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TIGR Leads New Project to Sequence Tetrahymena Genome
April 9, 2003 Two new federal grants will allow scientists to sequence and analyze the genome of the single-celled model organism Tetrahymena thermophila in a collaborative effort that will benefit a wide range of research, from experimental cell and molecular biology to comparative and functional genomics. The Tetrahymena sequencing project is being led by scientists at The Institute for Genomic Research (TIGR), in Rockville, MD, in collaboration with the University of California,...
About Indresh Singh
Indresh K. Singh is director of informatics, leading Informatics Core Services (ICS) at the J. Craig Venter Institute (JCVI). He has been working on development and support of pipelines for processing and analyzing genome sequencing data for thousands of samples on JCVI High-throughput compute facility and AWS cloud.
More than Six Million New Genes, Thousands of New Protein Families, and Incredible Degree of Microbial Diversity Discovered from First Phase of Sorcerer II Global Ocean Sampling Expedition
ROCKVILLE, MD — March 13, 2007 — Researchers from the J. Craig Venter Institute (JCVI) today announced the publication of several studies from the Sorcerer II Global Ocean Sampling Expedition (GOS) in PLoS Biology (www.plosbiology.org) detailing the discovery of millions of new genes, thousands of new protein families and specifically the characterization of thousands of new protein kinases from ocean microbes using whole environment shotgun sequencing and new computational...
Unlocking the Mysteries of the Microbiome
In the early 2000s, JCVI researchers pioneered in the exploration of the human microbiome, the community of microbes that live in and on the human body. Originally while at The Institute for Genomic Research (TIGR, now part of JCVI) Drs. Craig Venter and Hamilton Smith were awarded a grant from DARPA to examine the microbes found in the human gut. This work was carried out by researchers at JCVI and published in 2006 in Science. While this team had previously published 16S surveys of the...
3rd Minimal Cell Workshop
View complete playlist for the workshop on YouTube. Day 1 — September 15, 2023 Time PDT Video Title Presenter Organization PI 5:00 - 5:20 Welcome and introduction John Glass (jglass@jcvi.org) JCVI John Glass 5:20 - 5:35 Building the in silico minimal cell: Achievements and a rallying call for experimental data...
NLM Selects Dr. Richard H. Scheuermann as Scientific Director for the National Library of Medicine
Patricia Flatley Brennan, RN, PhD, Director of the National Library of Medicine (NLM) at the National Institutes of Health (NIH), has named Richard H. Scheuermann, PhD, as NLM’s new Scientific Director following a nationwide search. Dr. Scheuermann is currently the La Jolla campus director at the J. Craig Venter Institute (JCVI). He is expected to begin his role as NLM Scientific Director on September 10, 2023. “NLM is embarking on a bold new direction to optimize NLM’s vibrant...
New wiki on salivary proteins may transform diagnostic testing and personalized medicine
A diagram that shows the interconnectedness of the thousands of salivary proteins originating from blood plasma, parotid glands, and submandibular and sublingual glands. The diagram is one of many tools available to researchers and clinicians through the Human Salivary Proteome Wiki. By Marcene Robinson BUFFALO, N.Y. – To improve the development of new saliva-based diagnostic tests and personalized medicine, the National Institute of Dental and Craniofacial Research...
Scientists Find New Markers For Anthrax Isolates
May 9, 2002 In a pioneering use of genomics as a tool for the forensic analysis of microbes, scientists at The Institute for Genomic Research (TIGR) in Rockville, Md., and at Northern Arizona University in Flagstaff, Az., have found new genetic markers that distinguish the Bacillus anthracis isolate that was used in last fall's bioterror attack in Boca Raton, Florida, from closely related anthrax strains. Their findings, posted on Science Express on May 9 and scheduled for later...
Human Hair Microbiota
Human hair samples are an important trace evidence type for providing leads in forensic investigations. They are used to determine the race, gender, and identity of the individual responsible for a criminal act. Hair also supports its own microbial habitat that is intra- and inter-personal variable, and as such, this little explored substrate has significant potential in forensics microbiome research due to the unique signatures that are available on an individual. We explored...
Surrogate Methods for Profiling Species of the Oral and Gut Microbiome
We engaged in an effort focused on alleviating a substantial barrier facing the human microbiome research community. While powerful, the 16S rDNA gene is insufficiently divergent to allow discrimination of many species and essentially no strains present within communities. The increasing costs of Sanger sequencing has forced most investigators to adopt the use of the Roche, 454 sequencing platform to address the question, “who’s there?” The benefits of the 454 sequence data are...