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Ceres, Inc and TIGR to Collaborate on Analysis of Thousands of Plant Genes
December 19, 2000 Los Angeles, California. Ceres, Inc., a privately held plant genomics company, and The Institute for Genomic Research (TIGR) have announced a collaboration to accurately identify the structure of genes and their encoded proteins in the chromosomes of the plant species Arabidopsis thaliana. Arabidopsis is a model plant species widely used by scientists for genetic studies of agricultural crops and other plants. Since 1996 an international consortium of laboratories,...
CLC bio Signs Strategic Collaborative Agreement with J. Craig Venter Institute
Cambridge, Massachusetts, USA — October 7, 2008 — CLC bio, a world leading full-service bioinformatics solution provider announced today an agreement with the J. Craig Venter Institute, a not-for profit genomic-focused research institute. The accord consists of a multi-year site license for the entire CLC bio bioinformatics suite of products. The goal is to implement CLC bio's enterprise solution as a scientific platform across all JCVI sites. This enterprise solution will...
Global Ocean Sampling Expedition (GOS)
Overview In 2004, after a successful pilot project of shotgun metagenomics sequencing at the Bermuda Atlantic Time Series site, J. Craig Venter, PhD, and a Venter Institute team launched the Sorcerer II Global Ocean Sampling (GOS) Expedition. Inspired by 19th Century sea voyages like Darwin's on the H.M.S. Beagle and Captain George Nares on the H.M.S. Challenger, The Sorcerer II circumnavigated the globe for more than two years, covering a staggering 32,000 nautical miles, visiting 23...
A bioinformatic filter for improved base-call accuracy and polymorphism detection using the Affymetrix GeneChip whole-genome resequencing platform.
DNA resequencing arrays enable rapid acquisition of high-quality sequence data. This technology represents a promising platform for rapid high-resolution genotyping of microorganisms. Traditional array-based resequencing methods have relied on the use of specific PCR-amplified fragments from the query samples as hybridization targets. While this specificity in the target DNA population reduces the potential for artifacts caused by cross-hybridization, the subsampling of the query genome...
Profiling the malaria genome: a gene survey of three species of malaria parasite with comparison to other apicomplexan species.
We have undertaken the first comparative pilot gene discovery analysis of approximately 25,000 random genomic and expressed sequence tags (ESTs) from three species of Plasmodium, the infectious agent that causes malaria. A total of 5482 genome survey sequences (GSSs) and 5582 ESTs were generated from mung bean nuclease (MBN) and cDNA libraries, respectively, of the ANKA line of the rodent malaria parasite Plasmodium berghei, and 10,874 GSSs generated from MBN libraries of the Salvador I and...
mucG, mucH, and mucI Modulate Production of Mutanocyclin and Reutericyclins in Streptococcus mutans B04Sm5.
Streptococcus mutans is considered a primary etiologic agent of dental caries, which is the most common chronic infectious disease worldwide. S. mutans B04Sm5 was recently shown to produce reutericyclins and mutanocyclin through the biosynthetic gene cluster and to utilize reutericyclins to inhibit the growth of neighboring commensal streptococci. In this study, examination of S. mutans and phylogeny suggested evolution of an ancestral S. mutans into three lineages within one S. mutans...
J. Craig Venter, Ph.D. Receives Double Helix Medal from Cold Spring Harbor Laboratory
ROCKVILLE, MD — November 12, 2008 — J. Craig Venter, Ph.D., Founder and President of the J. Craig Venter Institute (JCVI), was awarded the Double Helix Medal from Cold Spring Harbor Laboratory (CSHL) on November 6th at a gala event in New York City. Dr. Venter received the Double Helix Medal along with Dr. James D. Watson for making each of their individual genome sequences available for scientific use on the Internet and for promoting awareness of the public health...
Animal Forensics and Molecular Biology Techniques
A one-day high school workshop for New Hampton School’s Project Week Hosted by the J. Craig Venter Institute, Rockville, Maryland – March 11, 2015 Every March, the New Hampton School, an independent high school in New Hampshire, holds Project Week, an experiential learning program that allows students to choose from a wide array of unique activities, both on and off campus. This year, one project group traveled to Washington D.C. to complete a program on...
Sequence specific detection of DNA using nicking endonuclease signal amplification (NESA).
We have developed a new method for identifying specific single- or double-stranded DNA sequences called nicking endonuclease signal amplification (NESA). A probe and target DNA anneal to create a restriction site that is recognized by a strand-specific endonuclease that cleaves the probe into two pieces leaving the target DNA intact. The target DNA can then act as a template for fresh probe and the process of hybridization, cleavage and dissociation repeats. Laser-induced fluorescence...
Cloning and sequencing of cDNAs for hypothetical genes from chromosome 2 of Arabidopsis.
About 25% of the genes in the fully sequenced and annotated Arabidopsis genome have structures that are predicted solely by computer algorithms with no support from either nucleic acid or protein homologs from other species or expressed sequence matches from Arabidopsis. These are referred to as "hypothetical genes." On chromosome 2, sequenced by The Institute for Genomic Research, there are approximately 800 hypothetical genes among a total of approximately 4,100 genes. To test their...