team Completes Second Step in Three Step Process to Create Synthetic Organism

28-Jun-2007
Press Release

JCVI Scientists Publish First Bacterial Genome Transplantation Changing One Species to Another

Research is important step in further advancing field of synthetic genomics

13-Nov-2003
Press Release

IBEA Researchers Make Significant Advance in Methodology Toward Goal of a Synthetic Genome

Group Synthesizes Biologically Active Genome of Bacteriophage φX174

IBEA research, funded by Dept. of Energy, is an important advance toward the goal of a completely synthetic genome that could aid in carbon sequestration and energy production

Toward Re-Programming the Gut Microbiome

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