Publications

01-May-2011

Freire MO, Sedghizadeh PP, Schaudinn C, Gorur A, Downey JS, Choi JH, Chen W, Kook JK, Chen C, Goodman SD, Zadeh HH

Development of an animal model for Aggregatibacter actinomycetemcomitans biofilm-mediated oral osteolytic infection: a preliminary study.

Journal of periodontology. 2011-05-01; 82.5: 778-89.

Biofilm-induced inflammatory osteolytic oral infections, such as periodontitis and peri-implantitis, have complex etiology and pathogenesis. A significant obstacle to research has been the lack of appropriate animal models where the inflammatory response to biofilms can be investigated. The aim of this study is to develop a novel animal model to study the host response to Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans)-biofilm colonizing titanium implants.

PMID: 21222546

This publication is listed for reference purposes only. It may be included to present a more complete view of a JCVI employee's body of work, or as a reference to a JCVI sponsored project.