Comparative genome analysis of 19 Ureaplasma urealyticum and Ureaplasma parvum strains.

Comparative genome analysis of 19 Ureaplasma urealyticum and Ureaplasma parvum strains.

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Authors: Paralanov V, Lu J, Duffy LB, Crabb DM, Shrivastava S, Methé BA, Inman J, Yooseph S, Xiao L, Cassell GH, Waites KB, Glass JI
Title: Comparative genome analysis of 19 Ureaplasma urealyticum and Ureaplasma parvum strains.
Citation: BMC microbiology. 2012-05-30; 12.: 88.
Abstract:
Ureaplasma urealyticum (UUR) and Ureaplasma parvum (UPA) are sexually transmitted bacteria among humans implicated in a variety of disease states including but not limited to: nongonococcal urethritis, infertility, adverse pregnancy outcomes, chorioamnionitis, and bronchopulmonary dysplasia in neonates. There are 10 distinct serotypes of UUR and 4 of UPA. Efforts to determine whether difference in pathogenic potential exists at the ureaplasma serovar level have been hampered by limitations of antibody-based typing methods, multiple cross-reactions and poor discriminating capacity in clinical samples containing two or more serovars.
PMID: 22646228