Publications

Biological psychiatry. 2026-08-24;

Genetic liability to addiction underlies comorbid bipolar and substance use disorders

Ystaas LAR, Parekh P, Parker N, Akkouh I, Birkenæs V, Sønderby IE, Koch E, Hagen E, Frei O, Shadrin A, Andreassen OA, O'Connell KS

PMID: 42636965

Abstract

Bipolar disorder (BIP) frequently co-occurs with heightened substance use (SU) and substance use disorders (SUDs). Although the strong co-occurrence of these heritable traits points to shared genetic susceptibility, the extent to which there are differences in how SU and SUD overlap with BIP genetic architecture remains unclear.

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