Biochemical and biophysical research communications. 1994-01-14; 198.1: 288-91.

Expressed sequence tags identify a human isolog of the suil translation initiation factor

Fields C, Adams MD

PMID: 7904817


The complete cDNA sequence of a human isolog of the yeast suil translation initiation factor gene was obtained by assembling over 40 expressed sequence tags (ESTs) for this gene obtained from a variety of tissue-specific cDNA libraries. The human suilisol gene product is a 113 amino-acid polypeptide similar to proteins known from yeast, rice, mosquito, and Methanococcus. The identification of suilisol illustrates the utility of assemblies of independent ESTs for deriving full-length cDNA sequences for new human genes.