Search
Key Biological Mechanism is Disrupted by Ocean Acidification
A team led by scientists from Scripps Institution of Oceanography at the University of California San Diego and the J. Craig Venter Institute (JCVI) has demonstrated that the excess carbon dioxide added to the atmosphere through the combustion of fossil fuels interferes with the health of phytoplankton which form the base of marine food webs. Phytoplankton are microscopic plants whose growth in ocean surface waters supports ocean food webs and global marine fisheries. They are also key...
Signature Infiltration and Maintenance on Plasmid Elements creating a Forensic Microbial System (SIMPLE-FMS)
J. Craig Venter Institute (JCVI) is developing a unique microbial barcode (“signature”) that can be easily be deployed in complex environments to create unique microbial signatures for environmental forensics operations. The barcoded signature will be 1) maintained for specific amounts of time in a complex microbial community (microbiome) with minimal disturbance to the native environment; 2) transferable to a diverse array of objects; and 3) contained through control mechanisms...
JCVI Rockville Directions
J. Craig Venter Institute 9605 Medical Center Drive, Suite 150 Rockville, MD 20850 Phone: 301-795-7000 Driving Directions From Baltimore, MD and BWI Airport Take I-95 South to I-495 West (Silver Spring). Follow I-495 West nine miles to I-270 and travel north to Shady Grove Road (Exit 8 West). Continue to the traffic light and turn left onto Shady Grove Road. Make a right at the 4th light onto Key West Ave. (MD 28...
JCVI La Jolla Directions
J. Craig Venter Institute 4120 Capricorn Lane La Jolla, CA 92037 Phone: 858-200-1800 Driving Directions From the South on I-5 (from San Diego Airport) Take the La Jolla Village Drive exitTurn left onto La Jolla Village Drive Stay in left-most non-turn lane Enter left turn lane after Torrey Pines Road intersection Turn left onto Expedition Way Immediate first left is Capricorn Lane Continue to JCVI building From the North on I-5 (from John Wayne...
Past encounters with the flu shape vaccine response
UNIVERSITY OF CHICAGO MEDICAL CENTER New research on why the influenza vaccine was only modestly effective in recent years shows that immune history with the flu influences a person's response to the vaccine. Low effectiveness of the flu vaccine is often blamed on problems with how the vaccine is designed and produced. Sometimes the flu strains chosen for the vaccine are a poor match for those that end up circulating in the public, especially in years when the H3N2 strain predominates....
Social behaviour and gut microbiota in red-bellied lemurs (Eulemur rubriventer): In search of the role of immunity in the evolution of sociality.
Vertebrate gut microbiota form a key component of immunity and a dynamic link between an individual and the ecosystem. Microbiota might play a role in social systems as well, because microbes are transmitted during social contact and can affect host behaviour. Combining methods from behavioural and molecular research, we describe the relationship between social dynamics and gut microbiota of a group-living cooperative species of primate, the red-bellied lemur (Eulemur rubriventer)....
MTGD: The Medicago truncatula genome database.
Medicago truncatula, a close relative of alfalfa (Medicago sativa), is a model legume used for studying symbiotic nitrogen fixation, mycorrhizal interactions and legume genomics. J. Craig Venter Institute (JCVI; formerly TIGR) has been involved in M. truncatula genome sequencing and annotation since 2002 and has maintained a web-based resource providing data to the community for this entire period. The website (http://www.MedicagoGenome.org) has seen major updates in the past year, where it...
VIGOR extended to annotate genomes for additional 12 different viruses.
A gene prediction program, VIGOR (Viral Genome ORF Reader), was developed at J. Craig Venter Institute in 2010 and has been successfully performing gene calling in coronavirus, influenza, rhinovirus and rotavirus for projects at the Genome Sequencing Center for Infectious Diseases. VIGOR uses sequence similarity search against custom protein databases to identify protein coding regions, start and stop codons and other gene features. Ribonucleicacid editing and other features are accurately...
CharProtDB: a database of experimentally characterized protein annotations.
CharProtDB (/charprotdb/) is a curated database of biochemically characterized proteins. It provides a source of direct rather than transitive assignments of function, designed to support automated annotation pipelines. The initial data set in CharProtDB was collected through manual literature curation over the years by analysts at the J. Craig Venter Institute (JCVI) [formerly The Institute of Genomic Research (TIGR)] as part of their prokaryotic genome sequencing projects. The CharProtDB has...
The Protein Naming Utility: a rules database for protein nomenclature.
Generation of syntactically correct and unambiguous names for proteins is a challenging, yet vital task for functional annotation processes. Proteins are often named based on homology to known proteins, many of which have problematic names. To address the need to generate high-quality protein names, and capture our significant experience correcting protein names manually, we have developed the Protein Naming Utility (PNU, /pn-utility). The PNU is a web-based database for storing and applying...