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Towards a comprehensive structural variation map of an individual human genome.
Several genomes have now been sequenced, with millions of genetic variants annotated. While significant progress has been made in mapping single nucleotide polymorphisms (SNPs) and small (
Bacteria on the International Space Station no more dangerous than earthbound strains
Two particularly tenacious species of bacteria have colonized the potable water dispenser aboard the International Space Station (ISS), but a new study suggests that they are no more dangerous than closely related strains on Earth. Aubrie O'Rourke of the J. Craig Venter Institute and colleagues report these findings in a new paper published February 19, 2020 in the open-access journal PLOS ONE. Shortly after the National Aeronautics and Space Administration (NASA) installed...
Signature Infiltration and Maintenance on Plasmid Elements creating a Forensic Microbial System (SIMPLE-FMS)
J. Craig Venter Institute (JCVI) is developing a unique microbial barcode (“signature”) that can be easily be deployed in complex environments to create unique microbial signatures for environmental forensics operations. The barcoded signature will be 1) maintained for specific amounts of time in a complex microbial community (microbiome) with minimal disturbance to the native environment; 2) transferable to a diverse array of objects; and 3) contained through control...
TIGR President Wins ASM's Promega Biotechnology Research Award
June 6, 2005 TIGR President and Director Claire M. Fraser, Ph.D., has been awarded the 2005 Promega Biotechnology Research Award at the annual meeting of the American Society for Microbiology (ASM), the nation's largest life sciences society. The award honors Fraser for her "outstanding contributions to the application of biotechnology through fundamental microbiological research and development." In accepting the award Monday, Fraser delivered a lecture at the ASM's 105th General...
The first genome from the third domain of life.
About Anders M. Dale
Anders Dale, Ph.D., is president, faculty, and board member of the J. Craig Venter Institute (JCVI). Prior to joining JCVI, Dr. Dale was Professor of neurosciences, radiology, and data science at the University of California San Diego. He has also founded and led several AI-focused biotech startups. They include Cortechs.ai, Precision-Health.ai, and Precision-Pro.ai.
Clinical presentation of prostate cancer in black South Africans.
Compared with White Americans, Black American men are at a significant increased risk of presenting with prostate cancer (PCa) and associated mortality, suggesting a link to African-ancestry. However, PCa status within Africa is largely unknown. We address the clinical presentation of PCa within Black South African men.
Complete analysis of the presenilin 1 gene in early onset Alzheimer's disease.
The presenilin 1 gene has recently been identified as the locus on chromosome 14 which is responsible for a large proportion of early onset, autosomal dominantly inherited Alzheimer's disease (AD). We have elucidated the intron/exon structure of the gene and designed intronic primers to enable direct sequencing of the entire coding region (10 exons) of the presenilin gene in a large number of families. This strategy has enabled us to find a further two novel mutations in the gene. We...
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The NIAID Sponsored Pathogen Functional Genomics Resource Center Announces a Call for White Papers in Functional Genomics and Proteomics
The National Institute of Allergy and Infectious Diseases (NIAID)/NIH/DHHS Pathogen Functional Genomics Resource Center (PFGRC) at the J. Craig Venter Institute (JCVI) is announcing a call for White Papers in the areas of Gene Expression studies, Comparative Genomics, Gene Knock Outs, Proteomics and Bioinformatics as well as associated methodologies and technologies. It is our desire to continue to identify the most relevant resources and collaborative opportunities between the scientific...